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A 1000-liter continuous stirred tank reactor (CSTR) uses glucose as a substrate to produce biomass. The microbes follow Monod kinetics with a maximum growth rate of 0.4 h-1, a high substrate half-saturation constant of 1.5 g/l, and a yield of 0.5 g biomass per g substrate consumed. The CSTR normally operates with a sterile feed of 10 g/l glucose at 100 liters per hour. With the addition of a 10 liter per hour recycle stream containing biomass five times the reactor exit concentration, a schematic diagram of the new system is required.

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502 views

Quiz 1 Answers

A 1000-liter continuous stirred tank reactor (CSTR) uses glucose as a substrate to produce biomass. The microbes follow Monod kinetics with a maximum growth rate of 0.4 h-1, a high substrate half-saturation constant of 1.5 g/l, and a yield of 0.5 g biomass per g substrate consumed. The CSTR normally operates with a sterile feed of 10 g/l glucose at 100 liters per hour. With the addition of a 10 liter per hour recycle stream containing biomass five times the reactor exit concentration, a schematic diagram of the new system is required.

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QUIZ 1 (ANSWERS SCHEME)

BIOREACTOR SYSTEM

Consider a 1000-l CSTR in which biomass is being produced with glucose as the substrate.
The microbial system follows a Monod relationship with m = 0.4 h-1, Ks= 1.5g/l (an
unusually high value), and the yield factor Y X/S = 0.5 g biomass / g substrate consumed. If
normal operation is with a sterile feed containing 10 g/l glucose at a rate of 100 l/h:

(i)

Sketch the operational of 1000-l CSTR according to the above statement with
symbols.

Consider above question, if recycle is used with a recycle stream of 10 l/h and a recycle
biomass concentration five times as large as that in the reactor exit,

(ii)

Sketch an appropriate schematic diagram for the reactor system from the given
condition with symbols.

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