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* chore: upgrade gapic-generator-python to 0.43.1

PiperOrigin-RevId: 364411656

Source-Author: Google APIs <[email protected]>
Source-Date: Mon Mar 22 14:40:22 2021 -0700
Source-Repo: googleapis/googleapis
Source-Sha: 149a3a84c29c9b8189576c7442ccb6dcf6a8f95b
Source-Link: googleapis/googleapis@149a3a8

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* changes without context

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* chore(deps): update precommit hook pycqa/flake8 to v3.9.0

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This PR contains the following updates:

| Package | Type | Update | Change |
|---|---|---|---|
| [pycqa/flake8](https://gitlab.com/pycqa/flake8) | repository | minor | `3.8.4` -> `3.9.0` |

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### Release Notes

<details>
<summary>pycqa/flake8</summary>

### [`v3.9.0`](https://gitlab.com/pycqa/flake8/compare/3.8.4...3.9.0)

[Compare Source](https://gitlab.com/pycqa/flake8/compare/3.8.4...3.9.0)

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Source-Author: WhiteSource Renovate <[email protected]>
Source-Date: Tue Mar 23 17:38:03 2021 +0100
Source-Repo: googleapis/synthtool
Source-Sha: f5c5904fb0c6aa3b3730eadf4e5a4485afc65726
Source-Link: googleapis/synthtool@f5c5904

* test(python): use constraints files to check dependency lower bounds

Use a constraints file when installing dependencies for system and unit tests nox sessions.

https://pip.pypa.io/en/stable/user_guide/#constraints-files
> Constraints files are requirements files that **only control which version of a requirement is installed, not whether it is installed or not**. Their syntax and contents is nearly identical to Requirements Files. There is one key difference: Including a package in a constraints file does not trigger installation of the package.

```
testing
├── constraints-3.10.txt
├── constraints-3.11.txt
├── constraints-3.6.txt
├── constraints-3.7.txt
├── constraints-3.8.txt
└── constraints-3.9.txt
```

Going forward, one constraints file (currently 3.6) will be populated with every library requirement and extra listed in the `setup.py`. The constraints file will pin each requirement to the lower bound. This ensures that library maintainers will see test failures if they forget to update a lower bound on a dependency.

See googleapis/python-bigquery#263 for an example

Source-Author: Bu Sun Kim <[email protected]>
Source-Date: Tue Mar 23 10:52:02 2021 -0600
Source-Repo: googleapis/synthtool
Source-Sha: 86ed43d4f56e6404d068e62e497029018879c771
Source-Link: googleapis/synthtool@86ed43d

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