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Plummer 2

This document contains an abstract submission for a presentation by Dr. Nigel Plummer titled "The Developmental Origins of Modern Disease – Are We Programmed to Develop Disease In the Womb?". The abstract discusses evidence that sub-optimal environmental and nutritional conditions in the womb can program chronic diseases like heart disease and cancer through non-genetic means. These diseases often manifest later in adult life. The presentation will explore this concept of fetal disease programming, its causes, and its effect on subsequent risk of various diseases. It will also discuss opportunities for nutritional interventions to prevent adverse programming and potentially chronic disease.

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67 views

Plummer 2

This document contains an abstract submission for a presentation by Dr. Nigel Plummer titled "The Developmental Origins of Modern Disease – Are We Programmed to Develop Disease In the Womb?". The abstract discusses evidence that sub-optimal environmental and nutritional conditions in the womb can program chronic diseases like heart disease and cancer through non-genetic means. These diseases often manifest later in adult life. The presentation will explore this concept of fetal disease programming, its causes, and its effect on subsequent risk of various diseases. It will also discuss opportunities for nutritional interventions to prevent adverse programming and potentially chronic disease.

Uploaded by

rbtakemoto
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC or read online on Scribd
You are on page 1/ 2

AANP ABSTRACT SUBMISSION

Contact:
Penny Gregorio
490 Elgin Mills Road East, Toronto, Ontario
905-508-2050 ext. 2233
[email protected]

Speaker:
Dr. Nigel Plummer PhD
3 Christchurch Road, Unit 3, South Wales, UK
Tel: 011441-639-825100
Fax: 011441-639-825101
[email protected]

Oral presentation, 90 minutes (60 if accepted for Breakfast presentation)

I. TITLE
The Developmental Origins of Modern Disease – Are We Programmed to Develop Disease In the
Womb?

II. DESCRIPTION
There is compelling evidence to support the revolutionary concept of non genetic, foetal and
neonatal programming of many chronic diseases which are often only manifest decades later in
adult life. Many of these disease development phenomena are now strongly linked to sub-optimal
environmental and nutritional conditions in the womb.

III. FULL ABSTRACT


There is now compelling evidence to support the revolutionary concept of non genetic, foetal and
neonatal programming of many chronic diseases such as coronary heart disease and cancer, which are
often only manifest decades later in adult life. Many of these disease development phenomena are now
strongly linked to sub-optimal environmental and nutritional conditions in the womb, and as such can be
modified with the potential for altered disease outcome.

In this lecture the evidence for the concept of foetal disease programming, its causes and also its effect on
subsequent risk of developing diseases as diverse as pre-eclampsia, coronary artery disease, and breast
cancer will be explored.

Furthermore, the opportunity for nutritional and other interventions to negate adverse programming
occurring possibly represents the most profound and unexplored mechanism for chronic disease
prevention to come to light for many years.

1
IV. EDUCATIONAL OBJECTIVES

a. Link between metabolic programming in preconceptual, foetal and neonatal periods and the
risk of subsequent disease later in life

b. The role of sub-optimal nutritional and environmental conditions in the preconceptual, foetal
and neonatal periods which lead to adverse programming

c. Therapeutic options available to prevent adverse programming or help to re-write write the
programme later in life

VI. PRESENTATION OUTLINE:

I. Etiology & Genetic Inheritance – but are we missing something?


a. The Fetal Link to Heart Disease- Compelling Evidence
b. The Developmental Origins of Disease (Barker Hypothesis)
c. Diseases now associated with Birth Weight

II. Evidence based research


a. Fetal/Neonatal programming:
b. Summary Developmental Origins of Health and Adult Disease
III. Nutritional Support

a. Is there an Optimal Nutritional Program?


I. Fetal
II. Neonatal Period
b. Summary

Pharmacy: minor mention of insulin reactivity and glucose tolerance, Th1, Th2.
Target audience: Physicians, medical practitioners, Obstetricians and midwives, Chinese and Eastern
medicine practitioners, Homeopaths, Nutritionists, herbalists, botanists, Researchers and scientists,
Educators, Students
Presentation should be submitted for CE credits

Bio:
Dr. Nigel Plummer Ph.D has his doctorate in microbial physiology from the University of Surrey
(London) and has worked at Pfizer in antibiotic research and development. His research on the use of
normal flora in the prevention and treatment of genito-urinary candidiasis has won him numerous
awards. Dr. Plummer continues his solid commitment to research throughout his career in collaboration
with research institutes and universities within the UK and Europe, developing an extensive knowledge
specializing in probiotics, natural antimicrobials and fish oils.
Dr. Plummer’s research involves the role of probiotics in:
 modulation of the gastrointestinal microbiota and the prevention of antibiotic resistance post
antibiotic therapy
 prevention of Clostridium difficile diarrhoeal infections
 the control of IBS symptoms
 prevention of allergy – modulation of the neonatal intestinal microbiota to minimize the
incidence of atopic eczema and subsequent asthma development.

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