Blood Transfusion Error Prevention - Nurses Role
Blood Transfusion Error Prevention - Nurses Role
In spite of such strict clinical measures on blood transfusion, there are certain areas in
transfusion process which requires acute attention. For example, the fatal acute
hemolytic reactions to transfusion caused by ABO incompatibility have been attributed
to administrative errors. The mismatch of blood units with that of the patient blood as a
result of negligence is a serious cause of patient fatality. Apart from ABO incompatibility,
contamination of red cells especially of bacterial origin is a matter of concern. Yersinia
enterocolitica is a common organism found to cause contamination of red cells (Carson
et.al, 1999). The infection of such organisms seems to be related to the storage period
of blood units. Contamination of platelets is another serious cause where
Staphylococcal infection is very common. Klebsiella and Serratia have also been
detected in platelet contamination. Transfusion related acute lung injury is an acute
respiratory distress occurring within hours after transmission, usually characterized by
hypoxia due to pulmonary edema.
The blood transfusion errors that often occur due to negligence of nurses include the
following:
1. Samples being mislabelled with another patient’s identity.
2. Blood being ordered for wrong patient.
3. Other blood components being ordered for wrong patient.
4. Blood sample being taken from wrong patient.
5. Patient given Rh D+ stock from the trauma refrigerator when Rh D- available.
6. Patient being transfused with un-irradiated blood.
7. Albumin being transfused to wrong patient.
8. Autologous blood being discarded because of nurse’s failure to monitor patient
for 4 hours and IV set not infusing.
9. RN returning blood to OR refrigerator after being kept in the theatre for 12+
hours.
10. RN leaving a unit of group B Rh D+ blood in trauma refrigerator for 12+
hours.
11. Unit of RBCs missing from the OR refrigerator with no record of transfusion of
the unit (Callum et.al, 2001).
A lack of awareness of good transfusion practice has been identified as a reason for
poor compliance (Parris, 2007). A bar code patient identification system involving a
hand-held
computer for sample collection and for compatibility testing has been successfully
evaluated recently (Turner et.al, 2003) to help nurses during blood transfusion. A
decentralized phlebotomy skills Programme (Needham, 2001) and cross training in
patient care skills on the nursing units has been found to be effective with reduction in
errors of collection and labelling. Studies have proved that the effective and safe
transfusion of blood depends on a series of linked processes and the safety measures a
nurse should follow for blood transfusion includes donor selection and exclusion, post
collection processing such as leuco-depletion and viral inactivation and neo
technological innovations like the bar-code on the wrist band of each patient (Regan
et.al, 2002).
Recent guidelines for blood transfusion direct that blood should not be transfused
prophylactically and the threshold of transfusion is a hemoglobin level of 7.00 to 8.00
gm per deciliter. The safety directions include selection of donors; heat treatment;
solvent and detergent treatment; methylene blue addition; leucodepletion; irradiation;
minimizing donor exposure and the use of American plasma and Recombinant
products(Goodnough et.al, 1999).Though viral inactivation of cellular products is not
possible with heat, pooled plasma products can be pasteurized at 80° c for 72 hours.
Solvent treatment can be applied to pooled plasma of up to 1000 donations. Methylene
blue and ultraviolet B radiation can inactivate viral products and thus addition of
methylene blue to single units of plasma followed by subsequent irradiation gives the
advantage of not pooling the plasma. Modern leucocyte filters reduce the leucocyte
count to less than 1x106. Leucodepletion seems to reduce nvCJD risks too
(Shaughnessy, 2000).
Conclusions
Published literature throws light on the consequences of blood transfusion errors and
the element of human error involved in such wrong transfusions including administration
to wrong recipient, phlebotomy errors, testing of wrong specimen and failure to detect at
the bedside before transfusion of the wrong unit. A nurse, by profession has
opportunities to establish policies and procedures, design nursing practices, and
educate staff to help avoid blood transfusion errors (Bryan, 2002). There is an urgent
need of training programs in nursing units that educate nurses on blood transfusion risk
reduction, latest safety guidelines, nurse interventions and decision making. There is
also a need for the nurses to be aware the recent advances and technological
innovations in planning and management of transfusion medicine (Nagarajan et.al,
2002). Evidence based clinical guidelines for individual blood components, transfusion
monitoring systems and quality assurance programs are vital to prevent blood
transfusion errors.