Most starts and finishes in Tirreno-Adriatico
| Pos. | Rider | Starts | Finishes | First | Last |
|---|---|---|---|---|---|
| 1 | Zabel Erik | 16 | 15 | 1993 | 2008 |
| 2 | Pozzato Filippo | 14 | 13 | 2003 | 2018 |
| 3 | Cavendish Mark | 14 | 8 | 2008 | 2024 |
| 4 | Petito Giuseppe | 13 | 13 | 1982 | 1996 |
| 5 | Panizza Wladimiro | 13 | 13 | 1970 | 1983 |
| 6 | Nibali Vincenzo | 13 | 13 | 2007 | 2021 |
| 7 | Moser Francesco | 13 | 13 | 1973 | 1987 |
| 8 | Quinziato Manuel | 13 | 13 | 2003 | 2017 |
| 9 | Sørensen Rolf | 13 | 13 | 1986 | 2001 |
| 10 | Van Avermaet Greg | 13 | 12 | 2009 | 2023 |
| 11 | Bodnar Maciej | 13 | 12 | 2011 | 2023 |
| 12 | Bennati Daniele | 13 | 10 | 2003 | 2018 |
| 13 | Zanini Stefano | 12 | 12 | 1992 | 2006 |
| 14 | Saronni Giuseppe | 12 | 12 | 1977 | 1990 |
| 15 | Klier Andreas | 12 | 11 | 1999 | 2011 |
| 16 | Mazzanti Luca | 12 | 11 | 1998 | 2012 |
| 17 | Caruso Damiano | 12 | 11 | 2011 | 2025 |
| 18 | Spruch Zbigniew | 12 | 11 | 1992 | 2003 |
| 19 | Di Luca Danilo | 12 | 11 | 1999 | 2012 |
| 20 | Bettini Paolo | 12 | 10 | 1997 | 2008 |
| 21 | Tafi Andrea | 12 | 9 | 1990 | 2005 |
| 22 | Visconti Giovanni | 12 | 9 | 2007 | 2022 |
| 23 | Knaven Servais | 11 | 11 | 1998 | 2010 |
| 24 | Vanderaerden Eric | 11 | 11 | 1985 | 1995 |
| 25 | Visentini Roberto | 11 | 11 | 1979 | 1990 |
| 26 | Tosatto Matteo | 11 | 11 | 1999 | 2015 |
| 27 | Pozzovivo Domenico | 11 | 11 | 2010 | 2024 |
| 28 | Scarponi Michele | 11 | 10 | 2005 | 2017 |
| 29 | Petacchi Alessandro | 11 | 10 | 1999 | 2014 |
| 30 | Rebellin Davide | 11 | 10 | 1993 | 2016 |
| 31 | Colombo Gabriele | 11 | 10 | 1995 | 2005 |
| 32 | Boogerd Michael | 11 | 10 | 1995 | 2007 |
| 33 | Petito Roberto | 11 | 10 | 1994 | 2007 |
| 34 | Sagan Peter | 11 | 10 | 2012 | 2023 |
| 35 | Oss Daniel | 11 | 10 | 2010 | 2023 |
| 36 | Freire Óscar | 11 | 10 | 2000 | 2012 |
| 37 | Cancellara Fabian | 11 | 9 | 2006 | 2016 |
| 38 | Svorada Ján | 11 | 9 | 1991 | 2003 |
| 39 | Konyshev Dmitry | 11 | 8 | 1989 | 2002 |
| 40 | Paolini Luca | 11 | 8 | 2002 | 2015 |
| 41 | Bitossi Franco | 10 | 10 | 1966 | 1978 |
| 42 | Clarke Simon | 10 | 10 | 2010 | 2024 |
| 43 | Lelli Massimiliano | 10 | 10 | 1990 | 2004 |
| 44 | Devolder Stijn | 10 | 10 | 2005 | 2016 |
| 45 | De Vlaeminck Roger | 10 | 10 | 1972 | 1984 |
| 46 | Aldag Rolf | 10 | 10 | 1992 | 2005 |
| 47 | Richeze Maximiliano | 10 | 10 | 2006 | 2022 |
| 48 | Hinault Sébastien | 10 | 9 | 1999 | 2012 |
