NO.

APA CITATION FOCUS OF THE SCOPE OF THE METHOD USED RESULTS OF THE MAIN CONCLUSION MAIN
PAPER PAPER STUDY RECOMMENDA
TION

1 Elixabet Díaz-de- The study focuses on The scope of the The methods used are The results of the The researchers It is
Cerio, Vito Verardo, the health effects of paper are the through compiling data of study are the further conclude that the recommended
Ana María Gómez- Guava Leaves. reviewed the different vitro and vivo applications found traditional claims that this study
Caravaca, Alberto journals, studies carried out with with guava leaves: generally require will help the
Fernández- websites, books, guava leaves over the firstly, to prepare experimental future
Gutiérrez, and and several last decade. gelatin beads with research to establish researchers to
Antonio Segura- databases as marine-fish gelatin for their effectiveness. In know the various
Carretero (2017) “Scopus”, various applications this regard, effects of taking
“Google Scholar”, such as medicine, ethnomedicine guava leaves in
Health Effects of “PubMed”, and and the food and applications of our life. The
Psidium guajava L. “ScienceDirect”, pharmaceutical Psidium guajava L. study is reliable
Leaves: An were used to industries. Secondly, leaves have been because it
Overview of the Last compile them. To Giri et al. suggested verified by several contains exactly
Decade ensure that guava leaves as researches over the gathered
relevant works supplementary feed last decade against information with
Retrieve from: are included, for the fish species many disorders, evidences.
https://www.ncbi.nlm terms such as Labeo rohita, due to demonstrating its
.nih.gov/pmc/articles “Psidium the immune- potential in the
/PMC5412476/ guajava”, stimulatory effect. treatment of the most
 “guava”, “leaves”, The same conclusion common worldwide
“in vitro”, “in vivo”, was reached by diseases. In addition,
“clinical”, “trial”, Fawole et al. in L. the effects of the
“food application”, rohita. Thirdly, Gobi leaves have been
and those related et al. reported that related to individual
with the diseases guava leaf powder, compounds such as
such as mixed with a quercetin, catechin,
“bacteria”, commercial diet, vescalagin, gallic
“cancer”, “blood”, strengthened the acid, peltatoside,
“glycaemia”, and immunological hyperoside,
“oral”, among response of isoquercitrin, and
others were Oreochromis guaijaverin.
matched in the mossambicus, and
search. Only recommended the
complete leaves as feed
available works complement in
published in aquaculture.
English, Spanish,
and Portuguese
have been
included.

2 A Systemic Review The study focuses in The scope of the The method used is a The results of the The conclusion of the It is
on Antioxidant and reviewing the study is the computerized literature study is that out of a study is that the recommended to
Hepatoprotective antioxidant and searched articles, search was conducted total of 152 articles antioxidant activity of conduct an
 Effect of hepatoprotective studies and using PubMed, Medline on guava resulted 19 Psidium guajava may experimentation
Psidium Guajava activity of psidium literatures that and Google search studies which were be due to inhibition of to know its
Leaf and Fruit guajava. are needed in engine using different key related to antioxidant the formation of effectiveness.
Extract investigation and words for studies and hepatoprotective radicals,
analyzation. investigating. activity of leaf and scavenging of the
Tesfahun Molla, The reference lists of the fruit extract were formed free radicals,
Habtamu retrieved articles helped included in this reducing of oxidized
Azene(2017) me to find further articles, review. These were intermediates and the
relevant to the present then categorized into presence of the
Retrieve from: review that was not six groups; 1) Six phenolic compounds.
https://pdfs.semantic revealed through the studies on in vitro It also acts as
scholar.org/62c2/c6 searching procedure. antioxidant studies promising
0fc13aab33281375c with leaf extracts, 2) hepatoprotective
62b6d43f25cb102d7 four studies on in which is correlated
.pdf vitro antioxidant directly with its ability
studies with fruit to reduce activity of
extract, 3) one in vivo serum enzymes and
study on antioxidant enhance antioxidant
with leaf extract defense status. The
in rat, 4) one in vivo phenolic content in
study on antioxidant Psidium guajava
with fruit extract in extract played a
rat, 5) one study significant role on the
antioxidant fruit antioxidant and
extract in human hepatoprotective
and 6) six in vivo activity.
 studies on
hepatoprotective with
leaf extract in rat.

