Scribd
Upload
26 views

Institute of Chemical Technology Syllabus For M. Tech. BPT Entrance Exam 2010-2011

The document outlines the syllabus for the M. Tech. BPT entrance exam at the Institute of Chemical Technology. It covers 3 main sections: [1] chemical engineering science topics like material balances, kinetics, thermodynamics, and unit operations; [2] chemical and biological sciences like organic chemistry, biochemistry, microbiology, and molecular biology; and [3] biotechnology and biochemical engineering topics such as fermentation, downstream processing, biologicals/biopharmaceuticals, and analytical methods. The syllabus provides an overview of the core concepts examined in the entrance test.

Uploaded by

ArinjayKumar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
26 views

Institute of Chemical Technology Syllabus For M. Tech. BPT Entrance Exam 2010-2011

The document outlines the syllabus for the M. Tech. BPT entrance exam at the Institute of Chemical Technology. It covers 3 main sections: [1] chemical engineering science topics like material balances, kinetics, thermodynamics, and unit operations; [2] chemical and biological sciences like organic chemistry, biochemistry, microbiology, and molecular biology; and [3] biotechnology and biochemical engineering topics such as fermentation, downstream processing, biologicals/biopharmaceuticals, and analytical methods. The syllabus provides an overview of the core concepts examined in the entrance test.

Uploaded by

ArinjayKumar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 3

Institute of Chemical Technology

Syllabus for M. Tech. BPT Entrance Exam 2010-2011

1. Section 1: Chemical Engineering science:

Basic Knowledge in the following areas :

Material and Energy Balances : Laws of mass conservation, chemical stoichiometry,


heats of reactions, law of mass action

Numerical methods, Probability and Statistics : Numerical solutions of linear and


non-linear algebraic equations Integration by trapezoidal and Simpsons rule, single and
multi-step methods for differential equations. Definitions of probability and sampling
theorems, Conditional probability, Mean, median, mode and standard deviation, Random
variables, Poisson, Normal and Binomial distributions. Correlation, linear regression and
analysis.

Thermodynamics: Laws of conservation of mass and energy; degree of freedom


analysis. First and Second laws of thermodynamics, reversible and irreversible
processes, internal energy, enthalpy, Kirchoffs equation, heat of reaction, Hess law, heat
of formation, Applications of first law to close and open systems, Second law and
Entropy Thermodynamic properties of pure substances: equation of state and departure
function, free energy, and work function. Gibbs-Helmholtz equation, Clausius-Clapeyron
equation, free energy changeand equilibrium constant, Troutons rule, properties of
mixtures: partial molar properties, excess properties and activity coefficients; phase
equilibria: predicting VLE of systems; Azeotrope and eutectic mixtures, and ideal gas
mixtures, Third law of thermodynamics.

Chemical Reaction Engineering : Basic laws of chemical kinetics, chemical rate


equations, parallel, sequential and other complex system kinetics, differential and
integral kinetics analysis, CSTR and Plug Flow reactors, ideal and non-ideal reactors,
tank-in-series and APDF models, residence time distribution concept, homogeneous
and heterogeneous catalysis

Fluid Mechanics: Fluid statics, Newtonian and non-Newtonian fluids, Bernoulli equation
and its application, energy balance, flow through pipeline systems (laminar and turbulent
flows, friction factor), flow meters, pumps and compressors, packed and fluidized beds,
size reduction and size separation; free and hindered settling; centrifuge and cyclones;
thickening and classification, filtration, mixing and agitation; conveying of solids. Relation
between stress and strain rate for Newtonian fluids.

Heat and Mass Transfer: Conduction, convection and radiation, heat transfer
coefficients, steady and unsteady heat conduction, boiling, condensation and
evaporation; types of heat exchangers and evaporators. Fick's laws, Diffusion of fluids,
mass transfer coefficients, film, penetration and surface renewal theories;
momentum, heat and mass transfer analogies; stagewise and continuous contacting and
stage efficiencies; HTU & NTU concepts design and operation of equipment for
distillation, absorption, leaching, liquid-liquid extraction, drying, humidification,
dehumidification and adsorption.

Unit Operations: Principles of design of Unit Operations like Distillation, Absorption,


Drying, Crystallization, Evaporation, L-L Extraction etc.

2. Section 2: Chemical and Biological Sciences

Basic ideas in the following areas:

Chemistry and chemical equilibria: Ionic and covalent bonding, M.O. and V.B.
approaches for diatomic molecules, VSEPR theory and shape of molecules,
hybridisation, resonance, dipole moment, structure parameters such as bond length,
bond angle and bond energy, hydrogen bonding, van der Waals interactions. Ionic
solids, ionic radii, lattice energy (Born-Haber Cycle). Identification of functional groups by
chemical tests. Acids and bases, electronic and steric effects, optical and geometrical
isomerism, tautomerism, conformers, concept of aromaticity. Reaction kinetics: Rate
constant, order of reaction, molecularity, activation energy, zero, first and second order
kinetics, catalysis and elementary enzyme reactions. Colligative properties of solutions,
ionic equilibria in solution, solubility product, common ion effect, hydrolysis of salts, pH,
buffer and their applications in chemical analysis, equilibrium constants for
homogeneous reactions. Zeta potential and electronic double layer.

