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European IPR Helpdesk

Fact Sheet
Intellectual property in Biotechnology
June 2014
1.

Intellectual Property and Biotechnology ........................................................ 2

1.1

The different forms of Intellectual property in Biotechnology ........................... 3

1.2

Patents on biotechnological inventions.......................................................... 4

2.

Biotechnology and innovation in Europe........................................................ 8

2.1

The innovation cycle .................................................................................. 8

2.2

The European actors of the innovation cycle in Biotechnology .........................10

2.3

Open innovation: cooperation between SMEs, public research institutes and

larger companies ......................................................................................10

3.

Practical advice: How to use biotechnology patent indicators ..........................11

3.1

How to find biotechnology patents? .............................................................11

3.2

How to get innovation indicators from biotechnology patents? ........................13

Useful information ................................................................................................16

Introduction
Biotechnology is generally defined as the application of science and technology
to living organisms, as well parts, products and models thereof, to alter living or
non-living materials for the production of knowledge, goods and services1. This
definition is deliberately broad and covers all modern biotechnology but also
many other traditional or borderline activities. Taken all together, these activities
belong to what is commonly called Life Sciences.
Biotechnology is a field where technology advances rapidly but returns on
investments may be slow. For this reason, it is important for public research
organisations and enterprises to protect the innovation that they generate with
Intellectual Property Rights (IPR), which provide a basis for return on investment
in research and development, by granting monopoly rights for a certain period of
time to their owners.

A framework for biotechnology statistics, OECD, Paris, 2005.

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This fact sheet aims at giving a brief overview of:

1.

The different forms of Intellectual Property (IP) that can be relevant in

biotechnology and focuses more specifically on patents;
The role of biotechnology in innovation in Europe; and
How to use patent information for innovation indicators.

Intellectual Property and Biotechnology

Biotechnology is usually subdivided into three sectors that may overlap, namely:

Healthcare biotechnology or red biotechnology which plays an important role

in drug discovery (insulin, erythropoietin, etc.) and today is improving
outcomes for patients and addressing unmet medical needs for the future;

Agriculture biotechnology or green biotechnology that is used to enhance

plants in order to improve their resistance to disease, tolerance for herbicides
or difficult environment conditions, or to achieve higher yields with less
inputs (water, fertilizers, etc.);

Industrial biotechnology or white technology, representing the third wave in

biotechnology, because it follows innovation in the health and agricultural
areas; this sector encompasses the application of biotechnology-based tools
to traditional industrial processes (bioprocessing) and the manufacturing of
bio-based products (biofuels, bio-plastics and bio-based chemicals). In this
technology enzymes and/or micro-organisms, such as fungi, yeast, bacteria
(also referred as biocatalysts), are used to make intermediate and endproducts more efficiently, reduce environmental impacts of processes and
products and/or enable the creation of new products from renewable
resources.

In principle, the results generated by the research activity of these different

sectors can be protected by IPR. Thus all actors involved in a biotechnologybased industry should have a basic understanding of the different types of
Intellectual property (IP) and related rights granted by the system, in terms of:
What results can be protected;
The IP rights at their disposal;
What these rights entail;
How long these rights last.

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1.1

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The different forms of Intellectual property in Biotechnology

The IP created by biotechnology companies that can take a number of different

forms, consisting of vaccines, seeds, plants, medical devices and software, but
also brands and domain names, among others. Most of these different assets
may attract more than one form of IP protection. In the biotechnology sector the
most relevant form of IP are patents, although other forms are also applicable
and used in practice. The table 1 below2 summarises the different forms of IP
protection which can be used to protect biotechnology innovation.

Patents

Trade marks
Registered
designs

Isolated polynucleic acids, peptides and polypeptides, enzymes,

microorganisms, viruses, vectors, antibodies, probes, vaccines,
compositions, expression systems, cell lines, plants, seeds,
transgenic organisms, methods for preparation or use of the
above;
medical devices
Words/name, computer icons, graphical designs, multimedia
elements or use of the above;
medical devices
Medical devices, biochemical, biophysical or bio-electrochemical
apparatus

Trade secrets
/ know-how

Laboratory notebooks, design workbooks, customer information,

documented internal processes, data exclusivity on clinical data
generated for therapeutic approval

Plant
breeders' or
plant variety
rights

Plant varieties, propagating and harvesting material from plant

varieties

Domain
names

Web addresses

Table 1

The deployment of IPR will depend on a number of factors, including the actors
area of specialisation, structure, anticipated activities, and whether it is engaged
in commercial activity.

