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Drug Study

Oxytocin is used to induce labor, control postpartum bleeding, and assist in abortion. It works by stimulating uterine and mammary gland smooth muscles. Common side effects include increased heart rate and blood pressure. It is contraindicated in cases of cephalopelvic disproportion, fetal distress without imminent delivery, prematurity, and severe preeclampsia. Nurses must monitor for side effects like fluid overload and seizures, never administer oxytocin by multiple routes simultaneously, and notify the physician if contractions are too frequent, strong, or long.
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100% found this document useful (1 vote)
41 views

Drug Study

Oxytocin is used to induce labor, control postpartum bleeding, and assist in abortion. It works by stimulating uterine and mammary gland smooth muscles. Common side effects include increased heart rate and blood pressure. It is contraindicated in cases of cephalopelvic disproportion, fetal distress without imminent delivery, prematurity, and severe preeclampsia. Nurses must monitor for side effects like fluid overload and seizures, never administer oxytocin by multiple routes simultaneously, and notify the physician if contractions are too frequent, strong, or long.
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DRUG STUDY

Name
(Brand
Name)
Oxytocin
(Pictopin,
Syntocinon)

Indication

Dosage, Route,
Frequency

For stimulation of
Indication:
labor:
10 units (1ml)
Induction of
of drug infused in 1L
labor at
D5LRS before deliver
term;
control of
For Reduction of
Postpartum
postpartum
bleeding:
1 amp after
bleeding;
delivery of placenta
adjunctive
therapy in
management
of abortion

Mechanism
of Action

Adverse Reaction

Contraindication

Nursing Responsibility

Oxytocin

Causes
potent and
selective
stimulation
of uterine
and
mammary
gland
smooth
muscles

producing
sustained
contractions

Induces
labor and
milk
ejection and
reduces post
partum
bleeding

Cardiovascular:
hypertension;
increased heart rate,
systemic venous
return, and cardiac
output, and
arrhytmias

>Contraindicated in patients
hypersensitive to the drug or
any of its component.

> Monitor and record uterine


contractions, heart rate, BP,
intrauterine pressure, fetal
heart rate, and blood loss q15.

CNS: seizures,
coma from water
intoxication
Gastrointestinal:
Nausea, vomiting,
GU: titanic uterine
contractions,
abruption
placentae, impaired
uterine blood flow
Hematologic:
afibrinogenemia
Respiratory:
anoxia, asphyxia

> Also contraindicated in


cephalopelvic disproportion
or delivery that requires
conversion, as in tranverse
lie; in fetal distress when
delivery isnt imminent; in
prematurity and in severe
toxemia, hypertonic uterine
patterns, total placenta previa
or vasa previa.
> Also contraindicated in
fetal distress.

>Be alert for adverse reaction


>Monitor I/O. Antidiuretic
effect may lead to fluid
overload, seizures, and coma
>never give oxytocin
simultaneously by more than
one route.
>have 20% solution
magnesium sulfate available
for relaxation of the
myometrium.
>If contractions are less than
2 minutes apart, if theyre
above 50mm Hg ,or if they
last 90seconds or longer, stop
infusion, and turn patient on
her side, and notify physician

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