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Park in Sons

Parkinson's disease is a progressive neurological disorder that affects movement. It develops as cells are destroyed in the substantia nigra, located in the brain stem, reducing dopamine levels in areas of the brain controlling movement. Dopamine deficiency is the hallmark of Parkinson's, as dopamine helps control movement and coordination. Loss of dopamine from destroyed cells in the substantia nigra negatively impacts nerves and muscles, causing major symptoms like tremors and difficulty moving.

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21 views2 pages

Park in Sons

Parkinson's disease is a progressive neurological disorder that affects movement. It develops as cells are destroyed in the substantia nigra, located in the brain stem, reducing dopamine levels in areas of the brain controlling movement. Dopamine deficiency is the hallmark of Parkinson's, as dopamine helps control movement and coordination. Loss of dopamine from destroyed cells in the substantia nigra negatively impacts nerves and muscles, causing major symptoms like tremors and difficulty moving.

Uploaded by

Mako Arizala
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Parkinson's Disease In-Depth Report

Background
Parkinson's disease (PD) is a slowly progressive neurological disorder that affects movement, muscle control, and balance. Parkinsons disease is part of a group of conditions called motor system disorders, which are associated with the loss of dopamine-producing brain cells. These dopamine-associated motor disorders are referred to as parkinsonism . Parkinson's disease (PD) is a slowly progressive neurological disorder that affects movement, muscle control, and balance. Parkinsons disease is part of a group of conditions called motor system disorders, which are associated with the loss of dopamine-producing brain cells. These dopamine-associated motor disorders are referred to as parkinsonisms.

Parkinson's Disease and Dopamine Loss


Parkinson's disease occurs from the following process in the brain:
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PD develops as cells are destroyed in certain parts of the brain stem, particularly the crescent-shaped cell mass known as the substantia nigra .

Parkinson's disease is a slowly progressive disorder that affects movement, muscle control, and balance. Part of the disease process develops as cells are destroyed in certain parts of the brain stem, particularly the crescent-shaped cell mass known as the substantia nigra. Nerve cells in the substantia nigra send out fibers to tissue located in both sides of the brain. There the cells release essential neurotransmitters that help control movement and coordination.
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Nerve cells in the substantia nigra send out fibers to the corpus stratia , gray and white bands of tissue located in both sides of the brain.

There the cells release dopamine , an essential neurotransmitter (a chemical messenger in the brain). Loss of dopamine in the corpus stratia is the primary defect in Parkinson's disease.

Dopamine deficiency is the hallmark feature in PD. It is one of three major neurotransmitters known as catecholamines , which help the body respond to stress and prepare it for the fightor-flight response. Loss of dopamine negatively affects the nerves and muscles controlling movement and coordination, resulting in the major symptoms characteristic of Parkinson's disease. Dopamine also appears to be important for efficient information processing, and deficiencies may also be responsible for problems in memory and concentration that occur in many patients.

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