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Benign Prostatic Hyperplasia - BPH - Pathophysiology - Schematic Diagram

This document summarizes the risk factors, symptoms, diagnosis, and complications of benign prostatic hyperplasia (BPH). It notes that enlarged prostate size can constrict the urethra and bladder outlet, causing incomplete emptying of the bladder and increased urinary pressure. Left untreated, this can lead to further complications like urinary tract infections, damage to the kidneys and bladder, and chronic kidney disease. Laboratory tests are noted throughout as ways to monitor the condition and complications.

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Trixie Arabit
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3K views2 pages

Benign Prostatic Hyperplasia - BPH - Pathophysiology - Schematic Diagram

This document summarizes the risk factors, symptoms, diagnosis, and complications of benign prostatic hyperplasia (BPH). It notes that enlarged prostate size can constrict the urethra and bladder outlet, causing incomplete emptying of the bladder and increased urinary pressure. Left untreated, this can lead to further complications like urinary tract infections, damage to the kidneys and bladder, and chronic kidney disease. Laboratory tests are noted throughout as ways to monitor the condition and complications.

Uploaded by

Trixie Arabit
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Risk Factors: Hx, Age, Diet

Estrogen, Androgen testosterone dihydrostestosterone Cellular proliferation (STROMAL, EPITHELIAL)

Symmetrically enlarged; prostate

PROSTATIC HYPERPLASIA
[static]Prostate encroaching upon prostatic urethra Narrow lumen constricted urethra [dynamic] Additional Tension/pressure of P smooth muscle to bladder neck to bladder neck

Dx of BPH(see NHH); taking Xantral (see drugs)

BLADDER OUTLET OBSTRUCTION


Incomplete emptying the bladder Inc residual urine Rapid filing of urine
pressure inside Urinary bladder contraction to compensate pressure
Frequent urge to urinate [even at night] (See NHH) Chronic condition

to rectum constipation

Dec UO

Injury to tissue/vessel

Bladder wall thickening due to muscle [detrusor] hyperthrophy Weakened bladder contractility [detrusor] (decompensation)

Back up pressure Reflux of urine to ureter (vesico- urethral reflux) Reflux from ureter to KIDNEYS Collecting ducts filled with urine [secondary hydronephrosis] pressure Compression of tissue/ BV Blood flow RAAS activated vasoconstriction
Na & H20 retention

Irritation to the lining inflammation

oxygen supply

Less space

Ischemia
Necrosis/ fibrosis

volume BP

Damaged kidneys (CKD)


Problem in maintaining Ca-PO4 Problem in producing hormone

Problem in excretory functions worsens

GFR
Na K
(See Labs)

Activation Vit D Ca absorption

EPO RBC in circulation

BUN Crea
(See Labs)

(See Labs) Big particles can pass thru filter

PO4

Oxygen
Ca

Pale

weak fatigue nausea dizzy

Pus, RBC, protein leaks Specs of Albumin in urine blood in the (See Labs) urine (See Labs) Pus in the urine (See Labs)

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