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Human CD Chart

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0% found this document useful (0 votes)
313 views

Human CD Chart

Uploaded by

coffeeaddicted
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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BD Biosciences

Official Poster of the 8th International Workshop


on Human Leukocyte Differentiation Antigens
05-810095-3A

Available at BD

Available at BD

Available at BD

Available at BD
Endothelial Cell

Endothelial Cell

Endothelial Cell

Endothelial Cell
Dendritic Cell

Dendritic Cell

Dendritic Cell

Dendritic Cell
Macrophage/

Macrophage/

Macrophage/

Macrophage/
Granulocyte

Granulocyte

Granulocyte

Granulocyte
Epithelial Cell

Epithelial Cell

Epithelial Cell

Epithelial Cell
Erythrocyte

Erythrocyte

Erythrocyte

Erythrocyte
Stem Cell/

Stem Cell/

Stem Cell/

Stem Cell/
Monocyte

Monocyte

Monocyte

Monocyte
Precursor

Precursor

Precursor

Precursor
Platelet

Platelet

Platelet

Platelet
NK Cell

NK Cell

NK Cell

NK Cell
MW (kDa) MW (kDa) MW (kDa) MW (kDa)
B Cell

B Cell

B Cell

B Cell
T Cell

T Cell

T Cell

T Cell
Alternative Ligands and Gene Alternative Ligands and Gene Alternative Ligands and Gene Alternative Ligands and Gene
CD Name associated molecules
Unreduced/
Reduced
Locus CD Name associated molecules
Unreduced/
Reduced
Locus CD Name associated molecules
Unreduced/
Reduced
Locus CD Name associated molecules
Unreduced/
Reduced
Locus

CD1a R4 ,T6, HTA-1 49/- 1q22-q23 CD66b CD67, CGM6, NCA-95 CD66c,e, Src kinases 95-100 19q13.2 CD151 PETA-3, SFA-1 α3, α6-integrins 32/- 11p15.5 CD235a Glycophorin A 4q28-q31
CD62E, Galectins, CD66a,b,c,e,
CD1b R1 45/ 1q22-q23 CD66c NCA, NCA-50/90 Src kinases 90 19q13.2 CD152 CTLA-4 CD80, CD86, PI3-kinase, PTP1D 50/33 2q33 CD235ab Glycophorin A & B 4q28-q31

CD1c M241, R7 43/- 1q22-q23 CD66d CGM1 35 19q13.2 CD153 CD30L, TNSF8 CD30 40 9q33 CD236 Glycophorin C & D 30-40 2q14-q21

19q13.2- CD40L, gp39, TRAP-1,


CD1d R3 49 1q22-q23 CD66e CEA CD66a,c,e 180-200
q13.2
CD154 T-BAM CD40 33 Xq26 CD236R Glycophorin C, GYPC 40 2q14-q21

CD1e R2 28 1q22-q23 CD66f SP-1, PSG 54-72 19q13.2 CD155 PVR 60-90 19q13.2 CD238 Kell Endothelin-3 93 7q33

CD2 E-rosette R, T11, LFA-2 CD58, CD48, CD59, CD15 50/- 1p13 CD68 gp110, Macrosialin LDL 110 17p13 CD156a CD156, ADAM8, MS2 Myeloid -/69 10q26.3 CD239 Lu/B-CAM Laminin 78-85 19q13.2
AIM, EA 1, MLR3, 12p13- 1p34.3-
CD3 T3 20-26 11q23 CD69 gp34/28, VEA 60
p12 CD156b TACE, ADAM17, cSVP pro-TNF, pro-TGF, MAD2 100-120/ 2p25 CD240 30 p36.1
12pter- 15q2; 6p11-
CD4 L3T4, W3/25, T4 MHC Class II, gp120, IL-16 55
p12 CD70 Ki-24, CD27 ligand CD27 55-170 19p13 CDw156C ADAM10 98
15q22
CD241 RhAG/Rh50 50 p21.1
CD72, BCR, gp35-37, 3q26.2-
CD5 T1, Tp67, Leu-1, Ly-1 ZAP-70, TCR, CD21 58/67 11q13 CD71 T9, Transferrin receptor Transferrin 190/95
qter CD157 Mo5, BST-1 NAD, Cyclic ADP-ribose 42-45/42-45 4p15 CD242 ICAM-4/LW LFA-1, Mac-1, VLA-4 37-43 19p13.3

CD6 T12 gp40, gp90, CD166 (ALCAM) -/105-130 11q13 CD72 Ly-19.2, Ly-32.2, Lyb-2 CD5 43/39 9p13.3 CD158a† KIR2DL1, p58.1 HLA-Cw4,2,5,6 58/58 19q13.4 CD243 MDR-1 180 7q21.1