3 Iim Sukarti, Noer The study focuses on The scope of the The method is The results of the They conclude that It is
Laily, Retno Windya the purpose of Guava paper is the experimental research study were the the guava leaf has recommended to
Kusumaningtyas, (Psidium guajava L.) various design because they outcome of different great potential to be have more
Maria Rosari Devi leaf extract as a components that extract various extraction times and developed as studies about
Kartika Rini (2015) functional ingredient they use in order components. solvents used on functional ingredients. this kind of
for immunostimulant. to come up to optimization of Firstly, they are study.
The Potency of their results and extraction. In water widely available, with
Guava Psidium possible solvent, the highest a guaranteed supply.
Guajava (L.) Leaves outcome. These phenol total content Secondly, guava leaf
as a Functional are the extraction occurred in the naturally occurring
Immunostimulatory of water, ethanol, extraction time 20 compounds, and their
Ingredient reagents, and min. While extraction extraction is relatively
calibration curve used ethanol solvent, cost effective. Lastly,
Retrieve from: of gallic acid, the highest phenol they contained high
https://www.researc measurement of total content was level of antioxidant,
hgate.net/publication DPPH, and achieved at phenolic compound
/273790177_The_P lymphocyte extraction time 6 h. In and biological
otency_of_Guava_P isolation. both conditions, the activities as
sidium_Guajava_L_ phenol total content immunostimulatory
Leaves_as_a_Functi of water and ethanol agents. Based on the
onal_Immunostimula extract were not measurements
 tory_Ingredient significantly different, results of phenol total
101.93 and 101.20, content, antioxidant
respectively. and immunostimulant
However, parameters activity, the active
measured in this compounds of the
study could not guava leaf expected
explain why the to have
polyphenolic immunostimulatory
compounds in the activity were probably
water and ethanol not only polyphenolic
extracts were similar.

4 J. V. Kamath, Nair The study focuses on The scope of the The method used is by The results of the The conclusion of the It is
Rahul, C. K. Ashok the review of the study is the collecting research study In a study study is that the plant recommended to
Kumar, S. Mohana guava leaves. articles that are articles that are related to carried out with leaf has been extensively use
Lakshmi (2014) needed in the the power of curing of extract of the plant, studied in terms of experimentation
review specially guava leaves. inhibition of pharmacological design in order
Psidium guajava L: its gastrointestinal activity of its major to improve the
A review - phytochemistry release of components, and the study review.
International Journal and biolofical acetylcholine by results indicate potent
of Green Pharmacy activity. quercetin present in anti-diarrheal,
extract was antihypertensive,
Retrieve from: suggested as a hepatoprotective,
https://greenpharma possible mode of antioxidant,
cy.info/index.php/ijg action in the antimicrobial,
 p/article/view/386/40 treatment of acute hypoglycemic
7 diarrheal disease. and antimutagenic
Guava fruit and leaf activities. In recent
showed antioxidant years, emphasis
and free radical of research has been
scavenging capacity on utilizing traditional
Guava leaf extract medicines
showed anti-cough that have a long and
activity by reducing proven history of
the frequency of treating various
cough ailments. In this
induced by capsaicin regard, further
aerosol. studies need to be
carried
out to explore P.
guajava L for its
potential in
preventing
and treating
diseases.

5 Arun K. The study focuses on The scope of the The method used is The results of the The conclusion of the An increase in
Gandu, Vikram the ointment made by study is the experimental research study is with P. study that P. guajava concentration of
Goud Gollapally, the extract guava people who has design to make the guajava leaf extract is leaf extract had a the leaf extract
Vinayak Kandikattla, leaves that can heal wounds so that it product properly and active with regards to slow wound healing was
Thejaswi Thigulla, wounds. can check its accurately. wound healing but capacity in recommended
 Praveen kumar effectiveness. may require a longer comparison to for the future
Yajjala (2017) duration that the Fucidin and researchers.
Fucidin and Topiderm Topiderm. An
Wound healing of the control group. increase in
effect of Psidium concentration of the
guajava (Guava leaf extract was
Leaf) extract recommended for the
ointment in future researchers.
comparison to
Fucidin® and
Topiderm® on
incisional wounds in
ICR mice.

