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Drug Study: Adult: Induction: 40 MG

Propofol is a short-acting anesthetic used for induction and maintenance of general anesthesia. It works by rapidly redistributing from the brain to other tissues. Common adverse reactions include involuntary muscle movements, nausea, vomiting, headache, and fever. Nursing responsibilities include ensuring the patient is intubated and ventilated, closely monitoring vital signs, and discontinuing the infusion slowly to prevent agitation. Propofol must be administered carefully due to the risk of potentially fatal complications like apnea, bradycardia, and hypotension if not properly monitored.

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100% found this document useful (4 votes)
5K views2 pages

Drug Study: Adult: Induction: 40 MG

Propofol is a short-acting anesthetic used for induction and maintenance of general anesthesia. It works by rapidly redistributing from the brain to other tissues. Common adverse reactions include involuntary muscle movements, nausea, vomiting, headache, and fever. Nursing responsibilities include ensuring the patient is intubated and ventilated, closely monitoring vital signs, and discontinuing the infusion slowly to prevent agitation. Propofol must be administered carefully due to the risk of potentially fatal complications like apnea, bradycardia, and hypotension if not properly monitored.

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© Attribution Non-Commercial (BY-NC)
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DRUG STUDY

Prescribed and
Generic Name Recommended
Mechanism of Nursing
Brand Name Dosage, Frequency, Indication Contraindication Adverse Reaction
Action Responsibilities
Classification and Route of
Administration
Propofol: Induction and Propofol is a short-  Induction and Electroconvul- Involuntary muscle 1. Patient must be
acting anesthetic maintenance sive therapy, movements; nausea, Intubated and
maintenance
 Diprifol amp obstetrics. vomiting, headache, ventilated
given for induction of general
emulsion injection of general anesthesia anesthesia Sedation in fever; pain, burning 2. Monitor: HR, ECG,
Adult: Induction: 40 mg and maintenance of
 Diprivan amp children ≤16 yr. or stinging at Pulse Ox, BP
general anesthesia.  Sedation 3. Abrupt
 Diprivan pre- by injection or infusion Pregnancy, injection site.
Onset: 30 seconds. lactation. egg Potentially discontinuation of
filled syringe every 10 seconds.
Duration: 3-10 hypersensitivity, Fatal: Apnea, infusion may result in
 Fresofol 1% amp Usual dose: 1.5-2.5 minutes. soya lecithin bradycardia, rapid awakening with
 Hospira Propofol mg/kg. Maintenance: 4- Distribution: Extensi hypersensitivity; hypotension, agitation, anxiety
vial 12 mg/kg/hr or use cautiously in convulsions; 4. Discard tubing/bottle
vely redistributed from
intermittent bolus hypotensive anaphylaxis after 12 hours
 IV-Pro solution brain to other tissues;
injection of 20-50 mg.  patients 5. Do not use if
for IV infusion crosses the placenta emulsion appears
 Lipuro amp Child: >8 yr: Induction and enters breast separated
 Lipuro IV- dose of 2.5 mg/kg. milk. Protein-binding: 6. Maintain strict aseptic
infusion Maintenance dose: 9- 95% technique because
15 mg/kg/hr by IV Metabolism: Extensiv emulsion will support
rapid growth of
infusion or intermittent ely hepatic; converted
microorganisms.
bolus injection.  to water-soluble 7. If hypotension or
Elderly: Including sulfate and bradycardia occurs,
neurosurgical and glucuronide decrease or stop
debilitated patients: conjugates. Diprivan and monitor
Infuse at a rate of 20 Excretion: Urine (as BP & HR, notifyMD
metabolites); feces. 8. Document neuro
mg every 10 seconds. assessment on
Maintenance: 3-6 Elimination half-life:40
awakening (Ramsey
mg/kg/hr. Usual dose min (initial); 4-7 hr Level of Sedation
Scale)
DRUG STUDY

Prescribed and
Generic Name Recommended
Mechanism of Nursing
Brand Name Dosage, Frequency, Indication Contraindication Adverse Reaction
Action Responsibilities
Classification and route of
Administration
needed: 1-1.5 (terminal)
mg/kg.Intravenous

Sedation
Adult: In diagnostic
and surgical
procedures: Initially, 6-
9 mg/kg/hr by infusion
given for 3-5 minutes or
an alternative dose of
0.5-1 mg/kg by slow
injection over 1-5
minutes.
Maintenance: 1.5-4.5
mg/kg/hr infusion.
Reduce maintenance
dose by 20% for high-
risk patients needing
sedation. For ventilated
patients: 0.3-4 mg/kg/hr
by infusion. Monitor
lipid concentrations if
duration of sedation
lasts >3 days.

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