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PAtho Cholecystitis

This document discusses the pathophysiology of gallstones. It identifies age 40 and above, female gender, genetic predisposition, and high estrogen levels as predisposing factors. Obesity, rapid weight loss, lack of physical activity, oral contraceptive use, and pregnancy are listed as precipitating factors that can cause bile to become supersaturated with cholesterol and calcium, leading to gallstone formation. Untreated gallstones can cause obstruction of the cystic duct and common bile duct, resulting in sharp abdominal pain, jaundice, gallbladder distention, and inflammation known as cholecystitis.

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Janry-Mae Escobar Tumaneng
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186 views2 pages

PAtho Cholecystitis

This document discusses the pathophysiology of gallstones. It identifies age 40 and above, female gender, genetic predisposition, and high estrogen levels as predisposing factors. Obesity, rapid weight loss, lack of physical activity, oral contraceptive use, and pregnancy are listed as precipitating factors that can cause bile to become supersaturated with cholesterol and calcium, leading to gallstone formation. Untreated gallstones can cause obstruction of the cystic duct and common bile duct, resulting in sharp abdominal pain, jaundice, gallbladder distention, and inflammation known as cholecystitis.

Uploaded by

Janry-Mae Escobar Tumaneng
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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I.

PATHOPHYSIOLOGY
PREDISPOSING FACTORS:

PRECIPITATING FACTORS:

Age 40 and above


Female
Genetic Predisposition
High Estrogen Levels

Bile must become


supersaturated with
cholesterol and calcium

The solute precipitate from


solution as solid crystals

Gallstones

Obesity
Rapid weight loss and Diet
Lack of Physical Activity
Use of Oral Contraceptives
Pregnancy

Crystals must come together


and fuse to form stones

Obstruction of the cystic duct and common bile duct

Sharp pain in the right part of


abdomen

Jaundice
Distention of the
gallbladder

Proliferation of bacteria

Venous and lymphatic


drainage is impaired

Localized cellular irritation or


infiltration or both take place

Inflammation of gall bladder

CHOLECYSTITIS

Risk factor
o
o
o
o
o
o

Heredity
Obesity
Rapid Weight Loss, through diet or surgery
Age Over 60
Female Gender
Diet-Very low calorie diets, prolonged fasting, and lowfiber/high-cholesterol/high-starch diets.

Areas of ischemia may occur

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