Biochemistry: Biochemical role of hormones, vitamins, proteins, enzymes, coenzymes,,


nucleic acids and bioenergetics. Metabolism of lipids, proteins and carbohydrates,
Principles of immunology. Protein structure, folding and function: Lysozyme,
Ribonuclease A, Carboxypeptidase and Chymotrypsin. Enzyme kinetics including its
regulation and inhibition. Glycolysis, TCA cycle, pentose phosphate pathway, oxidative
phosphorylation, gluconeogenesis and glycogen metabolism. Photosynthesis: the Calvin
cycle. Methods and applications of immobilization of cells and enzymes; kinetics of
soluble and immobilized enzymes; biosensors.

Microbiology: Microbial Taxonomy and Diversity: Bacteria, Archea and their broad
classification; Eukaryotic microbes: Yeasts, molds and protozoa; Viruses and their
classification; Molecular approaches to microbial taxonomy. Prokaryotic and Eukaryotic
Cells: Structure and Function: Prokaryotic Cells: cell walls, cell membranes,
mechanisms of solute transport across membranes, Flagella and Pili, C. Pure culture
techniques; Eukaryotic cell organelles: Endoplasmic reticulum, Golgi apparatus,
mitochondria and chloroplasts. Microbial Growth: Definition of growth; Growth curve.

Molecular Biology: PCR and RT-PCR, microarray technology, DNA fingerprinting and
recombinant DNA technology; prokaryotic and eukaryotic expression systems; Vectors:
plasmids, phages and cosmids. Gene mutation: Types of mutation; UV and chemical
mutagens; Selection of mutants; Ames test for mutagenesis; Bacterial genetic system:
transformation, conjugation, transduction, recombination, transposons; DNA repair and
chromosomal aberrations.

3. Section 3: Biotechnology and Biochemical Engineering:

Fermentation and Tissue culture (plant and mammalian): Microbial growth kinetics;
batch, fed-batch and continuous culture of microbial cells; media for industrial
fermentations; sterilization of air and media, design and operation of stirred tank, airlift,
plug flow, packed bed, fluidized bed, membrane and hollow fibre reactors; aeration and
agitation in aerobic fermentations; bioprocess calculations based on material and energy
balance. Nutritional requirements for animal cell culture; techniques for mass culture of
animal cell lines; application of plant and animal cell culture. Applications of cell
culture technology for production of vaccines, growth hormones; interferons, cytokines
and therapeutic proteins; hybridoma technology and gene knockout; stem cells and its
application in organ synthesis; gene therapy; transgenic animals and molecular
pharming.

Bioreactor design and control: Types of bioreactors and their operation, various
control systems, photobioreactors, bioreactors for microbial and mammalian cell
systems.

Downstream processing in industrial biotechnology: Extraction: solid-liquid and


liquid-liquid, supercritical fluid extraction, extractors; precipitation, centrifugation, cell
disintegration. Chromatographic purification: principle, ion exchange, reverse phase,
affinity and gel filtration; Drying: principle, spray and freeze drying, Filtration: principle,
types, filer aids, microfiltration, ultrafiltration and nanofiltration, plate and frame filter,
sparkler filter. Sedimentation: principle, stocks low and applications.

Biologicals and Biopharmaceuticals: Antibodies: polyclonal and monoclonal


antibodies, catalytic antibodies, diagnostic antibodies; production of antibodies,
vaccines: types, production and applications; Therapeutic proteins and peptides: Insulin,
erythropoietin, interleukins, hormones, sterilization methods for biopharmaceuticals.

Bioanalyticals and related analytical methods: Absorption spectroscopy (UV, Visible


and IR), fluorimetry, conductometry, potentiometery, principles of mass, NMR and ESR
spectroscopy, X-ray diffraction and analytical chromatographic methods, hyphenated
techniques in bioanalysis, Pharmacopoeial assay, LAL-Test, BET Test, Principles and
methods of microbial assay of pharmacopoeia, filter integrity test, sterility testing of
biopharmaceuticals, methods of analysis of for proteins. Electrophoresis (PAGE, SDS-
PAGE); Immunological techniques: Immunodiffusion, immunoelectrophoresis, RIA and
ELISA.

Applications of Biotechnology in Food and Pharmaceutical Technology areas :


Use of biologicals and biotechnological processes to make food and pharma products
including microbial and enzymatic biotransformations; Biological sciences involved in
action of bioactives in health care in food and pharma products.

You might also like