17q25.2-
CD7 gp40, Leu 9 PI3-Kinase 38/40
q25.3 CD73 Ecto-5'-nuclotidase AMP 69-72 6q14-q21 CD158b1† KIR2DL2, p58.2 HLA-Cw3,1,7,8 58/58 19q13.4 CD244 2B4, P38, NAIL CD48 70/70 1q23.3

CD8a Leu2, T8, Lyt2,3 MHC I, Lck 68/30-34 2p12 CD74 li, invariant chain HLA-DR, CD44 41 5q32 CD158b2† KIR2DL3, p58.3 HLA-Cw3,1,7,8 58/58 19q13.4 CD245 p220/240 Lymphocyte receptor 220-250

CD8b CD8, Leu2, Lyt3 MHCI, Lck 32-34 2p12 CD75 sialo-masked Lactosamine CD22 CD158c† KIR2DS6, KIRX 19q13.4 CD246 ALK, p80, Ki-1 Pleiotrophin 200 2p23

CD63, CD81,CD82, CD41/CD61, α2,6 sialylated


CD9 p24, DRAP-1, MRP-1
HLA-DR, β1 Integrins, PI4-Kinase
-/24,26 2p13 CD75S Lactosamine CD22 (proposed) CD158d† KIR2DL4 HLA-Bw4 19q13.4 CD247 CD3 Zeta Chain 2p23

CALLA, NEP, gp100, 3q25.1-


CD10 EC 3.4.24.11 100/-
q25.2
CD77 Pk antigen, BLA, CTH/Gb3 Shiga toxin, Verotoxin 1, CD19 1 CD158e1/e2† KIR3DLI/S1, p70 HLA-Bw4 70/70 19q13.4 CD248 TEM1, Endosialin CD164 sialomucin-like 1 175 11q13

CD11a LFA-1α, α L Integrin chain ICAM-1, 2, 3, 4 170/180 16p11.2 CD79a Igα, MB1 Ig, CD5, CD19, CD22, CD79b -/40-45 19q13.2 CD158f† KIR2DL5 19q13.4 CD249 Aminopeptidase A BP-1, gp160 160 4q25
αM Integrin chain, CR3, iC3b, Fibrinogen, ICAM-1,2, OX40L, TNF(ligand)
CD11b Mo1, C3niR, Mac-1 Factor X 165/170 16p11.2 CD79b Igβ, B29 Ig, CD5, CD19, CD22, CD79a -/37 17q23 CD158g† KIR2DS5 19q13.4 CD252 superfamily, member 4 CD134 (OX40) 34 1q25

αX Integrin, 3q13.3- TRAIL, TNF (ligand)


CD11c p150,95, AXb2
iC3b, Fibrinogen, ICAM-1 145/150 16p11.2 CD80 B7, B7-1, BB1 CD28, CD152 (CTLA-4) 60/-
q21
CD158h† KIR2DS1, p50.1 HLA-C 19q13.4 CD253 superfamily, member 10 Apo2 33 - 34 3q26

TRANCE, RANKL, TNF (ligand)


CDw12 p90-120 150-160/120 CD81 TAPA-1 Leu-13, CD19, CD21 26/- 11p15 CD158i† KIR2DS4, p50.3 HLA-C 50/50 19q13.4 CD254 superfamily, member 11
RANK 35 13q14

15q25- MHC-I, MHC-II, CD4, APRIL, TALL2, TNF (ligand)


CD13 APN, gp150, EC 3.4.11.2 NGR 150/-
q26
CD82 4F9, C33, IA4, KAI1, R2
CD8, β1 Integrins 45-90/- 11p11.2 CD158j† KIR2DS2, p50.2 HLA-C 19q13.4 CD256 superfamily, member 13 BCMA, TACI 16 17p13.1

BLYS, TALL1, TNF (ligand)


CD14 LPS-R Endotoxin, (LPS) 53/55 5q31.1 CD83 HB15 -/43 6p23 CCD158k† KIR3DL2, p140 HLA-A 140/70 19q13.4 CD257 superfamily, member 13b BCMA, TACI, BAFF-R 45 13q32-34
X-Hapten, Lewis X, LIGHT, TNF (ligand)
CD15 SSEA-1, 3-FAL
Selectins CHO CD84 p75, GR6 68-80/72-86 1q24 CD158z† KIR3DL7, KIRC1 19q13.4 CD258 superfamily, member 14
HVEM 28 19p13.3

CD94/CD159a heterodimer binds 12p12.3- TRAIL-R1, TNF-R


CD15s Sialyl Lewis X
E-selectin CHO CD85a ILT5, LIR3, HL9 HLA class I 19q13.4 CD159a NKG2A
to HLA-E 70/43
p13.1 CD261 superfamily, member 10a TRAIL 57 8p21

