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A Facultative Methanotroph For Environmental Remediation Applications A Facultative Methanotroph For Environmental Remediation Applications

This document summarizes a technology for using a specific strain of facultative methanotroph bacteria for environmental remediation applications. The bacteria was isolated from a Michigan bog and can grow on multiple carbon sources as well as degrade chlorinated hydrocarbons and ethenes. It expresses an enzyme that can be used to bind metals for bioremediation of metal-contaminated sites. The technology has potential applications in bioremediating polluted soil and groundwater.

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30 views

A Facultative Methanotroph For Environmental Remediation Applications A Facultative Methanotroph For Environmental Remediation Applications

This document summarizes a technology for using a specific strain of facultative methanotroph bacteria for environmental remediation applications. The bacteria was isolated from a Michigan bog and can grow on multiple carbon sources as well as degrade chlorinated hydrocarbons and ethenes. It expresses an enzyme that can be used to bind metals for bioremediation of metal-contaminated sites. The technology has potential applications in bioremediating polluted soil and groundwater.

Uploaded by

Subs Kats
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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A Facultative Methanotroph for Environmental Remediation Applications

University of Michigan Office of Technology Transfer

Technology #4627

Background
Methanotrophs, organisms that consume methane as their sole source of carbon and energy, are found in a wide variety of environments where methane/ air interfaces develop, including forest and agricultural soils, wetlands, landfills, geothermal areas, among other locations. Most of these bacteria are obligate methanotrophs, i.e. can only grow on C1 substrates, although Methylocella spp. are facultative, and can grow on a variety of organic acids. Experiments and studies with isolated laboratory strains have shown that methanotrophs can degrade a wide range of chlorinated hydrocarbons, particularly chlorinated ethenes, which require remediation processes.
Managed By
Rakhi Juneja Licensing Specialist, Life Sciences, 734-763-3558

Inventors
Jeremy Semrau

Technology
Researchers at the University of Michigan discovered a non-motile strain of facultative Methylocystis isolated from a spring bog in southeast Michigan. This organism is capable of growth on methane, acetate, and ethanol, express a particulate methane monooxygenase (pMMO) in the presence or absence of methane, and can degrade chlorinated ethenes. In particular, the invention provides compounds that bind to a metal atom synthesized by these methanotrophs, which may be used in the bioremediation of metal-contaminated systems.

Patents
US 20120034594

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