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Diagram I Pathogenesis of Insulin Dependent DM (Type 1) : Diagrams

Type 1 diabetes results from an autoimmune destruction of insulin-producing beta cells in the pancreas triggered by genetic and environmental factors such as viral infections. Type 2 diabetes occurs when the body becomes resistant to insulin and the pancreas is unable to produce enough insulin to compensate, due to hereditary factors and obesity which increase insulin demand and eventually cause beta cell exhaustion.

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kristel_nicole18yaho
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226 views

Diagram I Pathogenesis of Insulin Dependent DM (Type 1) : Diagrams

Type 1 diabetes results from an autoimmune destruction of insulin-producing beta cells in the pancreas triggered by genetic and environmental factors such as viral infections. Type 2 diabetes occurs when the body becomes resistant to insulin and the pancreas is unable to produce enough insulin to compensate, due to hereditary factors and obesity which increase insulin demand and eventually cause beta cell exhaustion.

Uploaded by

kristel_nicole18yaho
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Diagrams:

Diagram I
Pathogenesis of Insulin Dependent DM (Type 1)






















Genetic Predisposition (Susceptibility)


Environmental
insult
- Viral infection
- Toxic chemical
agents

Autoimmunity
-Lymphocyte
infiltration
-Insulitis
Immunologic Response
- Islet cell antibodies
- Cell- mediated immunity
cell destruction
Lack of insulin release
Insulin Dependent Diabetes Mellitus (IDDM)





Diagram II
Pathogenesis of Non- Insulin Dependent DM (Type 2)





















Hereditary
Factors
Obesity
Delayed or insufficient insulin
secretion
Insulin resistance (Receptor
defect or other events)
Increased insulin demand
cell exhaustion and dysfunction
Impaired secretion
of insulin
Hyperglycemia
Non- Insulin Dependent DM (NIDDM)

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