CD159c C type Lectin superfamily TRAIL-R2, TNF-R


CD15u 3’ sulpho Lewis X
P-selectin CHO CD85d* ILT4, LIR2, MIR10 HLA class I 110 19q13.4 NKG2C
member
40 12p13 CD262 superfamily, member 10b
TRAIL 60 8p22-p21

TRAIL-R3, TNF-R
CD15su 6 sulpho-sialyl Lewis X
L-selectin CD85j* ILT2, LIR1, MIR7 HLA class I 110 19q13.4 CD160 BY55, NK1, NK28 MHC class I 80/27 1q42.3 CD263 superfamily, member 10c TRAIL 65 8p22-p21

CD161 TRAIL-R4, TNF-R


CD16a FCRIIIA
IgG Fc 50-65/- 1q23 CD85k* ILT3, LIR5, HM18 HLA class I 60 19q13.4 NKR, NKRP1A 80/40 12p13 CD264 superfamily, member 10d
TRAIL 35 8p21

160-250/ TRANCE-R, TNF-R


CD16b FcgRIIIb IgG Fc 48 1q23 CD86 B7-2/B70 CD28, CD152 (CTLA-4) -/80 3q21 CD162 PSGL-1 CD62P, CD62L
110-120
12q24 CD265 superfamily, member 11a TRANCE 97 18q22.1
Lactosylceramide, TWEAK-R, TNF-R
CDw17 LacCer 150-160/120 CD87 uPAR uPA, Pro-UPA, Vitronectin 35-68/32-66 19q13 CD162R PEN5 Selectins 240/140 12q24 CD266 superfamily, member 12A
TWEAK 14 16p13.3

Integrin β2, CD11a,b,c 19q13.3- TACI, TNF-R superfamily,


CD18 β-subunit
CD11a,b,c 90/95 21q22.3 CD88 C5aR C5a/C5a(desArg), Anaphylatoxin 43/-
q13.4
CD163 M130, GHI/61, RM3/1 CD62L (L-selectin) 110 12p13.3 CD267 member 13B TALL1, BLYS, BAFF 32 17p11.2
CD21, CD81, CD225, Leu-13, Lyn, 45-100/ 19q13.2- BAFFR, TNF-R 22q13.1-
CD19 B4 Fyn, Vav, PI3-kinase >120/95 16p11.2 CD89 IgA Fc receptor, FcαR IgA1, IgA2
45-100 q13.4
CD164 MGC-24, MUC-24 160/80 6q21 CD268 superfamily, member 13C BAFF 25 q13.31
Lyn, LCK, Fyn, Cell surface protein: 11q12- 11q22.3- BCMA, TNF-R
CD20 B1, Bp35
28-30, 180-200, 50-60 KDa 33/35/37
q13.1
CD90 Thy-1 CD45, lck, fyn, P100 25-35/25-35
q23
CD165 AD2, gp37 37/42 CD269 superfamily, member 17 TALL1, BLYS, BAFF 27 16p13.1

12q13- ALCAM, KG-CAM, SC-1, 100-105/ NGFR, p75, TNFR


CD21 CR2, EBV-R, C3dR C3d, CD23, CD19, CD81, Leu13 130-145 1q32 CD91 α2M-R, LRP RAP, α2M, apoE, Lactoferrin, LDLs 600/-
q14
CD166 BEN, DM-GRASP
CD6, CD166, NgCAM 100-105 3q13.1 CD271 superfamily, member 16 NGF 75 17q21-q22

p72sky, p53/56lyn, SHP1,


CD22 BL-CAM, Lyb8, Siglec-2
PI3-kinase, CD45 140/130 19q13.1 CDw92 p70 70/70 9q31.2 CD167a DDR1, trkE, cak ShcA, FRS2, Collagens 120 6p21.3 CD272 BTLA B7H4 3q13.2

FceRII, B6, BLAST-2, Ras, Src, Erk, Actin, Calmodulin, 80-88/


CD23 Leu-20
IgE, CD21, CD11b,CD11c 50-45 19p13.3 CDw93 GR11 110/120 CD168 RHAMM, IHABP, HMMR
MAPKK, Hyaluronic acid
5q33.2 CD273 B7DC, PDL2 PD2 25 9p24.2

CD227, CD206, CD43,


CD24 BBA-1, HSA CD62P (P-selectin) 35-45 6g21 CD94 Kp43 HLA class I, NKG2-A, p39 70,30 12q13 CD169 Sialoadhesin, Siglec-1
α2,3-sialylated ligands
180/200 20p13 CD274 B7H1, PDL1 PD1 40 9p24