The table has been elaborated based on the Biotechnology Intellectual Property management
manual, Spruson & Ferguson, 2008.

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SHORT REMINDER ON IP
PATENT
A patent is a legal document, through which a right is granted for an invention, a product or a
process that provides a new way of doing something or offers a new technical solution to a
problem. A patent provide exclusive rights for a fixed period of time in exchange for public
disclosure of the invention. A patent enables the patent owner/holder to exclude unauthorised
third parties from making, using, selling, offering for sale or importing for those purposes a
product, a process, or a product obtained by a patented process for the term of the patent.

TRADE MARK

COPYRIGHT and RELATED RIGHTS

A Trade Mark is a distinctive sign that

identifies certain goods or services as those
produced or provided by a specific person or
enterprise. Trademarks may be obtained for
the brand name of a particular product or
service.

provide the right to exclude others from

copying creative works including software
but do not cover ideas, procedures, methods of
operation or mathematical concepts as such.
Copyrights may apply to the literature
developed in relations to a product

REGISTERED DESIGN RIGHTS

DOMAIN NAME

are awarded to the developer as IPR that

protects the visual design of an item, which
are not functional. Industrial design concerns
more the aspect and aesthetic of the device,
also in Life Sciences and biotechnology field.

A domain name is the main address of a web

site. More precisely, a domain name consists of
one or more parts that are conventionally
concatenated, and delimited by dots, such as
something.com. Domain names are susceptible
to be protected as distinctive signs, if
identifying the source of a product or service.

PLANT BREEDERS RIGHTS

TRADE SECRET and KNOW-HOW

are also known as plant variety protection

rights. They are rights granted to the
breeder of a new variety of plant which is
distinct, uniform and stable. They provides
for the breeder exclusive control over the
propagating material (including seed,
cuttings, divisions, tissue culture) and
harvested material (cut flowers, fruit,
foliage) of a new variety for a number of
years.

are valuable forms of IP. The term confidential

business information know-how and trade
secrets are often used interchangeably but
strictly speaking, the two latter are a subset of
confidential information in the context of
business, commerce or trade. Trade secrets
are valuable as long as they are kept secret
which can be done through confidentiality or
non-disclosure agreements. In fact, although
considered as other forms of IP, no rights are
granted by the system3.

1.2

Patents on biotechnological inventions

As in other technological fields, biotechnology patent are used to protect

technical innovation, including the way it works, how it is made and even how it
is used. They grant its owner the exclusive right to prevent others from making,
using, selling, offering for sale, or importing an invention without his consent, on
a defined territory for a limited period of time4.

For a deeper analysis on the relevance of trade secrets and know-how, see the European IPR
Helpdesk fact sheet on Confidential business information, available in the library.
4
In Europe, the protection lasts 20 years from the first filing of the patent application.

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The rationale behind the patent protection for biotechnology inventions is related
to the fact that:

Patents give the possibility to the inventor to recoup the development

costs of a new biotech product;
Patents require the disclosure of the new technology for the benefit of
society. Putting the new technology into the public domain inspires further
innovation and development by competing companies, much like scientific
publications spawn new discovery efforts and new lines of inquiry. Thus
patents are a very rich source of technical information.

Like other patents, biotechnology patents also contain:

A description of the invention itself with specific details and the

advantages that this invention brings in comparison with the known state
of the art, and examples;
A set of claims, which define the matter for which protection is sought. In
biotechnology claims are mostly concerned with:
o Product claims
o Use claims
o Method of production claims

What characterises biotechnology patent is that they are defined as patents

belonging to a defined list of Patent Classification codes.
To be patentable biotechnological inventions need to meet the same criteria as
inventions in other technology fields.
For an invention to be patentable it:

Must be an invention and not a discovery, and not belong to the

list of exclusions;
E.g. discoveries, scientific theories and mathematical methods.
The discovery of natural substances, such as the sequence or partial
sequence of a gene, for instance, are not patentable because, without
a description of the technical problem and the solution to it they are
intended as technical teaching, which is not regarded as invention
(Art.52(2)(a) EPC).

