Famotidine (Pepcid) is an H2 receptor antagonist used to treat duodenal and gastric ulcers, GERD, and hypersecretory conditions. It works by competitively inhibiting histamine at H2 receptor sites, decreasing gastric acid secretion. Common side effects include headache, diarrhea, dry mouth, and rash. Nursing care involves assessing for abdominal pain or signs of bleeding, ensuring proper administration and storage of oral suspensions, and monitoring patients with kidney dysfunction.
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Famotidine
Famotidine (Pepcid) is an H2 receptor antagonist used to treat duodenal and gastric ulcers, GERD, and hypersecretory conditions. It works by competitively inhibiting histamine at H2 receptor sites, decreasing gastric acid secretion. Common side effects include headache, diarrhea, dry mouth, and rash. Nursing care involves assessing for abdominal pain or signs of bleeding, ensuring proper administration and storage of oral suspensions, and monitoring patients with kidney dysfunction.
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Generic Trade Classificati Dosage Mechani Indication Contraindi Side Effects Nursing Care
Name Name on sm of cation
action Famotidine Pepcid H2 ♥-adults: for Competi ♥Short-term Contraindi ♥CNS: ♥assess receptor acute therapy, tively treatment for cated in headache, patient for antagonist 40 mg P.O. once inhibits duodenal ulcer patients dizziness, fever, abdominal daily at bedtime action of hypertensi malaise, pain. Look for or 20 mg P.O. histamin ve to drug. paresthesia, blood in b.i.d. healing e on the vertigo. emesis, stool usually occurs H2 at ♥CV: flushing, or gastric within 4 weeks. receptor palpitations. aspirate. For sites of ♥EENT: orbital ♥oral maintenance parietal edema, tinnitus. suspension therapy, 20 mg cells, ♥G.I.: anorexia, must be P.O. once daily decreasi constipation, reconstituted at bedtime. ng diarrhea, dry and shaken gastric mouth, taste before use. ♥-adults: 40 mg acid ♥short-term perversion. ♥store P.O. daily at sectretio treatment for ♥Musculoskeleta reconstituted bedtime for 8 n. benign gastric l: bone & muscle oral weeks. ulcer pain. suspension -children ages 1 ♥Skin: acne, dry below 86oF to 16: skin. (30oC). 0.5mg/kg/day ♥Other: transient Discard after P.O. at bedtime irritation at I.V. 30 days. or divided b.i.d., site. up to 40 mg daily.
♥-adults: 20mg ♥pathologic
P.O. q 6 hours, hypersecretory up to 160 mg q conditions (such 6 hours. as Zollinger- Ellison syndrome)
♥-adults: 20mg ♥Hospitalized
I.V. q 12 hours patients who can’t take oral drug or who have intractable ulcers or hypersecretory conditions ♥-adults: 20 mg ♥Gastroesophage P.O. b.i.d. for up al reflux disease to 6 weeks. For (GERD) esophagitis caused by GERD, 20 to 40 mg b.i.d. for up to 12 weeks. -children ages 1 to 16: 1mg/kg/day P.O. divided twice daily up to 40 mg b.i.d.
♥-adults: 10mg ♥to prevent or
Pepcid AC P.O. treat heartburn 1 hour before meals to prevent symptoms, or 10 mg Pepcid AC P.O. with water when symptoms occur. Maximum daily dose is 20 mg. drug shouldn’t be taken daily for longer than 2 weeks. Adjust-a-dose: for patients with creatinine clearance below 50 ml/minute, give half the dose or increase dosing interval to q 36 to 48 hours.