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Bricanyl

Terbutaline is a bronchodilator used to treat asthma and COPD that works by stimulating beta-2 receptors, causing bronchodilation, increased heart rate, and other effects. It can also be used to stop preterm labor by intravenous infusion. Special precautions are needed in elderly patients, pregnant or breastfeeding women, and those with heart or thyroid conditions. Common side effects include nervousness, hypertension, nausea and hypokalemia. Nurses should monitor patients for signs of worsening bronchospasm, changes in contractions or fetal heart rate during labor, and hypoglycemia.

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2K views

Bricanyl

Terbutaline is a bronchodilator used to treat asthma and COPD that works by stimulating beta-2 receptors, causing bronchodilation, increased heart rate, and other effects. It can also be used to stop preterm labor by intravenous infusion. Special precautions are needed in elderly patients, pregnant or breastfeeding women, and those with heart or thyroid conditions. Common side effects include nervousness, hypertension, nausea and hypokalemia. Nurses should monitor patients for signs of worsening bronchospasm, changes in contractions or fetal heart rate during labor, and hypoglycemia.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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Brand Name: Brethaire, Brethine, Bricanyl

Generic Name: Terbutaline


Indications: Used as a Bronchodilator in reversible airway obstruction due to Asthma or
COPD. Unlabeled Use: Used to arrest preterm labor.
Drug Classification: Bronchodilator – Beta-adrenergic Agonist
Mechanism of Action:
A Beta-adrenergic agonist that results in the accumulation of cyclic Adenosine
Monophosphate (cAMP).
Results of increased levels of camp at Beta-adrenergic receptors include:
Bronchodilation, CNS and Cardiac Stimulation, Diuresis, Gastric Acid Secretion.
Relatively selective for Beta2 (Pulmonary) Receptors.
Dosage: Bronchodilation
PO (Adults): 2.5-5mg tid, at 6-hr intervals.
PO (Children 12-15 yr): 2.5 mg tid, at 6-hr intervals.
SC (Adults): 0.25mg, may repeat in 15-30 min (not to exceed 0.5mg in 4hr).
Inhaln (Adults and Children > 12yr): 2 inhalations q 4-6 hr (200 mcg/spray).
Tocolysis (Arrest of Preterm Labor)
PO (Adults): 2.5mg q 4-6 hr until delivery.
IV (Adults): 10mcg/min infusion, increase by 5mcg/min q10 min until contractions
stop (not to exceed 80mcg/min). After contractions have ceased for 30 min,
decrease infusion rate to lowest effective amount and maintain for 4-8 hr after
contractions have stopped.
Special Precaution: Elderly Patients; Pregnancy, Lactation, or Children <12 yrs. Old;
Cardiac disease; Hypertension; Hyperthyroidism; Diabetes Mellitus; Glaucoma;
Pregnancy near term; Excessive use of inhalers
Pregnancy Risk Category: B
Adverse Reactions: CNS: Nervousness, Restlessness, Insomnia, Tremor, Headache, and
Anxiety
CV: Hypertension, Arrhythmias, Angina, Tachycardia, Palpitations, and Pulmonary
Edema
GI: Nausea, Vomiting
F and E: Hypokalemia
Contraindications: Hypersensitivity to adrenergic amines or any ingredients in
preparations.
Form: Tab 2.5mg x 100’s, 500’s; Extended-release tab 5mg x 100’s; Syr 1.5mg/5ml x
60ml x 6’s, 120ml; Nebuhaler 1’s; Refill canister 0.25mg x 200 doses x 1’s, 200
(continuation Brethaire, Brethine, Bricanyl)
doses x 10’s; Nebuliser solution 5mg/2ml x 20’s, 50’s; Inhaler 0.25mg/dose x 200
doses; Turbuhaler 500mcg/dose x 100 doses; Amp 0.5mg/ml x 10’s; Nebuchamber;
Expectorant Syr 120ml, 6 x 60ml
Nursing Responsibilities:
 Bronchospasm: assess blood pressure, pulse, respiratory pattern, lung sounds,
and character of secretions prior to and after treatment. Cardiovascular effects
are increased with parenteral use.Observe patient for apperance of drug
tolerance and rebound bronchospasm.
 Preterm Labor: Monitor maternal pulse and blood pressure, frequency and
duration of contractions, and fetal heart rate. Notify physicial if contractions
persist or increase in frequency or duration or if symptoms of maternal or fetal
distress occur. Maternal side effects include tachycardia, palpitations, tremor,
anxiety, and headache. Assess maternal respiratory statusfor symptoms of
pulmonary edema. Monitor mother and neonate for symptoms of hypoglycemia
and mother for hypokalemia.
 Lab Test Considerations: Monitor maternal serum glucose and electrolytes. May
cause hypokalemia and hypoglycemia. Monitor neonate’s serum glucose, as
hypoglycemia may also occur in neonate.

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