Must be new (not belonging to the state of the art);

Must involve an inventive step (not easily conceivable by any
person having an expertise in the relevant discipline);
Must be capable of industrial application (to be used in the
industry).

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1.2.1. What is patentable and what is not

The European Patent Convention5 stipulates several exclusions from patentability
of certain inventions, applicable mainly in the biotech field.
These exclusions are the following:

Any invention whose commercial exploitation may considered immoral

or against the ordre public and which concerns in particular:
(a) Processes for cloning human beings;
(b) Processes for modifying the germ line genetic identity of human
beings;
(c) Uses of human embryos for industrial or commercial purposes;
(d) Processes for modifying the genetic identity of animals which are likely
to cause them suffering without any substantial medical benefit to man
or animal, and also animals resulting from such processes6.

Plant and animals variety or essentially biological processes for the

production of plants and animals. A process for the production of plants or
animals is essentially biological if it consists entirely of natural phenomena
such as crossing and selection7. Note that plant varieties can be protected
under the Community plant variety rights system in the EU, which is based
on the International Union for the Protection of New Varieties of Plants
(UPOV Convention), and provides a sui generis form of IP protection
specifically adapted to the process of plant breeding and developed with
the aim of encouraging breeders to develop new varieties of plants.

Methods for treatment of the human or animal body, i.e. methods for
treatment by surgery or therapy, and diagnostic methods practised
on the human or animal body. The philosophy is that medical doctors
should never be prevented from doing what their Hippocratic Oath obliges
them to do, i.e. practice medicine ethically.

See article 53 EPC.

See rule 28 EPC.
7
See rule 26 EPC. The Enlarged Board of Appeal of the EPO clarified this exclusion and interpreted
the meaning of essentially biological processes in the Broccoli I case G 2/07 by stating that: A
non-microbiological process for the production of plants which contains or consists of the steps of
sexually crossing the whole genomes of plants and of subsequently selecting plants is in principle
excluded from patentability as being "essentially biological" within the meaning of Article 53(b)
EPC. Such a process does not escape the exclusion [] merely because it contains, [], a step of a
technical nature which serves to enable or assist the performance of the steps of sexually crossing
the whole genomes of plants or of subsequently selecting plants. If, however, such a process
contains [] an additional step of a technical nature, which step by itself introduces a trait into the
genome or modifies a trait in the genome of the plant produced, [], then the process is not
excluded from patentability under Article 53(b) EPC.
6

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However, according to Rules 26 and 27 of the EPC:

Biotechnological inventions are defined as inventions which concern a

product consisting of or containing biological material or a process by
means of which biological material is produced, processed or used;

Biological material means any material containing genetic information

and capable of reproducing itself or being reproduced in a biological
system. This definition covers living organisms and also DNA;

Biotechnological inventions should also be patentable if they concern:

(a) biological material which is isolated from its natural environment or
produced by means of a technical process even if it is previously
occurred in nature;
(b) plants or animals if the technical feasibility of the invention is not
confined to a particular plant or animal variety;
(c) a microbiological or other technical process or a product
obtained by means of such a process other than a plant or animal
variety (Rule 27 EPC).

Together with the EPC, the Directive 98/44/EC on the legal aspects of
biotechnological inventions, implemented by all member states, provides the
basis for deciding on patentability of biotechnology applications at the EPO and
puts greater focus on ethical considerations.
Besides the EPC provisions, the Directive rules out:

The patenting of the entire human body in all its developmental phases;
Processes for modifying the germ line genetic identity of human beings
and the use of human embryos for industrial or commercial purposes.

Table 2 below8 summarises what can be patentable and not patentable in the
biotechnology field:
What is patentable?

What is not patentable?

