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Positive Troponin Test: Lipid Profile

The document discusses troponin tests, which measure cardiac-specific troponin levels in the blood to detect heart injury. There are three types of troponin proteins that regulate muscle contraction. Troponin levels become elevated within 3-4 hours of a heart attack and remain so for 10-14 days, making troponin tests useful for diagnosing heart attacks. New high-sensitivity troponin tests can detect heart injury earlier.
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0% found this document useful (0 votes)
38 views

Positive Troponin Test: Lipid Profile

The document discusses troponin tests, which measure cardiac-specific troponin levels in the blood to detect heart injury. There are three types of troponin proteins that regulate muscle contraction. Troponin levels become elevated within 3-4 hours of a heart attack and remain so for 10-14 days, making troponin tests useful for diagnosing heart attacks. New high-sensitivity troponin tests can detect heart injury earlier.
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© © All Rights Reserved
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Positive troponin test

Troponins are a group of proteins found in skeletal and heart (cardiac) muscle fibers
that regulate muscular contraction. Troponin tests measure the level of cardiac-specific
troponin in the blood to help detect heart injury.

There are three types of troponin proteins: troponin C, troponin T, and troponin I.
Troponin C initiates contraction by binding calcium and moves troponin I so that the two
proteins that pull the muscle fiber shorter can interact. Troponin T anchors the troponin
complex to the muscle fiber structure. There is little or no difference in troponin C
between skeletal and cardiac muscle, but the forms of troponin I and troponin T are
different. Measuring the amount of cardiac-specific troponin T or troponin I in the blood
can help identify individuals who have experienced damage to their heart.

Normally, troponin is present in very small to undetectable quantities in the blood. When
there is damage to heart muscle cells, troponin is released into the blood. The more
damage there is, the greater the concentration in the blood. Primarily, troponin tests are
used to help determine if an individual has suffered a heart attack. They may also be
helpful in evaluating someone for other forms of heart injury.

Many laboratories in the U.S. use high-sensitivity troponin tests since the Food and
Drug Administration (FDA) approved them in 2017. Because this version of the test is
more sensitive than previous, older versions, it becomes positive sooner and may help
detect heart injury and acute coronary syndrome earlier. The hs-troponin test may also
be positive in people with stable angina and even in people with no symptoms. When it
is elevated in these individuals, it indicates an increased risk of future heart events such
as heart attacks.

When a person has a heart attack, levels of cardiac-specific troponins I and T can
become elevated in the blood within 3 or 4 hours after injury and may remain elevated
for 10 to 14 days.

Lipid profile

Lipids are a group of fats and fat-like substances that are important constituents of cells
and sources of energy. A lipid panel measures the level of specific lipids in the blood.

Two important lipids, cholesterol and triglycerides, are transported in the blood by
lipoproteins (also called lipoprotein particles). Each type of lipoprotein contains a
combination of cholesterol, triglyceride, protein, and phospholipid molecules. The
particles measured with a lipid panel are classified by their density into high-density
lipoproteins (HDL), low-density lipoproteins (LDL), and very low-density lipoproteins
(VLDL).

A lipid panel typically includes:


 Total cholesterol—measures all the cholesterol in all the lipoprotein particles
 High-density lipoprotein cholesterol (HDL-C)—measures the cholesterol in HDL
particles; often called "good cholesterol" because HDL-C takes up excess cholesterol
and carries it to the liver for removal.
 Low-density lipoprotein cholesterol (LDL-C)—calculates or measures the cholesterol in
LDL particles; often called "bad cholesterol" because it deposits excess cholesterol in
walls of blood vessels, which can contribute to atherosclerosis. Usually, the amount of
LDL-C is calculated using the results of total cholesterol, HDL-C, and triglycerides.
 Triglycerides—measures all the triglycerides in all the lipoprotein particles; most is in the
very low-density lipoproteins (VLDL).

Some other information may be reported as part of the lipid panel. These parameters
are calculated from the results of the tests listed above.

