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Ciprobay

Ciprobay is an antibiotic in the quinolone class used to treat various bacterial infections. It works by inhibiting DNA gyrase in bacteria. It comes as tablets from 125-750mg and intravenous infusions from 100-400mg. Common side effects include central nervous system issues, gastrointestinal problems, and tendon damage. It should be used with caution in patients with epilepsy or central nervous system disorders due to risk of seizures.

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2K views

Ciprobay

Ciprobay is an antibiotic in the quinolone class used to treat various bacterial infections. It works by inhibiting DNA gyrase in bacteria. It comes as tablets from 125-750mg and intravenous infusions from 100-400mg. Common side effects include central nervous system issues, gastrointestinal problems, and tendon damage. It should be used with caution in patients with epilepsy or central nervous system disorders due to risk of seizures.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Brand name: Ciprobay

Generic name: Ciprofloxacin


Drug Classification: Antibiotics (Quinolones)
Indications: Infections of the respiratory tract, middle ear, sinuses, eyes, kidneys and urinary tract,
genital organs, abdomen, skin and soft tissues, bones and joints; further, septicemia,
infections in patients with reduced host defense and for selective intestinal
decontamination in immuno suppressed patients.
Mechanism of action: Inhibits DNA-gyrase in susceptible organism; inhibits relaxation of
supercoiled DNA and promotes breakage of double-stranded DNA.
Dose: Tab 125-750 mg orally bid. Respiratory tract infections 500 mg bid. Acute gonorrhea 250
mg orally as single dose. The normal dose must be reduced if creatinine clearance is <
20 ml/min. 500 XR tab acute uncomplicated UTI (acute cystitis) 1 tab/day for 3 days IV
infusion 100-200 mg bid. Resp tract infections 200-400 mg bid. Acute, uncomplicated
UTI and extra genital gonorrhea 100 mg bid. Pre-menopausal cystitis and acute,
uncomplicated gonorrhea single dose 100 mg. Complicated cystitis and diarrhea 200 mg
bid. Severe infections 400 mg tid.
Contraindication: hypersensitivity to ciprofloxacin or other quinolones. Children, adolescents,
pregnancy and lactation.
Special Precautions: Epilepsy, CNS damage. Photosensitivity. May affect ability to drive or
operate machinery.
Adverse Reactions:
CNS: seizures, dizziness, drowsiness, headache, insomnia, acute psychosis, agitation,
confusion, hallucination, increased intracranial pressure, light-headedness, tremors
CV: arrythmias, QT prolongation, vasodilation
GI: hepatotoxicity, pseudomembranous colitis, abdominal pain, diarrhea, nausea, altered
taste. GU: interstitial cystitis, vaginitis. Derm: photosensitivity, phototoxicity
Endo: hyperglycemia, hypoglycemia. Local: phlebitis at IV site
MS: tendonitis, tendon rupture
Misc: hypersensitivity reactions including anaphylaxis, Stevens - Johnson syndrome,
lymphadenopathy.
Form: Tablet (Film- coated) - 250mg, 500mg, 750mg; IV infusion- 100mg/ 50mL,
200mg/ 100mL, 400mg/ 200mL
Pregnancy Risk Category: C
Nursing Responsibilities:
 Assess patient for infection prior to and during therapy.
 Obtain specimens for culture and sensitivity before initiating therapy
 Observe patient for signs and symptoms of anaphylaxis (rash, pruritus, laryngeal
edema, wheezing)
 Monitor prothrombin time closely in patients receiving fluoroquinolones and
warafarin

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