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Levetiracetam Brand Indication Dosage Form Cost/Packing: Adult and Adolescent 16 Years 500mg BID

This document summarizes information on 5 brands of the anti-epileptic drug levetiracetam. It provides the brand name, indication, dosage forms, dosing recommendations and cost for each. The dosages vary depending on the condition being treated, whether used as monotherapy or add-on therapy, and patient age and weight. All require gradual titration to the maximum recommended daily dose to improve tolerability.

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Mark Prads
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327 views

Levetiracetam Brand Indication Dosage Form Cost/Packing: Adult and Adolescent 16 Years 500mg BID

This document summarizes information on 5 brands of the anti-epileptic drug levetiracetam. It provides the brand name, indication, dosage forms, dosing recommendations and cost for each. The dosages vary depending on the condition being treated, whether used as monotherapy or add-on therapy, and patient age and weight. All require gradual titration to the maximum recommended daily dose to improve tolerability.

Uploaded by

Mark Prads
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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LEVETIRACETAM

BRAND INDICATION DOSAGE FORM COST/PACKING


1. Ivetra (Torrent) Adjunctive therapy in the
treatment of partial
seizures with or without
secondary generalization
Adult and adolescent
>16 years 500mg BID,
may be increased to
1500mg BID. Dose
titration can be made in
500mg increments or
decrements.

Elderly and patients with
renal impairment
individualized dosage
1000 film-coated
tablet 1000mg

250 film-coated
tablet 250mg

500 film-coated
tablet 500mg
60s (P4945.50/pack)


60s (P1283.78/pack)


60s (P2538.27/pack)
2. Letram (Hetero drugs) Adjunctive therapy in the
treatment of partial
seizures with or without
secondary generalization
Monotherapy adult and
adolescent >16 years
initially 250mg BID
increased to 500mg BID
after 2weeks. May be
further increased by
250mg BID twice weekly.
Max: 1500mg BID

ADD-ON THERAPY
adult and adolescent
>12 years >50kg initially
500mg BID, may be
increased up to 1500mg
BID. Dose may be titrated
by increment/ decrement
of 500mg BID 2-4 times
weekly.

4-17 years <50kg initially
10mg/kg BID, may be
250mg film-
coated tablet

500mg film-
coated tablet
100s


100s
increased up to 30mg/kg
BID. Dose
increment/decrement
should not exceed
10mg/kg BID 2x weekly.

Children >50kg adult
dose
3. Vexlev (VE Pharma) Adjunct in the treatment of
partial seizures with or
without secondary
generalizations
Adult >16 years 250mg,
increase in increments of
500mg every 2weeks.
Max: 1500mg.

Pedia (20kg body
weight) 4-16 years
10mg/kg, increased
increments of 10mg/kg
every 2 weeks to
30mg/kg; 6months-
4years 10mg/kg,
increased increments of
10mg/kg every 2weeks to
25mg/kg; 1 to <6 months
7mg/kg, increased
increments of 7mg/kg
every 2weeks to
21mg/kg.

Myoclonic seizures adult
and ped >12 years
500mg, increased by
500mg every 2weeks to
1500mg.

250mg film-
coated tablet

500mg film-
coated tablet
30s


30s
Primary generalized
tonic-clonic seizures
adult >16 years 500mg,
increased by 500mg
every 2weeks to 1500mg;
Pedia 6-16 years
10mg/kg, increase in
increments of 10mg/kg
every 2weeks to
30mg/kg. All doses to be
taken BID
4. Keppra
(GlaxoSmithKline)
Monotherapy in the
treatment of partial onset
seizures with or without
secondary generalization in
patients > 16 years with
newly diagnosed epilepsy.

Adjunctive therapy in the
treatment of partial
seizures with or without
secondary generalizations
in adults and children >4
years with epilepsy

Myoclonic seizures in
adults and adolescents >12
years with juvenile
myoclonic epilepsy

Primary generalized tonic-
clonic seizures in adults and
children >4 years with
idiopathic generalized
Monotherapy adult and
adolescent >16 years
initially 250mg BID,
increased to 500mg BID
after 2 weeks. May be
further increased by
250mg BID 2x weekly.
Max: 1500mg BID.

Add on therapy adult
(>18 years) & adolescent
12-17 yrs >50kg initially
500mg BID, may b
increased up to 1500mg
BID. Dose may be titrated
by increment/decrement
of 500mg BID 2-4x
weekly.

Children and adolescent
>50kg adult dose; 4-
17yrs <50kg initially
10mg/kg BID, may be
1000mg film-
coated tablet

250mg film-
coated tablet

500mg film-
coated tablet

500mg/5mL
infusion
concentration

100mg/mL oral
solution
60s (P7187.00/pack)


60s (P1977.00/pack)


60s (P3952.00/pack)


Vial x 5mL x 5 x 1s
(P30477.70/box)


300mL x 1s
(P1927.80/bottle)
epilepsy increased up to 30mg/kg
BID. Dose
increment/decrement
should not be >10mg/kg
BID 2x weekly; children
<25kg start the
treatment with
100mg/mL oral solution.
5. Levit (InnoGen
Pharmaceuticals)
Adjunctive therapy in the
treatment of partial
seizures with or without
secondary generalization

Second-line drug in
generalized tonic clonic
seizures, myoclonus
including juvenile
myoclonic epilepsy and
atonic or tonic seizures
Initially 1g on day 1 in 2
divided doses. May be
increased in increments
of 1g every 2-4 weeks up
to max of 3g daily.
1g film-coated
tablet

500mg film-
coated tablet
60s (P4260.00/pack)


60s (P2100.00/pack)

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