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Wilms Tumor

Wilms' tumor is a type of kidney cancer that typically affects children between ages 3 to 8. It develops from embryonic kidney cells that continue to multiply abnormally. Common signs include abdominal masses, blood in the urine, and reduced appetite. Risk factors include aniridia, hemihypertrophy, undescended testicles, and hypospadias. Staging involves ultrasound, CT scan or MRI. Standard treatment consists of surgery to remove part or all of the affected kidney, along with chemotherapy and sometimes radiation therapy.
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0% found this document useful (0 votes)
148 views

Wilms Tumor

Wilms' tumor is a type of kidney cancer that typically affects children between ages 3 to 8. It develops from embryonic kidney cells that continue to multiply abnormally. Common signs include abdominal masses, blood in the urine, and reduced appetite. Risk factors include aniridia, hemihypertrophy, undescended testicles, and hypospadias. Staging involves ultrasound, CT scan or MRI. Standard treatment consists of surgery to remove part or all of the affected kidney, along with chemotherapy and sometimes radiation therapy.
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WILMS TUMOR Wilms' tumor or nephroblastoma is a tumor of the kidneys that typically occurs in children 3-8 years old.

It was named after Dr. Carl Max Wilhelm Wilms, a German surgeon (18671918) who first described this kind of tumor

SIGNS AND SYMPTOMS: Abdominal mass Fever Blood in the urine Reduced appetite Weight loss High blood pressure In Wilms tumor, cancer cells arise during fetal growth and development. Failure of the kidney cells to develop

Multiplication of kidney cells in their primitive stage

TUMOR

RISK FACTORS: Aniridia failure of the iris to form completely Hemihypertrophy an abnormality wherein one side of the body is noticeably larger than the other side Undescended testicles one or both testicles fail to descend into the scrotum Hypospadias the urethral opening is on the underside instead at the tip of the penis

DIAGNOSTIC TEST ULTRASOUND CT SCAN MRI

STAGES OF WILMS TUMOR Stage I the cancer is found only in the kidneys. Stage II the cancer has spread to the tissues and structures near the kidneys, such as blood vessels. It can be completely removed by surgery. STAGES OF WILMS TUMOR Stage III the cancer spread beyond the kidney area to nearby lymph nodes or other structures within the abdomen. It cant be completely removed by surgery. Stage IV the cancer spreads to distant structures, such as lungs, liver or brain. Stage V cancer cells are in both kidneys

TREATMENT Standard treatment for Wilms tumor are: A. Surgery NEPHRECTOMY the surgical removal of the kidney tissue NEPHRECTOMY Types: Simple nephrectomy surgical removal of the entire kidney Partial nephrectomy removal of the tumor and part of the kidney tissue surrounding it Radical nephrectomy removal of the kidney and surrounding tissues including the lymph nodes B. Chemotherapy Uses medication to kill cancer cells. It maybe given by pill, IV line or an injection C. Radiation therapy Uses x-rays or other sources of high energy rays to kill cancer cells. It usually started within a few days after surgery.

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