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Mouthwash Carrier / Vehicle: Alcohol 10-20% - Solubilizer For VO

This document summarizes the composition and properties of various oral and skin care products: 1) Mouthwashes typically contain water, alcohol (10-20%) as a solubilizer and preservative, and a humectant like glycerin (5-20%). They are used to decrease bacteria in the mouth and treat oral diseases. 2) Astringent skin lotions contain ingredients like lactic acid or alum to toughen and shrink tissues and reduce pore size. Lactic acid is a colorless syrup that is miscible with water and alcohol but also corrosive. 3) Toothpastes are abrasive pastes or powders used to introduce active ingredients

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Khryzha Lacsamana
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40 views3 pages

Mouthwash Carrier / Vehicle: Alcohol 10-20% - Solubilizer For VO

This document summarizes the composition and properties of various oral and skin care products: 1) Mouthwashes typically contain water, alcohol (10-20%) as a solubilizer and preservative, and a humectant like glycerin (5-20%). They are used to decrease bacteria in the mouth and treat oral diseases. 2) Astringent skin lotions contain ingredients like lactic acid or alum to toughen and shrink tissues and reduce pore size. Lactic acid is a colorless syrup that is miscible with water and alcohol but also corrosive. 3) Toothpastes are abrasive pastes or powders used to introduce active ingredients

Uploaded by

Khryzha Lacsamana
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Manufacturing Laboratory

Notes

MOUTHWASH
- An aqueous solution which is most Carrier / vehicle
often used for its deodorant, Alcohol 10-20% - solubilizer for VO
refreshing and antiseptic properties - preservative
- Pleasant rinser - enhances flavor
- Cleansing mouth / treating diseases - aid in unmasking unpleasant taste
of oral mucus membrane water – principal diluent
- Decreases bacterial concentration
and odor in mouth for a short period Humectant
of time Glycerin – 5- 20%
*bacterial growth is caused by residues Sorbitol
from food - more viscous
- certain body mouthful effects
Therapeutic - Enhances sweetness
- Reduces plaque, dental carries, *w/ ethanol – increases preservative
gingivitis and stomatitis. quality of the product
Cosmetic
- Prevents bad breath and has anti- Surfactant
infective and flavoring agents. - 0.1 – 0.5%
- Solubilizes flavor
2 properties to consider: - Foaming action
- Assists removal of oral debris
Taste - Decreases surface tension
- most important for consumer
acceptability Cationic – most toxic; cetylpyridium
Clarity chloride
- clear solution Anionic – sodium lauryl sulfate
Non-ionic – least toxic; polyoxyethylene,
Antibacterial polyoxypropylene
Ex: alcohol, chlorhexidine,
gluconate, cetyl pyridium, hexetidine, Flavorant
chloride, benzoic acid, methyl salicylate, - Overcome unpleasant taste
benzalkonium chloride, fluoride hydrogen Ex: Peppermint, spearmint, cinnamon,
peroxide wintergreen oils, menthol
Essential oils: eucalyptus oil, thymol,
Antiseptic / anti-infective properties clove oil
Hexetidine – Bactidine
Benzoic acid – Listerine

Lacsamana, K
Sweetener
Saccharin Glycerin – emollient
- Fermentable sugars should be Alcohol – cosolvent
avoided Water – diluent

Astringent
- Precipitates proteins
- Coagulates loose mucus secretions
Ex: Zinc chloride, alum, tannic acid, citric
acid

Others:
Special deodorant:
- Masking unpleasant odor
Halitosis – bad breath
Morning breath – product of sleep

Direction:
Dilute one capful in enough water and rinse
for 30 seconds. Do not swallow.
For external use.

ASTRINGENT SKIN LOTION


Skin – largest organ
- 6% body weight
- pH 5-6
- used to toughen and shrink tissues,
reduces pore size
- used to decrease skin blanching
- irritant/caustic effect

Lactic acid
2-hydroxypropionic acid; Milk acid
- colorless or yellowish syrup
- miscible with water and alcohol
- corrosive
*10% sol’n antiseptic for neonates; anti
diaper rash

Alum
1:7 water, 0.5-5%

Lacsamana, K
TOOTHPASTE
- considered as a dentrifice
- substances that are abrasive to
remove stain pellicles
- vehicle to introduce active
ingredient into the oral cavity
- paste, powder or liquid
paste: most important
- inherent consumer benefits, not
abrasive

COMPOSITION

Abrasive:
- mechanical cleansing effect
- helps remove stained pellicle
*pellicle – protein film that forms on the
surface of enamel by selective binding of
glycoproteins coming from saliva that
prevents continuous deposition of salivary

Lacsamana, K

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