CD25 Tac antigen, IL-2Rα, p55 IL-2 55 10p15-


CD95 APO-1, FAS, TNFRSF6 CD178 (Fas ligand) 45,90,200/45 10q24.1 CD170 Siglec 5 Sialylated glycans 140 19q13.3 CD275 B7H2, ICOSL ICOS 60 21q22.3
p14
DPP IV ectoeneyme, ADA Adenosine deaminase, 3q13.13- CD171, Neurocan, Phosphocan,
CD26 binding protein Collagen, CD45
110 2q24.3 CD96 TACTILE 160/-
q13.2
CD171 L1CAM, NILE
Laminin
200-230 Xq28 CD276 B7H3 40 - 45 15q23-q24

19p13.2- BT3.1, B7 family:


CD27 T14, S152 CD70, TRAF5, TRAF2 110-120 12p13 CD97 BL-KDD/F12 CD55 (DAF) /28, 75-85
p13.12
CD172 SIRP-1α, MyD-1 65-110 20p13 CD277 Butyrophilin 3 56 6p22.1

CD28 Tp44, T44 CD80, CD86, PI3-kinase 90/44 2q33 CD98 4F2, FRP-1, RL-388 Actin 125/80,45 11q13 CD172b SIRPβ 50 20p13 CD278 ICOS B7-H2 56 2q33

Platelet GPIIa, β-1 Xp22.32,


CD29 integrin, GP
VCAM-1, MAdCAM-1 110-130 10p11.2 CD99 MIC2, E2 32/32
Yp11.3
CD172g SIRPg 45-50 20p13 CD279 PD1 PDL1 55 2q37.3

CD30 Ber-H2, Ki-1 CD153, TRAF1, 2, 3, 5 120/105 1p36 CD99R CD99 Mab restricted 32/32 9q22-q31 CD173 Blood group H type 2 170 CD280 TEM22, ENDO180 uPARAP 180 17q23.3

CD31 PECAM-1, Endocam CD38, CD31, GAGs, αvβ3 Integrin 130-140 17q23 CD100 SEMA4D CD45, Serine kinase 300/150 9q22-q31 CD174 Lewis Y 170 19p13.3 CD281 TLR1, TOLL-like receptor 1 Bacterial Lipoprotein 90 4p14

CD32 FCγRII Phosphatases, IgG 40 1q23 CD101 IGSF2, P126, V7 240/120 1p13 CD175 Tn CD282 TLR2, TOLL-like receptor 2 Peptidoglycan 85 4q32

17q23- CD175s
CD33 gp67 Sugar chains containing sialic acid 150/67 19q13.3 CD102 ICAM-2 LFA-1, CD11b/CD18, αLβ2 55-65/
q25
Sialyl-Tn (s-Tn) CD283 TLR3, TOLL-like receptor 3 dsRNA 100 4q35

HML-1, Integrin αE,


CD34 gp105-120 L-selectin, MadCAM-1 105-120 1q32 CD103 ITGAE
E-cadherin, Integrinβ7 175/150,25 17p13 CD176 TF Antigen 120-198 CD284 TLR4, TOLL-like receptor 4 LPS 85 9q32-q33

Laminins (I,II,IV,V), CD49F, 17q11-


CD35 CR1, C3b/C4b receptor C3b, C4b, iC3, iC4 160-250 1q32 CD104 β4 Integrin, TSP1180
integrin α6
205/220 CD177 NB1, HNA-2a 49-55/56-64 CD289 TLR9, TOLL-like receptor 9 CpG oligonucleotides 115-120 3p21.3
qter
9q33- CD178
CD36 GpIIIb, GPIV, PASIV Thrombospondin, Collagen I, IV, V 90 7q11.2 CD105 Endoglin TGF-β 1, TGF-β 3 180/90
q34.1
Fas Ligand DcR3, CD95 (Fas) 40/40 1q23 CD292 BMPR1A 50-58 10q22.3

19p13-
CD37 gp52-40 CD53, CD81, CD82, MHC II 40-52/40-52 q13.4 CD106 VCAM-1, INCAM-110 Integrin α4β 1, VLA-4 110/110 1p32-p31 CD179a VpreB CD179b, Ig µ heavy chain 16-18/ 22q11.22 CDw293 BMPR1B 50-58 4q22-q24
Available at BD

