Erythropoietin (EPO) is a biologic response modifier that stimulates red blood cell production. It is used to treat anemia secondary to chronic renal failure. Nursing considerations for EPO include monitoring for uncontrolled hypertension, seizures, and hyperkalemia as well as ensuring adequate iron stores and transferrin saturation levels.
Iron is a mineral vital for hemoglobin regeneration and oxygen transport. It is used to prevent and treat iron deficiency anemia. Nursing considerations for iron supplementation include administering it with food to prevent gastrointestinal upset, monitoring for side effects like nausea and constipation, and informing patients about drug and food interactions that can decrease iron absorption. Patients should also be monitored for signs of anemia like pallor
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Drug Study
Erythropoietin (EPO) is a biologic response modifier that stimulates red blood cell production. It is used to treat anemia secondary to chronic renal failure. Nursing considerations for EPO include monitoring for uncontrolled hypertension, seizures, and hyperkalemia as well as ensuring adequate iron stores and transferrin saturation levels.
Iron is a mineral vital for hemoglobin regeneration and oxygen transport. It is used to prevent and treat iron deficiency anemia. Nursing considerations for iron supplementation include administering it with food to prevent gastrointestinal upset, monitoring for side effects like nausea and constipation, and informing patients about drug and food interactions that can decrease iron absorption. Patients should also be monitored for signs of anemia like pallor
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Submitted by: Jillianne M.
Bertiz BSN 4A SCT
Drug Name and Drug Classification Indication Nursing Consideration/s Dosage and Action/s Erythropoietin *Biologic Response modifier *To treat anemia 2o to CRF *EPO is contraindicated in clients (EPO) with: *Stimulates Stimulates the division and >uncontrolled hypertension Brandnames: differentiation of committed >known hypersensitivity to Epogen, Procrit, red blood cell progenitors in mammalian cell-derived Eprex the bone marrow. products >known hypersensitivity to Dosage: *Pregnacy Category: C human albumin A: 50-100U/kg IV/SC *Pharmacokinetics: *Follow the manufacturer’s 3 x wk Absorption: SC,IV Preparation and administration. Distribution: PB:UK Metabolism: t½: 4-13hrs *Evaluation of iron stores should with CRF; occur during the therapy. 20% less w/ N renal function *Tranferrin saturation should be Excretion: In urine at last 100 ng/ml.
*Pharmacodynamics: *Monitor for adverse reactions
IV Onset: 7-10 days like seizures and hyperkalemia. Peak: 2-4 days Duration: UK SC Onset: 7-10 days Peak: 5-42 hrs Duration: UK Submitted by: Jillianne M. Bertiz BSN 4A SCT Drug Name and Drug Classification Indication Nursing Consideration/s Dosage and Action/s Iron *Mineral for antianemia *To prevent and treat iron *Contraindicated in clients with deficiency anemia hemolytic anemia, Peptic ulcer Brandnames: *Vital Vital for hemoglobin and Ulcerative colitis Ferrous sulfate regeneration, specifically it (Feosol, Fer-Iron) enables the RBC *Administer vitamins with food to Ferrous gluconate development and oxygen prevent GI upset. (Fergon, Fertinic) transport via hemoglobin Ferrous fumarate *Caution on intake of chamomile, (Feostat, Fumerin) *Pregnancy Category: A feverfew, peppermint and St. John’s wort for it interfere with the Dosage: *Pharmacokinetics: absorption of iron and other A: 300-325mg qid Absorption:5-30%intestines minerals. ↑ to 650mg PRN/ Distribution: PB:UK as tolerated Metabolism: t½: Uk *Increadead effect of iron with Excretion: Urine, feces, bile viatmin C; decreaded effect of tetracycline, antacids, *Pharmacodynamics: penicillamine PO Onset: 4 days Peak: 7-14 days *Inform clients of side-effects like Duration: 3-4 mos nausea and vomiting, diarrhea, constipation,epigastric pain and refer to the attending nurse upon occurrence for management.