Hypocalcemia, (Low Blood Calcium) A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
By Kenneth Kee
()
About this ebook
Hypocalcemia is a frequent biochemical disorder that can vary in severity from being asymptomatic in mild cases to presenting as an acute life-threatening crisis.
Hypocalcemia is too low calcium (below 8.4 mg/dL or 2.25 mmol/L) in the blood.
Normal blood Calcium varies from 8.4 to 10.4 mg/dL (2.25-2.6 mmol/L) controlled by 3 main calcium-regulating hormones (parathyroid hormone –PTH, vitamin D, and calcitonin) through their specific effects on the bowel, kidneys, and skeleton.
Calcium and phosphate are interrelated both controlled by the parathyroid hormones and Vitamin D which control the calcium and phosphate exchange between the blood and 3 systems in the body:
1. Skeletal
2. Gastrointestinal
3. Renal
Parathyroid hormones work mainly on the bones and kidney to raise the blood calcium and increase the phosphate excretion.
Vitamin D raises the intestinal absorption of calcium and phosphate.
About 50% of the total serum calcium is attached to protein, and the remaining free ionized calcium is physiologically active.
Serum calcium levels must be corrected for the blood albumin value before confirming the diagnosis of hypercalcemia or hypocalcemia.
Hypocalcemia (corrected serum total calcium level < 2.12 mmol/L) is most often a result of vitamin D inadequacy or hypoparathyroidism, or a resistance to these hormones
Low calcium levels have also been linked with many drugs such as cisplatin, antiepileptics, aminoglycosides, diuretics, bisphosphonates and proton pump inhibitors; there are other causes.
Calcium is a vital mineral, used by the body to build strong bones and teeth.
Calcium is also needed for the heart and other muscles to function properly.
When a person does not get enough calcium, he or she raises the risk of forming disorders like osteoporosis, osteopenia, and calcium deficiency disease (hypocalcemia).
Children who do not get enough calcium may not develop to their full potential adult height.
This low calcium may be due to a variety of factors, such as:
1. Poor calcium intake over a long period of time, especially in childhood
2. Medicines that may decrease calcium absorption
3. Dietary intolerance to foods rich in calcium
4. Hormonal changes, particularly in women
5. Certain genetic factors
Symptoms:
1. Confusion or memory loss
2. Muscle spasms
3. Numbness and tingling in the hands, feet, and face
4. Depression
5. Hallucinations
6. Muscle cramps
7. Weak and brittle nails
8. Easy fracturing of the bones
Signs:
1. Chvostek's sign
2. Trousseau's sign
3. Seizures.
4. Prolonged QT interval
Diagnosis is by:
Blood for the corrected calcium level or ionized calcium level
Treatment:
The patient is treated where symptoms (seizures, tetany) are present or there is a high risk of complications with a serum calcium
Kenneth Kee
Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.Beyond his medical career, Dr. Kee is also an author.He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.Over time, he published various books, many of which provide simple and accessible guides to different health conditions.His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:"A Family Doctor's Tale"This book is a blend of Dr. Kee’s personal experiences and his reflections on being a family doctor in Singapore. It’s a great choice if you're looking for a narrative that combines both medical knowledge and human stories.“Specialized Medical Conditions”Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-depth information about diagnosis, treatment options, and patient management.“Healthcare Management”Some of his works touch on broader aspects of healthcare, discussing patient care, medical ethics, and the role of the family doctor in the healthcare system“Medical Case Studies”“Case Notes from a Family Doctor": This book provides insights into real-life medical cases that Dr. Kee has encountered in his practice, offering readers a behind-the-scenes look at diagnostic processes and patient care.“Health Education”His writings aim to educate the public on maintaining health and preventing diseases, covering topics like healthy living, nutrition, and fitness“Life and death of different Cell”“Life and death of Red Blood Cell” This book describes the beginning of a red blood cell (named Red Bull) from its origin from the bone marrow and its journey around the body before its death in the spleen. Other stories told are Sperm cell, Ovum, Cancer cell etc."Singapore's Medical and Social History"**"My Personal Singapore History":** This book reflects on Singapore's development from a medical perspective, interwoven with personal stories and observations about healthcare in the country.His works are known for simplifying complex medical information, making it accessible to the general public.Dr. Kenneth Kee's books cover a wide range of health and medical topics.He is known for writing in a clear and straightforward manner, making complex medical information accessible to the general public.His works are known for simplifying complex medical information, making it accessible to the general public.If you are looking for a good starting point, "A Family Doctor's Tale" offers a well-rounded introduction to Dr. Kee’s experiences and insights.It is engaging and provides a mix of personal stories and medical knowledge, making it a good entry into his work.One of the best health tips, supported by both medical professionals like Dr. Kenneth Kee and health research, is to focus on preventive care.This means taking steps to maintain your health before problems arise.There are books on Psychological conditions (PTSD) and disorders (Depression, dementia etc) and children books on Time travelMany of his books are available on platforms like Amazon and Smashwords.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"
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Hypocalcemia, (Low Blood Calcium) A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions - Kenneth Kee
Hypocalcemia,
(Low Blood Calcium)
A
Simple
Guide
To
The Condition,
Diagnosis,
Treatment
And
Related Conditions
By
Dr Kenneth Kee
M.B.,B.S. (Singapore)
Ph.D (Healthcare Administration)
Copyright Kenneth Kee 2017 Smashwords Edition
Published by Kenneth Kee at Smashwords.com
Dedication
This book is dedicated
To my wife Dorothy
And my children
Carolyn, Grace
And Kelvin
This book describes Hypocalcemia, Diagnosis and Treatment and Related Diseases which is seen in some of my patients in my Family Clinic.