Available at BD

Available at BD

Available at BD
Endothelial Cell

Endothelial Cell

Endothelial Cell

Endothelial Cell
Dendritic Cell

Dendritic Cell

Dendritic Cell

Dendritic Cell
Macrophage/

Macrophage/

Macrophage/

Macrophage/
Granulocyte

Granulocyte

Granulocyte

Granulocyte
Epithelial Cell

Epithelial Cell

Epithelial Cell

Epithelial Cell
Erythrocyte

Erythrocyte

Erythrocyte

Erythrocyte
Stem Cell/

Stem Cell/

Stem Cell/

Stem Cell/
Monocyte

Monocyte

Monocyte

Monocyte
Precursor

Precursor

Precursor

Precursor
Platelet

Platelet

Platelet

Platelet
NK Cell

NK Cell

NK Cell

NK Cell
MW (kDa) MW (kDa) MW (kDa) MW (kDa)
B Cell

B Cell

B Cell

B Cell
T Cell

T Cell

T Cell

T Cell
Alternative Ligands and Gene Alternative Ligands and Gene Alternative Ligands and Unreduced/
Gene Alternative Ligands and Unreduced/
Gene
CD Name associated molecules
Unreduced/
Reduced
Locus CD Name associated molecules
Unreduced/
Reduced
Locus CD Name associated molecules Reduced
Locus CD Name associated molecules Reduced
Locus

CRTH2, PGRD2, G protein- 11q12-


CD38 ADP-ribosyl cyclase, T10 CD31, Hyaluronic acid 45/45 4p15 CD107a LAMP-1 100-120/110 13q34 CD179b λ5, 14.1, IGL5 CD179a, Ig µ heavy chain 22/ 22q11.23 CD294 coupled receptor 44 55-70 q13.3
ATPdehydrogenase, 95-105/
CD39 NTPdehydrogenase-1 ADP/ATP 80/80 10q24 CD107b LAMP-2 100-120/120 8p12-p11 CD180 RP105, Bgp95, Ly64 MD-1 95-105 5q12 CD295 LEPR Leptin 130-150 1p31

20q12- SEMA7A, JMH blood 15q22.3- CXCR1, (Formerly known ART1, ADP-
CD40 Bp50 CD154, CD40L, TRAP 85/48
q13.2
CD108 group antigen CD232, Tyrosine kinases 76/80
q23
CD181 as CD128a) IL-8
39 2q35 CD296 ribosyltransferase 1 37 11p15

CXCR2, (Formerly known ART4, ADP-ribosyltransferase 4; 12q13.2-


CD41 GPIIb, αIIb Integrin Fibrinogen, Fibronectin, vWF 135/120,23 17q21.32 CD109 8A3, E123 7D1 170/50 CD182 as CD128b)
40 2q33-q36 CD297 Dombrock blood group glycoprotein 38 q13.3
ATP1B3, Na K ATPase 3q23
CD42a GPIX vWF, Thrombin, CD42b,c,d 22/17-22 3q21 CD110 TPO-R, MPL, C-MPL TPO, JAK2 70-95/ 1p34 CD183 CXCR3, GPR9 IP10, Mig, I-TAC 40 Xq13 CD298 β3 subunit
50-60

17pter- PVRL1, HveC, PRR1, 11q23- 19p13


CD42b GPIbα vWF, Thrombin, CD42a,c,d 160/145
p12
CD111 Nectin1, HIgR Nectin3, Afadin gD /75 q24 CD184 CXCR4, NPY3R SDF-1, viral MIP-2 45 2q21 CD299 DCSIGN-related, L-SIGN CD209 antigen-like 45
HveB, PRR2, PVRL2, 19q13.2- 17q25.1
CD42c GPIbβ vWF, Thrombin, CD42a,b,d 160/24 22q11.21 CD112 Nectin2 PRR3, Afadin, CD112 64-72/64-72
13.4 CD185 CXCR5 45 11q23.3 CD300a CMRF-35H 60

CD42d GPV vWF, Thrombin, CD42a,b,c 82/82 3q29 CDw113 PVRL3, Nectin3, PRR3 83 CDw186 CXCR6 40 3p21 CD300c CMRF-35A 17q25.1

95-135/ 1p35-
CD43 Sialophorin, Leukosialin Hyaluronan
95-135 16p11.2 CD114 CSF3R, G-CSFR, HG-CSFR G-CSF, Jak1, Jak2 /130
p34.3 CD191 CCR1 MIP-1a, RANTES, MCP-3, MIP-5 39 3p21 CD300e CMRF-35L1
Hyaluronan, Ankyrin, Fibronectin, CSF-1, Phosphotyrosine binding 17p13.1
CD44 ECMRII, H-CAM, Pgp-1
MIP1β, Osteopontin
85/- 11p13 CD115 c-fms, CSF-1R, M-CSFR
proteins 150 5q33.2-33.3 CD192 CCR2 MCPs 40 3p21 CD301 MGL1, CLECSF14 38

