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SR - No. Name of Topic No.: Reported Method of Analysis For Losartan As A Single Component

This document provides an index and overview of analytical methods and results for analyzing the drug Losartan using UV-Visible spectrophotometry. It describes using two methods: a zero order spectrum method and first order derivative spectroscopy method. For each method, it lists tables and figures showing standard calibration curves, optical characteristics, validation of the methods, analysis of Losartan standards and tablets, and recovery studies. The objective is to develop and validate methods for quantitative analysis of Losartan as a single component using UV-Visible spectrophotometry.

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Rema Wed
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14 views

SR - No. Name of Topic No.: Reported Method of Analysis For Losartan As A Single Component

This document provides an index and overview of analytical methods and results for analyzing the drug Losartan using UV-Visible spectrophotometry. It describes using two methods: a zero order spectrum method and first order derivative spectroscopy method. For each method, it lists tables and figures showing standard calibration curves, optical characteristics, validation of the methods, analysis of Losartan standards and tablets, and recovery studies. The objective is to develop and validate methods for quantitative analysis of Losartan as a single component using UV-Visible spectrophotometry.

Uploaded by

Rema Wed
Copyright
© Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Sr.no.

Name Of Topic

Page no.

Introduction Introduction to analytical chemistry UV-Visible Spectrophotometry Method of single component analysis using UV-Visible spectrophotometer Validation of analytical method Instrument UV-Visible Spectrophotometry(Double Beam) Losartan Drug Profile
Reported method of analysis for Losartan as a single component

1 1 5 9

14

Ia b IIa B

Objective of work Plan of work Methodology Zero order spectrum method:Experimental Result First order derivative Spectroscopy: Experimental Result Summary And Conclusion References

INDEX FOR TABLE


Table no. Name Of Table Page No.

Losartan
Zero order spectrum method

1 2 3 4 5
Result:

Standard calibration table for Losartan Optical characteristics and other parameters Statistical validation by zero order spectrum method Analysis of standard Losartan Assay of the tablet

6
7

Analysis of tablet Formulation


Statistical validation by order spectrum method

8 9

Recovery studies Statistical validation of recovery study

First order derivative spectroscopy 10 Standard calibration table for Losartan

11 12 13 14
Result

Optical characteristics and oter parameters Statistical validation of calibration curve Analysis of standard Losartan Assay of the tablet

15 16 17 18

Analysis of tablet formulation Statistical validation by first order derivatives spectrum method Recovery studies Statistical validation of recovery study

Summary and conclusion

19
20

Optical characteristics and other parameters Statistical validation method

INDEX FOR FIGURE


Fig. No. Name of Figure Page No.

Drug Profile: 1 Mechanism of action of Losartan Zero Order spectrum method


2 Zero order spectrum of Losartan

Calibration curve of Losartan

First order derivative spectroscopy 4 First order derivative spectrum of Losartan 5 Calibration curve of Losartan and First order derivative spectrum

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