MRI Principles (Advanced)
MRI Principles (Advanced)
Wen-Yang Chiang
Oct 13, 2007
Diffusion
Tractography
MRS
http://www.med.umich.edu/opm/newspage/2004/b
raintumor.htm
HIFU
http://www.mrisprostatecancercenter.com/
dr-wheeler_the_prostate_center_hifu.html
Functional
MRI
B0
Provide spatial
information
MRI
Magnetic Resonance Imaging
The alignment of nuclear
Transform the received
spin using external
signal to image
magnetic field
Apply RF pulse which is
close to Larmor frequency
Resonance
Basic Physics
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Basic Physics
Nuclear Spin
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Basic Physics
0 B0
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Basic Physics
Net Magnetization
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Signal
Formation
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Signal
Formation
90 Pulse
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Signal
Formation
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Signal
Formation
180 Pulse
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Signal
Formation
Relaxation
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Signal
Formation
Slice Selection
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Signal
Formation
Slice Selection
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Signal
Formation
Frequency Encoding
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Signal
Formation
Frequency Encoding
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Signal
Formation
Phase Encoding
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Signal
Formation
Phase Encoding
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Signal Interpretation
Spatial Encoding
B
dB
g
dx
S ( g , t ) ( x )e jgxt dx
Different g or t
Signal Interpretation
Sinusoidal Encoding
Signal Interpretation
B(x) = gx x
Spatial Encoding
B
C
x
C
Signal Interpretation
Sinusoidal Modulation
2D sinusoidal wave function
y
x
y-dir gradient
x-dir gradient
jgvt
S ( g , t ) (v )e
dv ,
v ( x, y )
Image Formation
MRI Reconstruction
jkv
1
(v )
S ( k )e
dk ,
v ( x, y )
k gt
Image Formation
Contrast
Image Formation
Contrast
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TR
90
180
echo
90
TE/2
RF
FID
Spin Echo
gz
kx
gy
gx
ky
Kmax
kx
Kmax = Kmax/2
Blurring
ky
Kmax
kx
k = 2 k
Aliasing