Hyaluronan, Ankyrin, Fibronectin, 85-200/- Xp22.32 2q24.2


CD44R CD44v, CD44v9
MIP1β, Osteopontin
11p13 CD116 GM-CSFRα GM-CSF, CD131 70-85/
or Yp11.3
CD193 CCR3 45 3p21.3 CD302 DCL1 30
C-type Lectin, superfamily 12p13.2-
CD45 LCA, T200, B220, Ly5 p56lck, p59fyn, Src kinases 180-220/- 1q31-q32 CD117 c-KIT, SCFR SCF, MGF, KL, PI3-kinase 145/145 4q11-q12 CD195 CCR5 MIP-1a,1b,2, RANTES 62, 42 3p21 CD303 BDCA2 member 11 38 p12.3

CD45RA p56lck, p59fyn, Src kinases 220 1q31-q32 CD118 LIFR, gp190 IFN-α, IFN-β 190 CD196 CCR6 45 6q27 CD304 BDCA4 Neuropilin 1 140 10p12
MIP-3a
17q12- 19q13.4
CD45RB p56lck, p59fyn, Src kinases 220 1q31-q32 CDw119 IFNγR, IFNγRa IFNγ 80-95 6q23-q24 CD197 CCR7 (was CDw197) MIP-3b, SLC (6Ckine) 45
q21.2 CD305 LAIR1 40
17q12- 19q13.4
CD45RC p56lck, p59fyn, Src kinases 220 1q31-q32 CD120a TNFRI, p55 TNF, TRADD, TRAF, RiP, LTα 55 12p13.2 CDw197 CCR7, EBI1, BLR2 90 q21.2 CD306 LAIR2
1p36.3- 1q21
CD45RO UCHL-1 p56lck, p59fyn, Src kinases 180 1q31-q32 CD120b TNFRII, p75, TNFR p80 TNF, TRADD, TRAF, RiP, LTα 75 p36.2 CDw198 CCR8 50 3p22 CD307 IRTA2 100

CD46 MCP SCR2/3/4, Serum Factor 1 protease 52-58/64-68 1q32 CD121a Type 1 IL-1R IL-1α and IL-1β, IL1RA 75-85/75-85 2q12 CDw199 CCR9 43 3p21.3 CD309 VEGFR2, KDR, Flk1 VEGF 230 4q11-q12

3q13.1-
CD47 gp42, IAP, OA3, Neurophilin SIRP, CD61, Thrombospondin 45-60/50-55
q13.2
CD121b Type 2 IL-1R IL-1α and IL-1β, IL1RA 60-68/60-68 2q12-q22 CD200 OX2 40-45 3q12-q13 CD312 EMR2 90 19p13.1

3q13.1- IL-2, IL-15, CD25, CD132, Syk, 12p13.2-


CD47R MEM-133 120/-
q13.2
CD122 IL2Rβ
Lck, Jak1, Stat5
70-75/ 22q13.1 CD201 EPCR Protein C 49/25 20q11.2 CD314 NKG2D MIC A (MHC) 42 p12.3
Blast-1, Hulym3, BCM-1, 1q21.3- Xp22.3 or
CD48 OX-45
CD2, lck, fyn, CD229, CD244 45/45
q22
CD123 IL-3Rα IL-3, CD131 70/ Yp11.3 CD202b TEK/Tie2 Angiopoietin-1,2,and4 140 9p21 CD315 CD9P1 135 1p13.1

IL-4, IL-13, CD132, Jak1, Fes, 16p11.2- cAMP, NAD, Nucleoside


CD49a VLA-1α, α1 Integrin Collagen, Laminin-1 200/200 5q11.2 CD124 IL-4Rα
Stat6, IRS-2 140/
12.1 CD203c PDNP3, B10, PDI_, E-NPP3
phosphates
270/130,150 6q22 CD316 EWI2 63 1q23.1

CD49b VLA-2α, gpIa, α2 Integrin Collagen, Laminin 150/160 5q23-31 CD125 IL-5Rα IL-5, CD131 60/ 3p26-p24 CD204 MSR LDL, β-amyloid fibrils 220 8p22 CD317 BST2 29/33 19p13.2

145-150/
CD49c VLA-3α, α3 Integrin Laminin-5, Fn, Collagen 125,30 17q21.31 CD126 IL-6Rα IL-6, CD130 80/80 1q21 CD205 DEC-205 198 2q24 CD318 CDCP1 135 3p21.31

