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Exercise No 6 - On of Vitamin B Complex Skin Testing

Skin testing is done before admixtures in order to detect if the patient has an underlying allergy to a certain drug or admixture of drugs. Some of the manifestations of skin allergy to Vitamin B complex are hives, eczema, psoriasis, rhinitis, etc.

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2K views

Exercise No 6 - On of Vitamin B Complex Skin Testing

Skin testing is done before admixtures in order to detect if the patient has an underlying allergy to a certain drug or admixture of drugs. Some of the manifestations of skin allergy to Vitamin B complex are hives, eczema, psoriasis, rhinitis, etc.

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pharmaebooks
Copyright
© Attribution Non-Commercial (BY-NC)
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Name: RAFAEL, DUNE VIENIS KAREN N.

Year & Section: BS-


Pharmacy 4A
Group No.: _____________________ Date Started: November 27,
2009
Date Submitted: December 07,
2009

Exercise No. 6
PREPARATION OF VITAMIN B COMPLEX SKIN TESTING

I. Objectives:
i. To prepare Vitamin B Complex testing solution for skin testing,
ii. To acquire skills in proper method of mixing Vitamin B complex with
Vitamin C, and
iii. Identify the manifestations of skin allergy to vitamin B complex

I. Data Output:

1. Get 0.1 ml of the preparation.


5 mg 1.7 mg =
3 ml 0.1 ml
2. Dissolve solution #1 with 1.0 ml of distilled water.
1.7 mg 1.7 mg =
0.1 ml + 1.0 ml 1.1 ml
3. Get 0.1 ml from solution #1 and add 0.9 ml of sterile normal saline
solution.
1.7 mg 0.1545 mg = 0.1545 =
mg
1.1 ml 0.1 ml + 0.9 ml 1 ml
4. Discard 0.9 ml and give only 0.1 ml for skin testing.
0.1545 mg 0.01545 mg 15.45 mcg
= =
1 ml 0.1 ml 0.1 ml
Labelling:

Saint Luke’s Hospital


Father Selga Street, Davao City
Patient’s Name: Robert John R. Rafael Age: 23 Sex: Male
Attending Physician: J. Noveno, MD. Room No.: 47

Vitamin B Complex (Neurobion®)


15.45 mcg/ 0.1 ml solution for Skin Testing

Prepared by: Dune Rafael, RPh


Pharmacist

I. Answers to Questions:
1. What are some of the Vitamin B complex available in the market
today?
Some of the Vitamin B complex available in the market today
are Benutrex®, Capsugen®, Hybutin®, Meganerv®, Neurobion®,
Polynerv®, Vitagen®, Supraneuron®, etc.
2. Why do you think skin testing is done before admixtures?
I think skin testing is done before admixtures in order to detect
if the patient has an underlying allergy to a certain drug or admixture
of drugs.

3. What are some of the manifestations of skin allergy to vitamin B


complex?
Some of the manifestations of skin allergy to vitamin B complex
are skin rash, hives, or itchy or swollen skin.

I. Conclusion:
The B vitamins are eight water-soluble vitamins that play important
roles in cell metabolism. B vitamins are necessary in order to support and
increase the rate of metabolism, maintain healthy skin and muscle tone,
enhance immune and nervous system function, promote cell growth and
division and reduces the risk of pancreatic cancer. B-vitamins are needed
in order to treat various b-vitamin deficiencies like beriberi,
ariboflavinosis, pellagra, macrocytic anemia and peripheral neuropathy.
Before the administration of vitamin B complex intravenously, a
skin test must be conduction. The appearance of skin rashes, redness and
swelling of the skin indicates that the patient is allergic to vitamin B-
complex.

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