(What The patient Need to Treat Hypocalcemia)
This eBook is licensed for your personal enjoyment only. This eBook may not be re-sold or given away to other people. If the patient would like to share this book with another person, please purchase an additional copy for each reader.
If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.
Thank the patient for respecting the hard work of this author.
Introduction
I have been writing medical articles for my blog http://kennethkee.blogspot.com (A Simple Guide to Medical Disorder) for the benefit of my patients since 2007.
My purpose in writing these simple guides was for the health education of my patients.
Health Education was also my dissertation for my Ph.D (Healthcare Administration).
I then wrote an autobiolographical account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.com.
This autobiolographical account A Family Doctor’s Tale
was combined with my early A Simple Guide to Medical Disorders
into a new Wordpress Blog A Family Doctor’s Tale
on http://kenkee481.wordpress.com.
From which many free articles from the blog was taken and put together into 800 amazon kindle books and 200 into Smashwords.com eBooks.
Some people have complained that the simple guides are too simple.
For their information they are made simple in order to educate the patients.
The later books go into more details of medical disorders.
The first chapter is always from my earlier blogs which unfortunately tends to have typos and spelling mistakes.
Since 2013, I have tried to improve my spelling and writing.
As I tried to bring the patient the latest information about a disorder or illness by reading the latest journals both online and offline, I find that I am learning more and improving on my own medical knowledge in diagnosis and treatment for my patients.
Just by writing all these simple guides I find that I have learned a lot from your reviews (good or bad), criticism and advice.
I am sorry for the repetitions in these simple guides as the second chapters onwards have new information as compared to my first chapter taken from my blog.
I also find repetition definitely help me and maybe some readers to remember the facts in the books more easily.
I apologize if these repetitions are irritating to some readers.
Chapter 1
Hypocalcemia (Low Blood Calcium)
What is Hypocalcemia?
Hypocalcemia is a frequent biochemical disorder that can vary in severity from being asymptomatic in mild cases to presenting as an acute life-threatening crisis.
Hypocalcemia is too low calcium (below 8.4 mg/dL or 2.25 mmol/L) in the blood.
Normal blood Calcium varies from 8.4 to 10.4 mg/dL (2.25-2.6 mmol/L) controlled by 3 main calcium-regulating hormones (parathyroid hormone –PTH, vitamin D, and calcitonin) through their specific effects on the bowel, kidneys, and skeleton.
Calcium and phosphate are interrelated both controlled by the parathyroid hormones and Vitamin D which control the calcium and phosphate exchange between the blood and 3 systems in the body:
1. Skeletal
2. Gastrointestinal
3. Renal
Parathyroid hormones work mainly on the bones and kidney to raise the blood calcium and increase the phosphate excretion.
Vitamin D raises the intestinal absorption of calcium and phosphate.
About 50% of the total serum calcium is attached to protein, and the remaining free ionized calcium is physiologically active.
Serum calcium levels must be corrected for the blood albumin value before confirming the diagnosis of hypercalcemia or hypocalcemia.
Hypocalcemia (corrected serum total calcium level < 2.12 mmol/L) is most often a result of vitamin D inadequacy or hypoparathyroidism, or a resistance to these hormones
Low calcium levels have also been linked with many drugs such as cisplatin, antiepileptics, aminoglycosides, diuretics, bisphosphonates and proton pump inhibitors; there are other causes.
Calcium is a vital mineral, used by the body to build strong bones and teeth.
Calcium is also needed for the heart and other muscles to function properly.
When a person does not get enough calcium, he or she raises the risk of forming disorders like osteoporosis, osteopenia, and calcium deficiency disease (hypocalcemia).
Children who do not get enough calcium may not develop to their full potential adult height.
A person should consume the advised quantity of calcium per day through the food eaten, supplements or vitamins.
Hypocalcemia ranges from an asymptomatic biochemical abnormality to a life-threatening disorder, depending on the length, severity, and rapidity of development.
What are the causes of Hypocalcemia?
Causes:
Hypocalcemia is caused by loss of calcium from or inadequate entry of calcium into the circulation.
1. Hypoparathyroidism is the most frequent cause of hypocalcemia and often develops because of