IL-7, CD132, fyn, lyn, Jak1, PI3- 1q23.1-


CD49d VLA-4α, α4 Integrin CD106, MAdCAM, Fibronectin 145/150 2q31-q32 CD127 p90, IL-7R, IL-7Rα
kinase, Lck 65-90/ 5p13 CD206 MMR Sialoadhesins and CD45 162-175/ 10p13 CD319 CRACC, SLAMF7 66 q24.1
12q11- IL-8Ra, CXCR1, (Tentatively 8D6 Antigen; FDC 19p13.3-
CD49e VLA-5α, α5 Integrin Fibronectin, Invasin, Fibrinogen 160/135,25
q13
CD128a renamed as CD181) IL-8, GRO 44-59/67-70 2q35 CD207 Langerin 2p13 CD320 8D6 p13.2
2p14- IL-8Rb, CXCR2, (Tentatively IL-8, GRO, NAP-2 1q21.2-
CD49f VLA-6α, α6 Integrin, gpIc Laminins, Invasin 150/125 CD128b 44-59/67-70 2q35 CD208 DC-LAMP LAMP 3q26.3-q27 CD321 JAM1 F11 receptor 32.35
q14.3 renamed as CD182) q21.3
19p13.3- Xq28
CD50 ICAM-3 LFA-1, Integrin αd/β2 110-140/-
p13.2
CD129 IL-9Ra IL-9
and Yq12 CD209 DC-SIGN ICAM-3, HIV gp120 44 19p13 CD322 JAM2 45 21q21.2

Integrin αv, VNR-α, Fibrinogen, Vitronectin,


CD51 150/124,24 2q31-q32 CD130 gp130 Oncostatin M, LIF, IL-6, IL-11, CNF 130-160/ 5q11 CDw210 CK IL-10 90
11q23.3,
CD324 E-Cadherin 120 16q22.1
Vitronectin-Rα MMP-2, vWF, TSP 130-160 21q22.11
CD123, CD125, CD116, JAK2,
CD52 CAMPATH-1, HE5 25-29/25-29 1p36 CD131 Common β subunit
Shc, Grb2
120-140/ 22q13.1 CD212 CK IL-12 -/110 19p13.1 CDw325 N-Cadherin 140 18q11.2

CD25, CD122, CD124, CD127,


CD53 OX-44 VLA-4, HLA-DR, other Tetraspans 32-42/- 1p31-p12 CD132 Common γ chain, IL-2Rγ
IL-9R, JAK3, JAK1, Syk, lck
65-70/- Xq13.1 CD213a CK IL-13 Xq24 CD326 Ep-CAM 40 2p21

19p13.3- AC133, PROML1, Prominin 1,


CD54 ICAM-1 LFA-1,Mac-1, Rhinovirus 90/95
p13.2 CD133 Heamtopoietic stem cell antigen
120/120 4p16.2 CDw217 CK IL-17 22q11.1 CDw327 Siglec6, CD33L Silylated glycans 19q13.3

CD55 DAF SCR, CD97, Echoviruses 55-70/80 1q32 CD134 OX40, TNFRSF4 OX40 ligand 35-50/ 1p36 CDw218a IL18Rα IL18Rα 70 CDw328 Siglec7 Silylated glycans 75 19q13.3

11q23-
CD56 Leu-19, NKH-1, NCAM NCAM-1, Heparin sulfate 140
q24
CD135 Flt3, FLK2, STK1 FL (Flt3 ligand) 130/155-160 13q12 CDw218b IL18Rβ IL18Rβ 70 CDw329 Siglec9 Silylated glycans 19q13.4

11q12- 8p11.2-
CD57 HNK1, Leu-7 L-selectin, P-selectin, Laminin 110-115
qter CDw136 MSP-R, RON, p158-ron MSP, HGFI, Shc, PLC-g 180/150,40 13p21.3 CD220 Insulin R Insulin 19p13.3 CD331 FGFR1 FGF 130 p11.1

CD58 LFA-3 CD2, LFA-2 55-70 1p13 CDw137 4-1BB, ILA 4-1BB ligand 85/39 1p36 CD221 IGF1 R IGFI, IGFII 15q25-26 CD332 FGFR2 FGF 115-135 10q26
1F5Ag, H19, Protectin, Syndecan-1, Heparan Collagen I, III, V, Fibronectin, Plasminogen, M6P, IGFII, LIF,
CD59 MACIF, MIRL, P-18 C8-α, C9, lck, fyn 18-25/19-25 11p13 CD138 sulfate proteoglycan TSP 70-92 2p24.1 CD222 M6P-R, IGFII-R Thyroglobulin, Cathapsin B,D,L, TGF_
250/300 6q26 CD333 FGFR3 FGF 115-135 4p16.3

GD3 5q35.1-
CD60a CD139 /209,228 CD223 LAG-3 MHC class II antigen 70 12p13 CD334 FGFR4 FGF 110 qter

CD60b 9-O-acetyl GD3 90-94/120 CD140a PDGF α receptor PDGF 160-180/- 4q11-q13 CD224 GGT GSH 27-68 22q11.23 CD335 NKp46, NCR1, Ly94 HA, CD3z 46 19q13.42

