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Problem Set 1

This document contains 14 genetics problems involving monohybrid and dihybrid crosses, sex-linked inheritance, codominance, incomplete dominance, and lethal alleles. The problems cover a variety of inheritance patterns and genetic concepts, including determining gametes, performing Punnett squares, identifying parental and filial genotypes, and explaining observed phenotypic ratios.

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Serene Sheikh
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Download as PDF, TXT or read online on Scribd
0% found this document useful (0 votes)
215 views

Problem Set 1

This document contains 14 genetics problems involving monohybrid and dihybrid crosses, sex-linked inheritance, codominance, incomplete dominance, and lethal alleles. The problems cover a variety of inheritance patterns and genetic concepts, including determining gametes, performing Punnett squares, identifying parental and filial genotypes, and explaining observed phenotypic ratios.

Uploaded by

Serene Sheikh
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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PCB 3063

Problem Set 1
1. Determine the types of gametes produced by each of the following individuals:
a. Aa
b. AaBb
c. AABb
d. AaBBCc
2. Use the Punnett square to determine the genotypes in the progeny of each of the
following crosses:
a. Dd x Dd
b. AaBB x AaBB
c. CcEE x CCEe
3. In guinea pigs, rough coat (R) is dominant over smooth coat (r). A rough coated
guinea pig is bred to a smooth one, giving eight rough and seven smooth progeny
in the F1 generation.
a. What are the genotypes of the parents and their offspring?
b. If one of the rough F1 animals is mated to its rough parent, what progeny would
you expect?
4. In maize, a dominant allele A is necessary for seed color, as opposed to colorless (a).
Another gene has a recessive allele w that results in waxy starch, as opposed to
normal starch (W). The two genes segregate independently. Use branch diagrams
to determine the phenotypes and relative frequencies of offspring from each of the
following crosses?
a. AaWw x AaWw
b. AaWW x AaWW
c. AaWw x Aaww
5. Both John and Cathy have normal vision. After 10 years of marriage to John, Cathy
gave birth to a color-blind daughter (color blindness is an X-linked recessive
trait). John filed for divorce, claiming that he is not the father of the child. Is John
justified in his claim of non-paternity? Explain your answer. Give the genotypes
of John, Cathy and the child.
6. If traits R1 and R2 exhibit incomplete dominance over each other, what will be the
phenotypic ratio in the progeny of the cross R1R1 x R1R2 ?

7. In shorthorn cattle, coat color may be red, white, or roan (an intermediate color). The
following data were obtained from various crosses:
red x red
white x white
red x white
roan x roan

=> all red


=> all white
=> all roan
=> 1/4 red: 1/2 roan: 1/4 white

a. How is coat color inherited?


b. What are the genotypes of parents and offspring in each cross?
8. If traits LM and LN exhibit codominance relative to each other, what will be the
phenotypic ratio in the progeny of the cross LMLN x LMLN ?

9. Bar is an X-linked mutation in Drosophila that exhibits incomplete dominance. Flies


that are homozygous for Bar have bar-shaped eyes. Heterozygous flies have beanshaped eyes (an intermediate phenotype).
a. What will be the outcome of a cross between a normal female and a bar-eyed
male?
b. Use the Punnett square to determine the genotypes and phenotypes of the F2
generation.
10. In a rare species of frog, red color (Y) is dominant over yellow color (y, a null allele).
The character is autosomal. The cross YY x Yy produced over 100 frogs: 96% red
and 4% yellow. Which complication of Mendelian genetics can explain this
outcome?
a. recessive lethality of the y allele
b. codominance
c. incomplete dominance
d. incomplete penetrance
e. variable expressivity
11. In foxes, two alleles of a single gene, P and p, may result in lethality (PP), platinum
coat (Pp), or silver coat (pp).
a. Is the P allele behaving as dominant or recessive in causing lethality?
b. Is the P allele behaving as dominant or recessive in causing platinum coat color?
c. What ratios are obtained when platinum foxes are interbred?

12. In a species of duck, normal females are XY. There is an X-linked allele (E1) that
results in animals with only one eye (pictured above). The normal phenotype
results from the wild-type allele (E), which is also necessary for survival. Use the
Punnet square to determine the genotypic and phenotypic ratios in the progeny of
a cross between a one-eyed male and a normal female.
13. Normal chupacabra males are XY. The g allele is X-linked recessive lethal.
Heterozygous individuals have gray hair instead of the normal black hair. Use the
Punnett square to determine the outcome of a cross between a normal male and a
gray female.
14. Use branch diagram to calculate the phenotypic ratios in the progenies form the
following crosses involving production of H-substance and blood type:
a. hh IAIA x Hh IAIB
b. Hh IAIB x Hh IAIB
c. Hh IBIB x hh IBIO

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