Scribd
Upload
2K views13 pages

Animal Biotech

Animal cell culture techniques are used in cell and molecular biology research. Cell cultures can serve as model systems to study basic cell biology, the interaction between cells and disease-causing agents, and the effects of drugs. Specifically, cell cultures are used for cancer research, virology, toxicity testing, vaccine production, and genetically engineering proteins. Cell cultures also allow for genetic counseling by examining chromosomes and detecting fetal disorders.

Uploaded by

Ajay Pratap Singh Chauhan
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
2K views13 pages

Animal Biotech

Animal cell culture techniques are used in cell and molecular biology research. Cell cultures can serve as model systems to study basic cell biology, the interaction between cells and disease-causing agents, and the effects of drugs. Specifically, cell cultures are used for cancer research, virology, toxicity testing, vaccine production, and genetically engineering proteins. Cell cultures also allow for genetic counseling by examining chromosomes and detecting fetal disorders.

Uploaded by

Ajay Pratap Singh Chauhan
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
You are on page 1/ 13

Applications of Animal Cell

Culture Technique
Introduction: 

Animal cells extracted from their tissue or organs


are cultured in aseptic laboratory with
environmental conditions same as in vivo and this
technique is called as animal cell culture. Animal
cells can grow as anchorage dependant or
suspension culture. Cell culture techniques are used
in cell and molecular biology research and studies.
Some of the important areas where cell culture
plays an important role are toxicity testing, cancer
research, virology, gene therapy, drug discovery and
many more. 
Animal Cell Culture Applications: 
Model System: 

Cell culture are used as model system to study basic


cell biology and biochemistry, to study the
interaction between cell and disease causing agents
like bacteria, virus, to study the effect of drugs, to
study the process of aging and also it is used to
study triggers for ageing. 
Cancer Research: 
The basic difference between normal cell and
cancer cell can be studied using animal cell culture
technique, as both cells can be cultured in
laboratory. Normal cells can be converted into
cancer cells by using radiation, chemicals and
viruses. Thus, the mechanism and cause
of cancer can be studied. Cell culture can be used to
determine the effective drugs for selectively destroy
only cancer cells. 
Virology: 
Animal cell cultures are used
to replicate the viruses
instead of animals for the
production of vaccine. Cell
culture can also be used to
detect and isolate viruses,
and also to study growth and
development cycle of viruses.
It is also used to study the
mode of infection. 
Toxicity Testing: 

Animal cell culture is used to


study the effects of new drugs,
cosmetics and chemicals on
survival and growth of a
number of types of
cells.Especially liver and kidney
cells. Cultured animal cells are
also used to determine the
maximum permissible dosage
of new drugs. 
Vaccine Production: 

Cultured animal cells are used in the production of


viruses and these viruses are used to produce
vaccines. For example vaccines for deadly diseases
like polio, rabies, chicken pox, measles and
hepatitis B are produced using animal cell culture. 
Genetically Engineered Protein: 

Animal cell cultures are used


to produce commercially
important genetically
engineered proteins such as
monoclonal antibodies,
insulin, hormones, and much
more. 
Genetic Counselling: 

Fetal cell culture extracted from pregnant women


can be used to study or examine the abnormalities
of chromosomes, genes using karyotyping, and
these findings can be used in early detection of
fetal disorders. 
Genetic Engineering: 
Cultured animal cells can be used
to introduce new genetic material
like DNA or RNA into the cell.
These can be used to study the
expression of new genes and its
effect on the health of the cell.
Insect cells are used to produce
commercially important proteins
by infecting them with genetically
altered baculoviruses
Drug Screening and Development: 

Animal cell cultures are used to study the


cytotoxicity of new drug. This is also used to find
out the effective and safe dosage of new drugs.
Now these tests are being conducted in 384 and
1536 well plates. Cell-based assay plays an
important role in pharmaceutical industry. 
Conclusion: 

Animal cell culture technique plays an important


role in research and development of drug
discovery and also helps in improving the health
and quality of life of patients suffering from
dangerous diseases like cancer, genetic disorders. 

You might also like