Post Basic (Biophysics)
Post Basic (Biophysics)
Nursing Year - I BIOCHEMISTRY AND BIOPHYSICS Course Code: PBN103 L-2 T-0, P-0, C-2 Course Description: This course introduces the basic principles of Biochemistry and Biophysics related to Nursing. OBJECTIVES At the end of the course, the student will: 1. Identify the basic principles of Biochemistry and Biophysics. 2. Synthesize the knowledge of these principles in various Nursing situations. Section A: Biochemistry Course Contents Unit I Introduction: Importance of Biochemistry in Nursing. Study of cell and its various components. Unit II Water and Electrolytes: Water Sources, property & functions in human body. Water and fluid balance. Electrolytes of human body, functions, sources. Unit III Enzymes Mechanism of action Factors affecting enzyme activity Diagnostic applications Precautions for handling specimens for enzyme estimation. Digestion and absorption of carbohydrates, proteins and fats
Various factors influencing the digestion and absorption, mal-absorption syndrome. Unit IV Carbohydrates: Catabolism of carbohydrates for energy purposes. Mitrochondrial oxidation and oxidation phosphorylation. Fats of glucose in the body. Storage of glucose in the body, glycogenesis, glycogenolysis and neoglucogenesis, blood glucose and its regulation. Glucose tolerance test, hyperglycemia, hypoglycemia, glycemia. Unit V Protein: Amino acids, hormones. Essential amino acids. Biosynthesis of protein in the cells. Role of nucleic acid in protein synthesis. Nitrogenous constituents of urine, blood, their origin urea cycle, uric acid formation, gout. Plasma proteins and their functions. Unit VI Fat: Biosynthesis of fats and storage of fats in the body. P.B. Nursing Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 10 of 47 Role of liver in fat metabolism. Biological importance of important lipids and their functions Cholesterol and lipoprotein Sources, occurrence and distribution Blood level and metabolism Ketone bodies and utilization. Inter relationship in metabolism and cellular control of metabolic processes. Section B: Biophysics Course Contents
Unit I Introduction: Concepts of unit and measurements. Fundamental and derived units. Units of length, weight, mass, time. Unit II Vector and scalar motion, speed, velocity and acceleration. Unit III Gravity: Specific gravity, centre of gravity, principles of gravity. Effect of gravitational forces on human body. Application of principles of gravity in Nursing. Unit IV Force, work, energy: their units of measurement. Type and transformation of energy, forces of the body, static forces. Principles of machines, friction and body mechanics. Simple mechanics lever and body mechanics, pulley and traction, incline plane, screw. Application of these principles in Nursing. Unit V Heat: Nature, measurement, transfer of heat. Effects of heat on matter. Relative humidity, specific heat. Temperature scales. Regulation of body temperature. Use of heat for sterilization. Application of these principles in Nursing. Unit VI
Light: Laws of reflection. Focusing elements of the eye, defective vision and correction, use of lenses. Relationship between energy, frequency and wavelength of light. Biological effects of light. Use of light in therapy. Application of these principles in Nursing. Unit VII Pressures: Atmospheric pressure, hydrostatic pressure, osmotic pressure. P.B. Nursing Revised Syllabus Applicable w.e.f. Academic Session 2011-12 (22022012) Page 11 of 47 Measurements of pressures in the body Arterial and venous blood pressures Ocular pressure Intracranial pressure Application of these principles in Nursing. Unit VIII Sound: Frequency, velocity and intensity. Vocalization and hearing. Use of ultrasound. Noise pollution and its prevention. Application of these principles in Nursing. Unit IX Electricity and electromagnetism: Nature of electricity, voltage, current, resistance and their units. Flow of electricity in solids, electrolytes, gases and vacuum. Electricity and human body. ECG, EEG, EMG, ECT.
Pace makers and defibrillation. Magnetism and electricity. M.R.I. Scanning, C.A.T scan. Unit X Atomic energy: Structure of atom, isotopes and isobars. Radioactivity: Use of radioactive isotopes. Radiation protection units and limits, instruments used for detection of ionizing radiation. XRays. Unit XI Principles of electronics: Common electronic equipments used in patient care. PRACTICUM Experiments and tests should be demonstrated wherever applicable. Reference Books 1. Eastham Duncan Robert, Biochemical Values in Clinical Medicine, John Cought and Sons Ltd, 1977. 2. Chandlish J K, Lecture Notes on Biochemistry, Blackwell Scientific Publications, 1984. 3. Klein S. Israel and Ordan James, Human Biochemistry, Mosby Co., 1958. 4. Varley Harold, Practical Clinical Biochemistry, CBS Publishers and Distributers, 1988, New Delhi.