Retrieve from:
http://www.herdin.ph
/index.php/journals?
view=research&cid=
63362

6 Muthukumaran The study focuses on The scope of the The study has three The result of the The conclusion of the It is
Jayachandran, the regulation of NF-kB study are the methods namely study is that the study that GLE has recommended to
Ramachandran by GLE evidences that phytocompounds Experimental Animals Diabetes Mellitus the great ability to cut use this study by
Vinayagam, Ranga inflammation that are analyzed: and Conditions which (DM) is a back plasma glucose the future
Rao Ambati , plays a major role 3,4- means experiments were combination of and oxidative stress researchers
 Baojun Xu , and within the DM. Dihydroxybenzald executed in accordance heterogeneous and conjointly because of its
Stephen Sum Man ehyde and its with the principles issued disarray commonly ameliorates the validity and to
Chung (2018) PubChem CID is by the presenting with the burden of develop the
70949. National Institute of incidence of inflammation in STZ study.
Guava Leaf Extract Chlorogenic acid Health (NIH) Guideline hyperglycemia and evoked diabetic rats
Diminishes and its PubChem for the experimental glucose intolerance, as confirmation by
Hyperglycemia and CID is 1794427. animals care and use, as a result of lack of reduced glucose
Oxidative Stress, Protocatechuic Induction of Experimental insulin, defective and restored
Prevents Cell Death, acid and its Diabetes in Animals and insulin action, or antioxidant levels,
Inhibits PubChem CID is Experimental Design of both.There is enough besides reduced
Inflammation, 72. Animal Study. proof to demonstrate expression
and Regulates NF- Gallic acid and its that hyperglycemia of inflammatory
kB Signaling PubChem CID is plays an important proteins. Te benefcial
Pathway in STZ 370. role in initiating efects of GLE on
Induced Vanillic acid and oxidative stress and oxidative stress and
Diabetic Rats its PubChem CID diferent complications infammation in
is 8468. associated with DM. diabetic rats were
Retrieve from: Cafeic acid and In the current study, well
http://downloads.hin its PubChem CID we have examined visualized in our
dawi.com/journals/b is 689043. the role of bioactive histological studies.
mri/2018/4601649.p Vanillin and its compounds in GLE Te mechanism of
df PubChem CID is such as phenolic action of GLE may be
1183. compounds on owing to its ability to
p-Coumaric acid antidiabetic activity in suppress the
and its PubChem STZ evoked diabetic hyperglycemia by
CID is 637542. rat model system. regulating the
 Syringaldehyde There are several secretion of insulin
and its PubChem reasons for choosing from the pancreatic
CID is 8655. GLE; beta-cells and in
Ferulic acid and the important aspect turns it may
its PubChem CID we considered is that ameliorate
is 445858. it has no side the oxidative stress
Sinapic acid and effects and no toxicity and confirm the
its PubChem CID even at higher doses. availability of enough
is 637775. antioxidant enzymes
Salicylic acid and and it is well known
its PubChem CID that presence
is 338. of oxidative stress
and infammation will
initiate NF-kB
activation; thus GLE
alleviated the
symptoms of diabetes
by
a successive
regulation of
hyperglycemia
followed by oxidative
stress and NF-kB
pathway regulation.

7 Krishna Prasad The study focuses on The scope of the The method of the study The result of the The conclusion of the It is
 Mahato, Rakibul the in determining the study are the is experimental research study is that there study is that guava recommended
Islam, Md. growth, antibacterial needed bacteria, design wherein the was significantly leaf (Psidiumguajava) that further
Mahmudul Hasan, and hematological which is E. Coli researchers test the E. increased in body suspension research is
Md. Gausur effects of guava leaf and the extraction Coli weight in T2 (guava effectively controlled needed to
Rahman (2016) (Psidiumguajava) of guava leaves. leaf extract) and T3 E. coli infection and ascertain the
suspension in E. coli group (Doxycycline) had mechanism of
Efficacy of Guava infected Japanese than T0 (negative effective antibacterial action for its
Leaves quail under the control) and T1 activity. Guava leaf application in
(Psidiumguajava) Department of (positive control). At and Doxycycline clinical practice.
Suspension on Physiology and the age of 32 days had the similar effect
Growth, Pharmacology, HSTU, the highest body on the body weight
Antibacterial and Dinajpur, Bangladesh. weight was found in and bacterial load.
Hematological T3 group
Performances in E. (98.30±1.66) followed
coli Included by T2 (96.50±1.95),
Japanese Quail T0 (89.20±1.34) and
T1 (80.80±3.70).The
Retrieve from: present results are
https://pdfs.semantic more or less similar
scholar.org/211b/b2 to the study of
21a62aa063f948ff17 Geidam et al., (2015),
5ea8219883f96485. who reported that
pdf body weight was
found higher in guava
extract and
oxytetracycline than
 group infected with E.
col