| 49 | Grabsch Bert | 10 | 9 | 2002 | 2012 |
| 50 | Fondriest Maurizio | 10 | 9 | 1988 | 1998 |
| 51 | Gatto Oscar | 10 | 9 | 2008 | 2019 |
| 52 | Van Petegem Peter | 10 | 9 | 1995 | 2007 |
| 53 | Elli Alberto | 10 | 9 | 1987 | 2002 |
| 54 | O'Grady Stuart | 10 | 8 | 2004 | 2013 |
| 55 | Eisel Bernhard | 10 | 8 | 2005 | 2018 |
| 56 | Martens Paul | 10 | 7 | 2008 | 2021 |
| 57 | Michaelsen Lars | 10 | 6 | 1995 | 2007 |
| 58 | Gimondi Felice | 9 | 9 | 1966 | 1977 |
| 59 | Sacchi Fabio | 9 | 9 | 1999 | 2007 |
| 60 | Pellizotti Franco | 9 | 9 | 2001 | 2018 |
| 61 | Schär Michael | 9 | 9 | 2011 | 2023 |
| 62 | Zilioli Italo | 9 | 9 | 1966 | 1975 |
| 63 | Sciandri Maximilian | 9 | 9 | 1991 | 2003 |
| 64 | Formolo Davide | 9 | 9 | 2015 | 2025 |
| 65 | Modolo Sacha | 9 | 9 | 2010 | 2022 |
| 66 | Garzelli Stefano | 9 | 9 | 1999 | 2013 |
| 67 | Hamburger Bo | 9 | 9 | 1993 | 2005 |
| 68 | Argentin Moreno | 9 | 9 | 1981 | 1993 |
| 69 | Majka Rafał | 9 | 9 | 2012 | 2025 |
| 70 | Ganna Filippo | 9 | 9 | 2017 | 2025 |
| 71 | Rooks Steven | 9 | 9 | 1985 | 1994 |
| 72 | Langeveld Sebastian | 9 | 9 | 2008 | 2021 |
| 73 | Wesemann Steffen | 9 | 9 | 1993 | 2006 |
| 74 | Amador Andrey | 9 | 8 | 2011 | 2023 |
| 75 | Poels Wout | 9 | 8 | 2011 | 2025 |
| 76 | Elmiger Martin | 9 | 8 | 2003 | 2014 |
| 77 | Puccio Salvatore | 9 | 8 | 2013 | 2025 |
| 78 | Milesi Marco | 9 | 8 | 1998 | 2006 |
| 79 | Kwiatkowski Michał | 9 | 8 | 2013 | 2025 |
| 80 | Kiryienka Vasil | 9 | 8 | 2007 | 2018 |
| 81 | Vicioso Ángel | 9 | 8 | 2003 | 2017 |
| 82 | Nocentini Rinaldo | 9 | 8 | 2002 | 2015 |
| 83 | Basso Ivan | 9 | 8 | 2001 | 2015 |
| 84 | Arndt Nikias | 9 | 8 | 2014 | 2024 |
| 85 | Pinot Thibaut | 9 | 8 | 2012 | 2023 |
| 86 | Boasson Hagen Edvald | 9 | 7 | 2009 | 2022 |
| 87 | Cimolai Davide | 9 | 7 | 2013 | 2024 |
| 88 | McEwen Robbie | 9 | 7 | 1997 | 2011 |
| 89 | Terpstra Niki | 9 | 7 | 2010 | 2021 |
| 90 | Caruso Giampaolo | 9 | 7 | 2002 | 2015 |
| 91 | Cipollini Mario | 9 | 6 | 1991 | 2005 |
| 92 | Spezialetti Alessandro | 9 | 5 | 1998 | 2012 |
| 93 | Hincapie George | 8 | 8 | 2001 | 2012 |
| 94 | de Jongh Steven | 8 | 8 | 1998 | 2008 |
| 95 | Museeuw Johan | 8 | 8 | 1995 | 2004 |
| 96 | Velo Marco | 8 | 8 | 1997 | 2010 |
| 97 | Høj Frank | 8 | 8 | 2000 | 2010 |
| 98 | Popovych Yaroslav | 8 | 8 | 2003 | 2016 |
| 99 | Zberg Beat | 8 | 8 | 1992 | 2002 |
| 100 | Urán Rigoberto | 8 | 8 | 2010 | 2022 |