Genes and nucleic acid molecules

e.g.: - disease related genes for diagnosis
- antisense,
- siRNA molecules for therapy

Sequences without a known function

e.g.: - Expressed Sequence Tags (ESTs)
resulting from automated sequencing

Proteins
e.g.: - insulin
- erythropoietin for therapy
- cellular receptors for drug screening

Genetically modified animals which is

suffering without any substantial
medical benefit
e.g.: - a genetically modified animal which is
solely used to test cosmetics

Table two has been reproduced from Patents on life? European law and practice for patenting
biotechnological inventions, European Patent Office, Munich, Germany, 2009.

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Enzymes
e.g.: - protease for washing powder
- cellulose-degrading enzymes for the
production of bio-fuels
Antibodies
e.g.: - for cancer treatment
- pregnancy tests
- diagnostics
Virus and virus sequences
e.g.: - hepatitis C virus
- HIV for blood testing
- development of vaccines and therapies
Cells
e.g.: - haematopoietic stem cells for the
treatment of leukaemia

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Plant varieties as such

e.g.: - Golden delicious apples
Animal varieties
e.g.: - Holstein cattle

Human embryos

Processes which necessarily involve the

use and destruction of human embryos

Micro-organisms
e.g.: - bacteria for bioremediation
- yeast for food production

Human germ cells (sperm, oocytes)

Transgenic Plants
e.g.: - herbicide resistant soybean
- golden rice which accumulate provitamin A
- drought-resistant plants
- algae and genetically modified yeast for
capturing CO2 from the atmosphere

Human-animal chimera

Transgenic Animals
e.g.: - disease models for research such as the
genetically modified oncomouse
- donor animals for xenotransplantation
- dairy animals which produce
medicaments in milk

2.

Table 2

Biotechnology and innovation in Europe

Biotechnology makes a significant contribution to the modernisation of Europes

industry sectors. Its broad range of high-tech applications is increasingly playing
a role in enhancing the EU market competitiveness, raising economic growth and
improving the welfare of European citizens. Biotechnology has become the
driving force of radical changes in innovation processes in various sectors.
2.1

The innovation cycle

Innovation can be described as a cycle - innovation cycle - because it is in fact

a continuous process of discovery, validation development, registration and
commercialisation, leading to the creation of value which can be reinvested in
further innovations.

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The innovation cycle in the biotechnology sector is complex, expensive and long,
and success is uncertain. The diagram below9 summarises the key phases of this
cycle. Societal needs motivate researchers in public institutes and private
companies to come up with creative new ideas and concepts. Such research
often leads to the development of new products. In many sectors, these
products are then subjected to regulatory approval, which is itself followed by
commercialisation (either directly or indirectly by licensing agreements). These
newly commercialised products provide benefits to enterprises, researchers,
and society at large, but part of the sales revenue is ultimately reinvested into
new research.
Societal needs drive
demand: e.g. illness,
agricultural problems,
environmental challenges
or production needs

Economic returns
necessary to
reinvest to research

Benefits:
Economic returns
Tax revenues
Employment
Better products

Creative concepts
& Research:
Copyright in lab
notebooks
Know-how and trade
secrets protection
Existing inventions as
patents
Confidentiality security

IP in the
Innovation
Cycle

Commercialisation:
Packaging as designs,
trade marks and copyright
Licensing agreements
Patent claims on new
products
Copyright in product data
and patients information
Patent terms
extension is also

possible

Development:
Parental seeds lines,
plant breeding books,
field trial data as trade
secrets
Plant varieties protection
Laboratory, clinical trial
testing results confidential
as a trade secret
Devices for drugs as
patents, designs and
copyright

Regulatory approval:
Regulatory data
protected through data
protection rules and as
trade secrets

The diagram has been elaborated based on the EuropaBio brochure How intellectual property
rights promote innovation and create economic and societal value, available here.

