Scribd
Upload
79 views

Transcription Factors: A2 Biology Topic 7

Transcription factors are proteins that bind to DNA at promoter regions and regulate the initiation of transcription. They work by either activating or repressing gene expression. Transcription factors form transcription initiation complexes that recruit RNA polymerase to start transcription. Some factors are present constitutively in cells while others are activated at specific developmental stages or in response to hormones and growth factors.

Uploaded by

burhan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
79 views

Transcription Factors: A2 Biology Topic 7

Transcription factors are proteins that bind to DNA at promoter regions and regulate the initiation of transcription. They work by either activating or repressing gene expression. Transcription factors form transcription initiation complexes that recruit RNA polymerase to start transcription. Some factors are present constitutively in cells while others are activated at specific developmental stages or in response to hormones and growth factors.

Uploaded by

burhan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
You are on page 1/ 6

Transcription Factors

A2 Biology Topic 7

Transcription is initiated by RNA polymerase and


protein transcription factors binding to DNA
RNA polymerase

Promotor region
DNA

Gene

Transcription factors

Gene is switched on by formation of the transcription


initiation complex binding to the promotor region

RNA synthesis

DNA

Transcription initiation complex

Gene

Transcription factors

Some are present in all cells


Some are present in particular cells

Most created in an inactive


form and activated by
hormones or growth factors

Some are present at a particular


stage of development

Activator molecules stimulate


the binding of the transcription
initiation complex

Genes are switched off by repressor molecules


Repressor molecule binds
to promotor region

Repressor molecule

promotor

gene

Repressor molecule binds


to transcription factors

Repressor molecule
(Inactive transcription
factor)
promotor

gene

Repressor molecule

Repressor molecules prevent the formation of the


transcription initiation complex

Activity 7.21

You might also like