Syllabus p2 Sem4
Syllabus p2 Sem4
Elements of immune system-NATURAL & ACQUIRED Immunity. Specific & Non-specific Immune response. CELLS & ORGANS induced in Immune Response. Antigenic Determinants / EPITOPES. Concept of HAPTENS. ADJUANTS TYPES & their APPLICATIONS. IMMUNOGLOBULINS CLASSIFICATION, STRUCTURE & BIOLOGICAL PROPERTIES. ISOTYPE, ALLOTYPE & IDIOTYPIC VARIATIONS. Theories of Antibody Formation. Generation of ANTIBODY DIVERSITY & GENES INVALUED in antibody production.
UNIT III: IMMUNO ANALYTICAL METHODS Production & Immuno Technology & Purification of Polyclonal Abs. Ag-Ab interactions- Gel Diffusion, Immuno Electrophoresis, Immuno Florescence. RIA. ELISA. Western Blotting & FACS techniques. VACCINES- TYPES& APPLICATIONS.(DNA, Recombinant DNA, Peptide& Antiodtypic
Vaccines).
Hybridoma Technology Production of monoclonal Abs & their APPLICATION. UNIT IV: DISORDERS OF IMMUNE RESPONSE HYPERSENSITIVITY- Basic concept types & Mechanism of Activation.
AUTOIMMUNE DISEASES- Classification study of selected autoimmune Diseases.
Immuno Deficiency Disorders-AIDS. Immuno Suppressive Drugs / Agents & their Mechanism of Action.