8 D Ishartani, The study focuses in The scope of the The method used is The results of the The conclusion of the Red guava fruits
Rahman, R determining the effect study is the Completely Randomized study is that it study is that 6 days ripened for 6
Hartanto, R Utami of red guava fruit things needed in Design with fruit ripening showed that fruit ripening time gives days were
and L U Khasanah ripening time on the conducting the time (without ripening, 4 ripening time better chemical, recommended
(2018) physical (overrun and experimentation days, and 6 days) as significantly affected physical and sensory as raw material
melting rate), chemical especially the red single factor. The the physical, characteristics of the in velva making.
Physical, chemical (vitamin C, pH, total guava. research chemical and sensory velva compare to 4
and sensory dissolved solid) and was conducted in characteristic of the days ripening time.
characteristics of red sensory (color, taste, triplicate. Chemical and velva. Vitamin C, pH, Red guava fruits
guava aroma, texture, and physical characteristic and total solid of the ripened for 6 days
(Psidium guajava) overall compare to data was analyzed using velva were increased were recommended
velva at different control (without One Way Analysis of as the ripening time as raw material in
fruit ripening time ripening) velva) Varian whether sensory prolonged. In other velva making.
characteristic of red characteristic data was hand, increasing of
Retrieve from: guava velva. analyzed using fruit ripening time
https://iopscience.io Independent Sample T- decreased the
p.org/article/10.1088 test. overrun and melting
/1755- rate of the velva. Red
1315/102/1/012075/ guava velva made
pdf from 6 days
ripening had better
sensory
characteristics
 compared to velva
made from red guava
fruit without ripening
or 4 day ripening.

9 Sumra Naseer The study focuses on The scope of the The method used is by The results of the The conclusion of the It is
Shabbir Hussain the phytochemistry study is using the historical study is that it is study is that guava recommended to
Naureen Naeem and medical value of Antimicrobial background of guava. found to be effective possesses anti-viral, use experimental
Muhammad Pervaiz guava leaves. activity, in diarrhea, anti-inflammatory, tests in order to
Madiha Rahman Antidiarrheal dysentery, anti-plaque, analyze and
(2018) activity Anti- gastroenteritis, antinociceptive interpret
inflammatory hypertension, activity and anti- accurately its
The phytochemistry activity and diabetes, mutagenic activities. effectiveness.
and medicinal value Antioxidant caries, pain relief, Due to these
of Psidium guajava activity. cough, oral ulcers biological activities it
(guava) and to improve is can be quite helpful
locomotors for the preventions
Retrieve from: coordination and liver and treatments of
https://link.springer.c damage diseases. Ethanolic
om/article/10.1186/s inflammation. extract of guava can
40816-018-0093-8 Its skin contains a lot increase the sperm
of phytochemicals in quality and quantity
intuits fruit and can be used for
which is rich in the treatment of
vitamins (A & C), infertile males.
 iron, phosphorus and
calcium and minerals.
The phenolic
compounds in
guava help to cure
cancerous cells and
prevent skin
aging before time.

10 Divyashree Saikia The study focuses on The scope of the An investigation was The results of the The conclusion of the It is
and Utpal Kotoky the efficacy of study is the fresh conducted to study the study is that It has study is that, 60 recommended to
(2019) chemicals on the fruit to find the efficacy of chemicals on been found from the ppm NAD proved to the future
quality parameters of TSS of it and the the quality parameters of present experiment be the best chemical researchers to
Study the Efficacy of Guava. acidity and sugar. guava in the that, 60 ppm NAD Treatment for test in more
Chemicals on the Experimental Farm and treatment significantly enhancing the quality labarotory.
Quality Parameters Laboratory, Department helped in DE and production of
of of Horticulture, College of blossoming of flowers highly remunerative
Guava (Psidium Agriculture, Assam in the rainy crop.
guajava L) cv. Agricultural University, season and
Lucknow – 49 Jorhat during 2016- increased the yield
2018. along with TSS
Retrieve from: content, reducing
https://www.ijcmas.c sugar, non-reducing
om/8-1- sugar,
2019/Divyashree%2 total sugar, ascorbic
0Saikia%20and%20 acid and decrease in
Utpal%20Kotoky.pdf triable acidity in the
winter season