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Considering IPR in the innovation cycle ensures that the actors (public, private
developers) are rewarded for their efforts and enable them to (re)invest in new
technology and product R&D. Therefore, it is important that the fruits of the R&D
investments are effectively protected and managed through a vigilant IP strategy
because IP is a driving force behind continued innovation.
2.2

The European actors of the innovation cycle in Biotechnology

According to the Organisation for Economic Co-operation and Development

(OECD)10, four groups can be distinguished among the firm active in
biotechnology and firms active in biotechnology R&D in the business sector:

Biotechnology firms which use biotechnology to produce goods or

services and/or to perform biotechnology R&D;
Biotechnology R&D firms which perform biotechnology R&D;
Dedicated biotechnology firms which devote at least 75% of their
production of goods and services, or R&D, to biotechnology;
Dedicated biotechnology R&D firms which devote at least 75% of their
total R&D to biotechnology.

But also added to this list can be:

2.3

Public-sector biotechnology R&D. University or Public Research

Institutes inventions are often made with less effort than a proof of
concept or prototype (they use IP to take the innovations developed in
their research laboratory to the market when a new outstanding
technology is discovered).
Plant breeders that are using biotechnology R&D in addition to and in
combination with traditional plant breeding methods (marker assisted
breeding, new breeding techniques, etc.)
Open innovation: cooperation between SMEs, public research
institutes and larger companies

Innovative products do not necessarily stem from an applied research activity.

Open innovation is gaining more and more importance, mainly among SMEs,
because this collaborative process permits companies that cannot afford to rely
entirely on their own research to use IP from other organisations, under
preferential conditions. Indeed, innovation is not only a matter of seeking IP
protection, but also of understanding how IP is operating within the innovation
cycle and the business strategy of companies, in order to develop competitive
advantage through the use of IP.
Academia and other public research institutes: their role is essential in open
innovation. Many universities have technology transfer offices which deal with

10

Future prospects for industrial Biotechnology, OECD, Paris, 2011

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these matters and generate significant additional resources for new R&D
activities.
SMEs: their role cannot be underestimated. Thus, in industrial biotechnology and
in pharmaceutical sectors, SMEs are the key players in the initial development of
many innovations and, in agricultural biotechnology, collaborations with
universities allow for major innovations. Moreover SMEs are often created as
university start-ups to build on a promising innovation, which could attract the
interest of larger companies in having it licensed or even permanently assigned.
In this way access to venture capital for start-ups is facilitated in the research
phase.
Larger companies: develop their own products but collaborate also with
universities or public research institutes for the successful development of a
product. Collaborations are often set up as licensing agreements in return for
payment of royalties. In some cases, ownership of IP rights is transferred, or
SMEs are acquired.

3.

Practical advice: How to use biotechnology patent indicators

Patents are important in all technology fields but probably even more important
for new and specialised fields such as biotechnology because they can contain
information that may not be captured by other indicators. In fact, according to
the OECD, patent information is essential for small companies because it allows
them to come up with new ideas based on previous inventions and develop them
into a viable product11. For this reason, those involved in this sector should be
familiar with patent databases and how to use them.
3.1

How to find biotechnology patents?

Patents in biotechnology are available, as other patents, using two main kinds of
tools:

11

Free-of-charge databases. Organisations such as the EPO, the WIPO as

well as some National Patent Offices provide free access to patent
information on their websites. For example, Google as a private initiative
offers access to the full US Patents database;
Commercial patent databases, managed by private companies which
charge for their use. They provide access to databases covering the whole
patent literature or sectoral patent information;
Patent alerts of Branch Organisations. For example, the German
association of plant breeders (BDP) publishes a monthly overview of new
(published/granted) patents in green biotechnology.

A framework for biotechnology statistics, cited.

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Examples of patent databases:

Free-of-charge (available on the web): Google Patents; Espacenet;
USPTO; Patent Scope; Eurasian Patent Organisation
Commercial: Questel-Orbit; Matheo Software patent; STN; Thomson
innovation; Derwent;
A patent document contains several sections which can be analysed in order to
connect the patent rapidly and easily to a relevant technology. The most relevant
of these sections are:

Title of the invention;

Abstract describing the invention;
List of claims;
Patent classification codes.