 Very low-density lipoprotein cholesterol (VLDL-C)—calculated from triglycerides/5; this


formula is based on the typical composition of VLDL particles.
 Non-HDL-C—calculated from total cholesterol minus HDL-C
 Cholesterol/HDL ratio—calculated ratio of total cholesterol to HDL-C

An extended profile (or advanced lipid testing) may also include low-density lipoprotein
particle number or concentration (LDL-P). This test measures the number of LDL
particles, rather than measuring the amount of LDL-cholesterol. It is thought that this
value may more accurately reflect heart disease risk in certain people. (For more, see
the article on LDL Particle Testing).

Monitoring and maintaining healthy levels of these lipids is important in staying healthy.
While the body produces the cholesterol needed to function properly, the source for
some cholesterol is the diet. Eating too much of foods that are high in saturated fats and
trans unsaturated fats (trans fats) or having an inherited predisposition can result in a
high level of cholesterol in the blood. The extra cholesterol may be deposited
in plaques on the walls of blood vessels. Plaques can narrow or eventually block the
opening of blood vessels, leading to hardening of the arteries (atherosclerosis) and
increasing the risk of numerous health problems, including heart disease and stroke.

A high level of triglycerides in the blood is also associated with an increased risk of
developing cardiovascular disease (CVD), although the reason for this is not well
understood.

Glycosylated Hemoglobin or Hemoglobin A1C (HbA1C)

Reflects average blood sugar levels over the preceding 90-day period. Elevated levels
are associated with prediabetes and diabetes. Individuals with diabetes have an
increased risk of a cardiac event. A diabetic person's risk for heart attack is the same as
a non-diabetic person, who has experienced one heart attack, having a second heart
attack. Aggressive global preventive risk reduction efforts, such as lower LDL targets,
diet, exercise and blood pressure control, are recommended.
Fbs

A test that measures blood sugar levels. Elevated levels are associated with diabetes and
insulin resistance, in which the body cannot properly handle sugar (e.g. obesity).
A blood glucose test measures the glucose levels in your blood. Glucose is a type of sugar. It is your
body's main source of energy. A hormone called insulin helps move glucose from your bloodstream
into your cells. Too much or too little glucose in the blood can be a sign of a serious medical
condition. High blood glucose levels (hyperglycemia) may be a sign of diabetes, a disorder that can
cause heart disease, blindness, kidney failure and other complications. Low blood glucose levels
(hypoglycemia) can also lead to major health problems, including brain damage, if not treated.
Medline,

X ray
The heart and the lung make up an inseparable anatomic and functional unit. The changes in one affect
the other and vice versa. In acute myocardial infarction a heart failure syndrome develops. This syndrome
is characterized by passive pulmonary congestion, which leads to hypoxemia. This hypoxemia indicate
the functional disturbance of the lung, and the hemodinamic evolution of the disease. Arterial gases
determination is the best way to assess the sickness progression. A certain paralelism exists among the
central venous saturation, cardiac insufficiency and the degree of pulmonary disfunction. Such a
procedure is not very appreciable and does not substitute the direct analysis of the arterial PO2. The
pulmonary complications in the myocardial infarction shock are directly responsable of death in 50% of
the patients. To heart failure and shock, hipperfusion and hypoxia are added. Many vessels close due to
the decrease in the pulmonary flow. This brings about the release of substances that are toxic to the
vessel causing an inflammatory vascular reaction. The decrease in the flow harms the lung cell and for
this reason atelectasia or alveolar colapse occur; besides inducing the formation of shunts. Under these
conditions the lung compliance decreases.

Drug Study

ISMN

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ISDN

https://www.scribd.com/doc/17100281/Isordil

enox

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https://www.scribd.com/document/45972868/Drug-Study-2

1. Consider dosage adjustment for clients with low weight (<45kg)


2. Give only by deep SC while lying down
3. Do not give IM
4. Continue treatment until risk of DVT decreases
5. Do not mix with other injections/infusions
6. Discard any unused solution
7. Assess for Heparin or pork product hypersensitivity
8. Document baseline hematologic parameters, liver function, and coagulation
studies
9. Monitor VS and assess for signs of bleeding
10. Client may self-inject if educated and if follow-up on out-patient basis is
needed
11. Alternate administration between the left and right anterolateral and
posterolateral abdominal wall
12. Do not rub injection site
13. May experience mild discomfort, irritation, hematoma at injection site
14. Report unusual bleeding, or weakness
15. Practice reliable contraception
16. Avoid OTC agents containing aspirin
17. Use an electronic razor to shave

Atorvas

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