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Copd Patho

This document discusses chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema. Allergens like dust, pollens, and smoke as well as infections from bacteria and viruses can cause inflammation in the lungs. Cigarette smoking is a major risk factor and can lead to a deficiency in alpha-1 antitrypsin which normally protects the lungs. Over time, the inflammation and enzymes breakdown elastic fibers and destroy the walls between air sacs, reducing the ability to exhale air and causing shortness of breath.

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Henry Roque Tagalag
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© Attribution Non-Commercial (BY-NC)
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Download as DOCX, PDF, TXT or read online on Scribd
52 views

Copd Patho

This document discusses chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema. Allergens like dust, pollens, and smoke as well as infections from bacteria and viruses can cause inflammation in the lungs. Cigarette smoking is a major risk factor and can lead to a deficiency in alpha-1 antitrypsin which normally protects the lungs. Over time, the inflammation and enzymes breakdown elastic fibers and destroy the walls between air sacs, reducing the ability to exhale air and causing shortness of breath.

Uploaded by

Henry Roque Tagalag
Copyright
© Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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COPD

ASTHMA

CHRONIC BRONCHITIS

EMPHYSEMA

Allergens (dust, pollens, molds Cigarettes, smoke,etc.)

H. influenza Diplococcus Pneumoniae

Cigarette Smoking

Anti alpha antitrypsin D.

Inflammation of the Bronchi Activates Ige Bradykinin, Histamine, Prostaglandin

Breakdowns of elastin

destruction of alveolar wall septa

Mast cells & Basophils Release Histamine, Leukotrienes, Prostaglandin, Cytokines, Serotonin

Inc. capillary Permeability


Inc. Dead space Dec.pulmonary bed

Fluid/ Cell Exudation Inc. CO2 Edema of mucous membrane Inc.blood flow

Inflammation of bronchial airway Inc. activity of Goblet Cells Vasodilation Hypersecretion of mucous

hypercapnea

Inc. RBC

additional expansion of the thorax

Bronchoconstriction

Plugged airway

pinkish Barrel chest

wheezes

Dec. intrathoracic pressure

Dec. O2 lungs

Persisted Cough

hypoxia

Decreased Oxygen Blood circulation

cyanosis

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