CD60c 7-O-acetyl GD3 CD140b PDGF β receptor PDGF 170-190/- CD225 Leu13 IFN-γ 17 11p15.5 CD336 NKp44, NCR2, Ly95 DAP12 44 6p21.1
5q31-q32
Thrombomodulin, 20p12-
CD61 GP IIIa, β3 Integrin Fibrinogen 90-110 17q21.32 CD141 Fetomodulin
Thrombin, Protein C, TAFI 75/105
cen CD226 DNAM-1, PTA1 LFA-1 65 18q22.3 CD337 NKp30, NCR3 Viral proteins 30 6p21.3

E-selectin, ELAM-1, Tissue factor, CD54, CD169, Selectins, Grb2,


CD62E LECAM-2
Sialyl Lewis x,a, CLA, CD162 115/97 1q22-q25 CD142 Thromboplastin, F3
Factor VIIa, Factor Xa/TFPI 45-47/45-47 1p22-p21 CD227 MUC1, PUM, PEM, EMA
β-Catenin, GSK-3b
300-700/ 1q21 CDw338 ABCG2 72 4q22

L-selectin, LAM-1, LECAM-1, ACE, Peptidyl dipeptidase ANG-1, Bradykinin 90,170/ 20p12.1-
CD62L MEL-14, Leu8, TQ1
CD34, GlyCAM-1, MAdCAM-1 74 1q23-q25 CD143 A, Kininase II 90,170 17q2 CD228 p97, gp95, MT 97 3q28-29 CD339 Jagged-1, JAG1 150 p11.23
P-selectin, GMP-140,
CD62P PADGEM
CD162, CD24 120/140 1q22-q25 CD144 VE-Cadherin, Cadherin-5 β-Catenin, p120 CAS, Plakoglobin 135/130 16q22.1 CD229 Ly9 SAP protein 100 1q22
LIMP, MLA1, gp55, NGA, 12-q12-
CD63 LAMP-3, ME491
VLA-3, VLA-6, CD81, CD9, PI4-kinase 40-60
q13 CDw145 25,90,110 CD230 Prion Protein (PrP) CD56, NCAM 33-37 20pter-p12

1q21.2- Muc 18, S-endo, MCAM,


CD64 FcγRI IgG 72
q21.3 CD146 Mel-CAM
113-118/130 11q23.3 CD231 TALLA-1, A15, TM4SF2 150/30-45 Xq11.4

Basigin, EMMPRIN, M6,


CD65 Ceramide, VIM-2 E-selectin CD147 OX47
50-60/55-65 19p13.3 CD232 VESP-R CD108, Viral semaphorin 200 12q23.3
200-260/ Glycophorin A, Ankyrin, 95-100
CD65s Sialylated-CD65, VIM2 Possibly E- or P-selectin CD148 HPTP-η, p260, DEP-1 200-260 11p11.2 CD233 Band 3, AE1, SLC4A1 Hemoglobin /95-110
17q12-q21

Tyrosine phosphatase CD45,


CD66a NCA-160, BGP CD62E, CD66c,e, Src kinases 140-180 19q13.2 CD150 SLAM, IPO-3
CD150
65-85/75-95 1q22-q23 CD234 DARC/Fy-glycoprotein IL-8, MGSA, RANTES, MCP-1 35-43 1q22-23

positive Abbreviations: Changes in Existing CD Entities


Printed in collaboration with Provisional “w” entities Changes in designation:
MW: molecular weight is shown as non-reduced/
now confirmed: CDw128A becomes CD181
Additional information on the positive upon activation
reduced where available
CDw197 becomes CD197 CDw128B becomes CD182
HLDA8 New CD molecules will CK/CKR: Cytokine/Chemokine Receptors
be published in special issues positive by cytoplasm staining
of Journal of Immunological
Methods and Journal of Cellular Immunology
negative
Please also visit us at For more details about BD Biosciences antibodies and their The next International HCDM (former HLDA)
antigens, please refer to the Technical Data Sheets supplied
www.bdbiosciences.com/humancdchart Meeting will be held in conjunction with the
* a CD nomenclature of detailing LIR/ILT genes (CD85) as well
as KIR genes (CD158) has been proposed based on the previous
on line at www.bdbiosciences.com/e_catalog.
following Conferences
for more information † CD designation of some members of this family and on the position
For additional information regarding each CD molecule,
please visit www.hlda8.org
of the genes on chromosome 19q13.4 from centromeric to • ISAC Congress, Quebec, Canada, May, 2006 - Session: HCMD: Successor to
telomeric loci. the HLDA Workshops - progress and planning
• ICI Congress, Rio de Janeiro, Brazil, August, 2007 - Session: Human Cell
Differentiation Molecules
available from BD Biosciences. Please contact Technical Services For research use only. Not for use in diagnostic or therapeutic procedures unless
or check our website at www.bdbiosciences.com for specific labeled as such. Not for Resale. Please contact Heddy Zola at
format and clone information.
[email protected]
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Company. ©2005 BD for more information.

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