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Ofloxacin Drug Study

The document discusses the drug ofloxacin, including its generic and brand names, classification, indications, contraindications, adverse effects, drug interactions, and nursing considerations. It provides details on ofloxacin's therapeutic actions, indications for lower respiratory tract infections, gonorrhea, skin infections, urinary tract infections, and more. Adverse effects include headache, nausea, vomiting, and rash. Drug interactions and nursing considerations are also outlined.

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3K views2 pages

Ofloxacin Drug Study

The document discusses the drug ofloxacin, including its generic and brand names, classification, indications, contraindications, adverse effects, drug interactions, and nursing considerations. It provides details on ofloxacin's therapeutic actions, indications for lower respiratory tract infections, gonorrhea, skin infections, urinary tract infections, and more. Adverse effects include headache, nausea, vomiting, and rash. Drug interactions and nursing considerations are also outlined.

Uploaded by

Cheezy Bread
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Ofloxacin Drug Study

In making a Drug Study, the following elements must be present: Generic Name and the
Brand name (not all brands, just the brand used by the patient), Action, Indication,
Pregnancy Category, Drug Classification, and Contraindication, Adverse Effect, Drug
interaction and Nursing Consideration/Intervention. Most clinical instructors preferred this
to be in a long bond paper in printed or handwritten with paper in landscape.

Ofloxacin
Brand Name: Floxin, Ocuflox
Pregnancy Category C
Drug classes: Antibiotic, Fluoroquinolone
Therapeutic actions
Bactericidal; interferes with DNA replication in susceptible gram-positive and
gram-negative bacteria, preventing cell reproduction.
Indications
Lower respiratory tract infections caused by Haemophilus influenzae,
Streptococcus pneumoniae
Acute, uncomplicated urethral and cervical gonorrhea due to Neisseria
gonorrhoeae, nongonococcal urethritis, and cervicitis due to Chlamydia
trachomatis, mixed infections due to both
Skin and soft tissue infections due to Staphylococcus aureus,
Staphylococcus pyogenes, Proteus mirabilis
Urinary tract infections due to Citrobacter diversus, Enterobacter
aerogenes, Escherichia coli, Klebsiella pneumoniae, Pseudomonas
aeruginosa
Primary treatment of PID (oral)
Prostatitis due to E. coli
Treatment of ocular infections caused by susceptible organisms (ophthalmic
solution)
Orphan drug use: treatment of bacterial corneal ulcers
Otic: otitis externa, chronic suppurative otitis media, acute otitis media
Contraindications
Contraindicated with allergy to fluoroquinolones, pregnancy, lactation.
Adverse effects

Headache, dizziness, insomnia, fatigue, somnolence, depression, blurred


vision,
Nausea, vomiting, dry mouth, diarrhea, abdominal pain, Elevated BUN, AST,
ALT, serum creatinine and alkaline phosphatase; decreased WBC, neutrophil
count, Hct,
Fever, rash, photosensitivity
Drug Interactions:
Decreased therapeutic effect with iron salts, zinc, sucralfate
Decreased absorption with antacids
Nursing considerations
Arrange for culture and sensitivity tests before beginning therapy.
Continue therapy for 2 days after the signs of infection have disappeared.
Administer oral drug 1 hr before or 2 hr after meals with a glass of water.
Ensure that patient is well hydrated.
Administer antacids at least 2 hr after dosing.
Monitor clinical response; if no improvement is seen or a relapse occurs, repeat culture and sensitivity

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