These latter codes organise and index the technical content of a patent document
and, in the case of biotechnology, patents are defined as patents belonging to a
specific/defined list of patent classification codes.
The patent classification codes assigned by patent examiners during the patent
examination process help to group inventions according to technical area and so
to identify patents from a certain technological area. They are organised
hierarchically and divided in sections and subsections.
The main patent classification systems relevant to organisations wishing to
develop their technologies in the EU are: the International Patent Classification
(IPC), the European Patent Classification (ECLA) and the Cooperative Patent
Classification (CPC). Such systems provide for a hierarchical system of language
independent symbols for the classification of patents and utility models according
to the different areas of technology.
It can be noted that, in the biotechnology sector, the majority of patents are
classified in the International Patent Classification sub-classes C12M to C12S.
Note however that it is extremely difficult to capture all biotechnology patents
using only those two sub-classes.
Generally speaking, the broader the technology field, the more difficult it is to
identify the corresponding classes, as they will be spread across different higher
level categories, and possibly mixed with other technologies which are not of
interest.
Thus for instance, although the list of classes for biotechnology is concentrated in
section A, C and G of the IPC, certain patents in the biotechnology field might be
found in sections B, D and E but are mixed with other technology domains from

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which they cannot be separated (e.g. bioinformatics can be assigned to G06F but
this class includes other computer-related technologies)12.

Examples of IPC codes for patents in the biotechnology field:

A01H1/00, A01H4/00, A61K38/00, A61K39/00, A61K48/00, C02F3/34,
C07G(11/00,13/00,15/00), C07K(4/00, 14/00, 16/00, 17/00, 19/00),
C12M, C12N, C12P, C12Q, C12S, G01N27/327, G01N33/(53*13, 54*,
55*, 57*, 68, 74, 76, 78, 88, 92)14.
For emerging technologies, a specific category or class might not yet be
incorporated into the patent classification systems, which makes it difficult to
identify patents related to these technologies afterwards. Therefore to select
patents related to specific technological domains, one can either look at the IPC
classes and subclasses, and/or search for appropriate key words within the text
fields of the patent document. Such a method might exclude, or include, patents
that are not relevant for a specific domain, but it makes it possible nonetheless
to provide a relatively good picture of innovation in the same technology field.
3.2

How to get innovation indicators from biotechnology patents?

Based on the information available in a patent document, it is possible to build

innovation indicators. These very important indicators are generally obtained
by interpreting information provided in the patent bibliography notices (also
called bibliographic references), although parts of them may be also retrieved via
publication and business information.
They are generally built by cross-referencing the information present in what are
the called bibliographic fields of the patent notices. Some indicators of particular
relevance are for instance:

The evolution of a firms activities (information extracted from the Patent

assignee and Priority date bibliographic fields);
The companys fields of activity (from the Patent assignee / IPC codes
bibliographic fields);
The evolution of the interests for national markets (from the Patent
family / Priority year bibliographic fields).

Generating indicators based on patents can help organisations to exploit

empirical information to estimate factors that affect technological advance and
successful commercialisation:
12

For more information on patent searching, see the European IPR Helpdesk fact sheet on How to
search for patent information, available in the library.
13
The asterisks indicate that those IPC codes also include subgroups up to one digit. For example
in addition to the code G01N33/53, the codes G01N33/53(1), G01N33/35(2), etc., are included.
14
A framework for biotechnology statistics, cited.

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To measure the implication of R&D (or other) activity with respect to a

technology;
To assess one or more competitor organisations and their technology
development activities (patent survey);
To analyse the technology field and estimate the technological advance.

Indicators issued from patents can also help you to inform organisations when it
comes to take strategic decisions on key issues. Accordingly, Porter and
Cunningham15 suggest for instance five applications of patent information which
can be useful to inform any technological sector:

Technological emphasis
Technological share
Rate of technology growth
Patent quality
National profile

More specifically, patent information in the biotechnology field can be used to

perform a:

Patent survey for a biotechnology company,

Patent landscape for a product, a pathology, a device, etc.

