The HGP
The HGP
Background: The Human Genome Project (HGP) was an international research effort to determine the
sequence of the human genome and identify the particular traits each gene represents. The work of the HGP
allowed researchers to begin understanding the blueprint for building a person. As researchers learn more
about the functions of genes and proteins, this knowledge will have a major impact in the fields of medicine,
biotechnology, and the life sciences. We now have identified just over 20,000 human genes, including several
disease-causing genes, and we now have the ability to use DNA like a medicine to treat these diseases. Other
possibilities include the creation of new humans with specifically sorted DNA allowing them to have designed
physical traits, such as for beauty, health, and strength. The technology is ready, but the question remains:
should we alter a persons genes?
How do DNA, RNA, single nucleotide polymorphism, and gene insertion work?
What is the relationship between DNA, proteins, and disease?
Approximately what percentage of a persons DNA is different from any other human?
What are the arguments for and the arguments against altering a persons genes?
2. Tri-fold Board (required information listed; feel free to include additional information):
Include the function, structure, purpose, and nitrogen bases of DNA, including the production
of proteins from DNA and a diagram of how genes are spliced
Include information about diseases related to DNA and genes, and how these diseases can be
treated through human genetic technology
Include the arguments for and the arguments against altering a persons genes for medical and
designer purposes