This document describes several movement disorders including their presentation and characteristic lesions or notes. Akathisia causes restlessness and an urge to move and can be seen with neuroleptic use or Parkinson's disease. Asterixis presents as a flapping motion of the wrists and is associated with hepatic encephalopathy, Wilson's disease or other metabolic derangements. Athetosis involves slow, snake-like writhing movements especially of the fingers and has a characteristic basal ganglia lesion. Chorea features sudden jerky movements and also has a characteristic basal ganglia lesion, such as seen in Sydenham's chorea of rheumatic fever.
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Movement Disorders PDF
This document describes several movement disorders including their presentation and characteristic lesions or notes. Akathisia causes restlessness and an urge to move and can be seen with neuroleptic use or Parkinson's disease. Asterixis presents as a flapping motion of the wrists and is associated with hepatic encephalopathy, Wilson's disease or other metabolic derangements. Athetosis involves slow, snake-like writhing movements especially of the fingers and has a characteristic basal ganglia lesion. Chorea features sudden jerky movements and also has a characteristic basal ganglia lesion, such as seen in Sydenham's chorea of rheumatic fever.
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DISORDER: Akathisia
PRESENTATION: Restlessness and intense urge to move
NOTES: Can be seen with neuroleptic use or in Parkinson disease. ------------------------------------------------------------------------- DISORDER: Asterixis PRESENTATION: Extension of wrists causes “flapping” motion NOTES: Associated with hepatic encephalopathy, Wilson disease, and other metabolic derangements. --------------------------------------------------------------------------------- DISORDER: Athetosis PRESENTATION: Slow, snake-like, writhing movements; especially seen in the fingers CHARACTERISTIC LESION: Basal ganglia ----------------------------------------------------------------------------------- DISORDER: Chorea PRESENTATION: Sudden, jerky, purposeless movements CHARACTERISTIC LESION: Basal ganglia NOTES: Chorea = dancing. Sydenham chorea seen in acute rheumatic fever. -------------------------------------------------------------------------------- DISORDER: Dystonia PRESENTATION: Sustained, involuntary muscle contractions NOTES: Writer’s cramp, blepharospasm, torticollis. ------------------------------------------------------------------------------ DISORDER: Essential tremor PRESENTATION: High-frequency tremor with sustained posture (eg, outstretched arms), worsened with movement or when anxious. NOTES: Often familial. Patients often self- medicate with alcohol, which decreases tremor amplitude. Treatment: nonselective β-blockers (eg, propranolol), primidone. DISORDER: Hemiballismus PRESENTATION: Sudden, wild flailing of 1 arm +/− ipsilateral leg CHARACTERISTIC LESION: Contralateral Subthalamic nucleus (eg, lacunar stroke). NOTES: Pronounce “Half-of-body ballistic.” Contralateral lesion. --------------------------------------------------------------------------------- DISORDER: Intention tremor PRESENTATION: Slow, zigzag motion when pointing/extending toward a target. CHARACTERISTIC LESION: Cerebellar dysfunction _________________________________________________________ DISORDER: Myoclonus PRESENTATION: Sudden, brief, uncontrolled muscle contraction NOTES: Jerks; hiccups; common in metabolic abnormalities such as renal and liver failure. ------------------------------------------------------------------------------------------------ DISORDER: Resting tremor PRESENTATION: Uncontrolled movement of distal appendages (most noticeable in hands); tremor alleviated by intentional movement CHARACTERISTIC LESION: Substantia nigra (Parkinson disease). NOTES: Occurs at rest; “pill-rolling tremor” of Parkinson disease. When you park your car, it is at rest.