Book Reviews: Chemistry Pharmacology Natural Products: Saponins. K
Book Reviews: Chemistry Pharmacology Natural Products: Saponins. K
Book Reviews
Chemistry & Pharmacology of Natural Products:
Saponins. K. Hostettmann and A. Marston. Cambridge University Press, New York, NY. 1995. xii +
548 pp. 15 x 22.5 cm. ISBN 0-521-32970-1. $120.00.
This monograph provides a comprehensive, up-todate, and timely review of saponins. These glycosides
of triterpenes, steroids, or steroid alkaloids are commonly found in higher plants and in the marine phylum
Echinodermata. The seven chapters of this volume are
preceded by a helpful glossary to guide the reader
through the abbreviations employed (primarily in the
description of oligosaccharides) and acronyms used to
denote various two-dimensional nuclear magnetic resonance experiments and mass spectrometric techniques.
Following an introductory Chapter 1which contains
brief sections devoted t o definitions, biosynthesis, aglycone classes, nomenclature, and stereochemistry, is
an extensive Chapter 2 reviewing the occurrence and
distribution of the three main classes of saponins.
Isolation and analysis is the subject of the third chapter,
and Chapter 4, devoted to structure determination,
explores traditional cleavage reactions prior to an
extensive and well-illustrated account of nuclear magnetic resonance, mass spectrometric, and other methods.
The discussion covers applications of some seven different mass spectrometric techniques and over a dozen
high-field two-dimensional nuclear magnetic resonance
experiments.
Two chapters are devoted to pharmacological and