Examples of innovation indicators for the biotechnology sector:

Patent survey for a biotechnology
company
Publication trends
Distribution by date
Distribution of patent family sizes
Geographical distribution of patent filings
Trend of geographical distribution of patent
filings
Geographical distribution of patent filings
Assignee collaboration network

Citations
Patent family having most citations
Patent families having most self-citations
Forward/backward citations map
Evolution of patents citing companys
patents

Patent landscape for a pathology

Patent landscape overview

Geographic breakdown of patent filings

Main patent applicants
Main inventors
Main academic patent applicants
Legal status of patent filings
Countries of filings for main patent applicants
Patent applicant network
Main IPC sub-classes
Backward citations map
Main routes of administration claimed
Main mechanisms of action claimed
Technology breakdown of patent filings

Natural products and traditional medicine

Geographic breakdown of patent filings

Main patent applicants
Main inventors
Countries of filings for main patent applicants
Patent applicant IP network
Main IPC sub-classes

15

A. L. Porter and J. Cunningham, Tech Mining: Exploiting new technologies for competitive
advantage - Generating and presenting innovation indicators, p. 249-288, New York, 2005.

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Legal

Main IP attorneys
Legal status of patent filings
Patent granted by patent office
Time for Company to grant US patents
Distribution of total claims per US patents
European patent opposition
Main patent reassignment
Actual or expected expiration date

Inventors
Top and last inventors
Evolution of the number of new inventors
Main inventor collaborations

Technology
Main 20 IPC codes
Evolution of top 15 IPC codes
Main patent type filed
Evolution of main patent types
Main pathologies claimed
Evolution of main pathologies claimed
Main routes of administrations claimed
Evolution of main routes of administration
Main mechanisms of action claimed
Evolution of main mechanisms of action
claimed

Main IPC classes

Backward citations map
Main routes of administration claimed
Main natural products claimed
Main mechanisms of action claimed

Formulation

Geographical breakdown of patents filings

Main patent applicants
Main inventors
Countries of filing for main patent applicants
Patent applicant IP network
Main IPC sub-classes
Main IPC classes
Backward citations map
Main routes of administration claimed
Main mechanisms of action claimed

New chemistry entity

Geographical breakdown of patent filings

Main patent applicants
Main inventors
Countries of filing for main patent applicants
Patent applicant IP network
Main IPC sub-classes
Main IPC classes
Backward citations map
Main routes of administration claimed
Main mechanisms of action claimed

Device

Geographical breakdown of patent filings

Main patent applicants
Main inventors
Countries of filing for main patent applicants
Patent applicant IP network
Main IPC sub-classes
Main IPC classes
Backward citations map
Main devices claimed

Table 316

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This table has been adapted from the information provided in the patent surveys 2013 Acna and
Viropharma, conducted by Knowmade and available here.

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The European IPR Helpdesk

www.iprhelpdesk.eu

Useful information

A framework for biotechnology statistics, OECD, Paris, 2005:

http://www.oecd.org/science/biotech/aframeworkforbiotechnologystatistic
s.htm

Biotechnology Intellectual Property management manual, Spruson &

Ferguson, 2008: http://www.spruson.com/biotechnology-intellectualproperty-management-manual/

Fact sheet on Confidential business information:

http://www.iprhelpdesk.eu/Fact-Sheet-How-to-Manage-ConfidentialBusiness-Information

Fact sheet on How to search for patent information:

http://www.iprhelpdesk.eu/Fact-Sheet-How-to-Search-for-PatentInformation

Patents on biotechnology European law and practice, European Patent

Office, Munich, Germany 2014:
http://documents.epo.org/projects/babylon/eponet.nsf/0/50e49b8a1ca124
37c12575ad00372678/$FILE/biotechnology_brochure_en_2014.pdf

Patents on life? European law and practice for patenting biotechnological

inventions:
http://documents.epo.org/projects/babylon/eponet.nsf/0/50e49b8a1ca124
37c12575ad00372678/$FILE/biotechnology_brochure_en.pdf

How intellectual property rights promote innovation and create economic

and societal value: http://www.europabio.org/how-intellectual-propertyrights-promote-innovation-and-create-economic-and-societal-value

Future prospects for industrial Biotechnology:

http://www.oecd.org/sti/biotech/futureprospectsforindustrialbiotechnology
.htm

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The European IPR Helpdesk

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This Fact Sheet has been initially developed under a previous edition of the European IPR Helpdesk (20112014). At that time the European IPR Helpdesk operated under a service contract with the European
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