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Piperazine Hexahydrate Data Sheet

Piperazine hydrate is a white, deliquescent crystalline compound used as an anthelminthic. It is composed of piperazine salt and water. According to the product data sheet, it melts between 159-196°C, is freely soluble in water and alcohol, and contains no more than specified levels of impurities such as ethylene diamine or heavy metals. Piperazine hydrate is commonly used to treat intestinal worm infections in children.

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80 views

Piperazine Hexahydrate Data Sheet

Piperazine hydrate is a white, deliquescent crystalline compound used as an anthelminthic. It is composed of piperazine salt and water. According to the product data sheet, it melts between 159-196°C, is freely soluble in water and alcohol, and contains no more than specified levels of impurities such as ethylene diamine or heavy metals. Piperazine hydrate is commonly used to treat intestinal worm infections in children.

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Anonymous T32l1R
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© © All Rights Reserved
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G.

AMPHRAY LABORATORIES
Piperazine Hydrate BP/EP/IP Product Data Sheet
CAS No. 142-63-2
C4H10N2,6H2O Molecular Weight : 194.2
INFORMATION OF THE PRODUCT
Sr.No. Information
1 Name of the Product : Piperazine Hydrate BP/EP/IP
2 Structure :

3 Composition : It is composition of Piperazine salt and water


4 Chemical Name (IUPAC) : Piperazine Hydrate
5 Properties : Anthelminthic
6 Specification Appearance (As per Ph. Eur./IP) A colourless, deliquescent crystals.
It melts at about 43 c.
Solubility (As per Ph. Eur./IP) Freely soluble in water and alcohol.
Identification
A) IR As per Ph. Eur./IP) IR spectrum of sample is concordant with that of
the reference standard
B) TLC (As per Ph. Eur./IP) The Rf value of the principal spot obtained from
the test solution correspond to that obtained
from the standard solution
C) Melting point (As per Ph. Eur.) The melting range is Between 191 C to 196 C
D) Melting point (As per IP) It melts at about 159 C
Appearance of solution (As per Ph. The solution is clear and colourless
Eur. / IP)
Related Substances (As per Ph. Eur. Ethylene diamine : NMT- 0.25 %.
/IP) Triethylene diamine : NMT- 0.25 %.
Heavy Metal (As per Ph. Eur. /IP) NMT 20 ppm
Sulfated Ash (As per Ph. Eur. /IP ) NMT 0.1 %

pH (As per IP) 10.5 to 12.0


Assay
Assay by titration (As per Ph.Eur./ 98.0 % to 101.0%
IP)
Additional tests (In-house )
Particle size ~ 100 % passing through 16 mesh / 30 mesh
G. AMPHRAY LABORATORIES

Sr.No. Information
7 Uses : It is used as a partial intestinal obstruction by the common roundworms, a condition
primarily occurring in children.
Ref .Wikipedia
8 Packing : 25 Kg. or 40 Kg. or 50 Kg. Fibre Drums with inner liner
25 Kg. or 50 Kg. Plastic Drums with inner liner

9 Shelf life : Expiry Date: Five years from Date of manufacturing.

10 Storage : Store in closed container in cool, dry place & protect from light, heat dust & other
contaminants.

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