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Acetaminophen is a central analgesic that appears to inhibit prostaglandin synthesis in the CNS. It is indicated for relief of mild to moderate pain and fever. Major adverse effects include hepatic failure and hepatotoxicity from overdose. Nursing responsibilities include assessing the patient's medical history and liver function, instructing them on proper administration and monitoring for side effects, and educating them on drug interactions and signs of toxicity.

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Emilie Caja
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3K views

Drug Study Format

Acetaminophen is a central analgesic that appears to inhibit prostaglandin synthesis in the CNS. It is indicated for relief of mild to moderate pain and fever. Major adverse effects include hepatic failure and hepatotoxicity from overdose. Nursing responsibilities include assessing the patient's medical history and liver function, instructing them on proper administration and monitoring for side effects, and educating them on drug interactions and signs of toxicity.

Uploaded by

Emilie Caja
Copyright
© © All Rights Reserved
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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MECHANISM OF INDICATION / NURSING

DRUG NAME ADVERSE EFFECT


ACTION CONTRAINDICATION RESPONSIBILITIES

GENERIC: INDICATIONs: GI: BEFORE:

ACETAMNOPHEN Appears to inhibit Relief of mild to HEPATIC FAILURE, Dx:


prostaglandin moderate pain, fever. IV: HEPATOTOXICITY(OVERDOSE).
Assess the patient’s
synthesis in the CNS (Additional) Management
medical history and
BRAND: and, to a lesser of moderate to severe
tests to ensure
extent, block pain pain when combined with GU:
TYLENOL compatibility of drug
impulses through opioid analgesia.
,VALORIN, Renal failure (high with the patient’s
peripheral action.
PANADOL, NEOPAP doses/chronic use). current condition.
Acts centrally on
hypothalamic heat- CONTRAINDICATION:
regulating center,
CLASS: producing peripheral Severe hepatic HEMAT: Check doctor’s order
vasodilation (heat impairment or severe or prescription before
ANTIPYRETCS, active liver disease Neutropenia, pancytopenia, administration.
loss, skin erythema,
NONOPIOID leukopenia.
and diaphoresis).
ANALGESICS
Therapeutic Effect:
Results in DRUG TO DRUG Instruct patient on
antipyresis. INTERACTION: DERM: Rash, urticaria. how to take medicine.
PHARMACOLOGIC: Produces analgesic
DRUG: Alcohol (chronic
effect
CENTRAL use), hepatotoxic
(F.A. Davis. n.d.) Tx:
ANALGESIC. medications (e.g.,
phenytoin), hepatic Instruct patient to eat
enzyme inducers (e.g., before taking
ROUTE: phenytoin, rifampin) may medication
increase risk of
ORAL
hepatotoxicity with
prolonged high dose or - Instruct patient
single toxic dose. May to report if he
increase risk of bleeding or she has any
liver disease.
with warfarin with
Monitored patient’s
chronic, high-dose use.
vital signs.
HERBAL: St. John’s wort
may decrease blood
levels.
EDx:
DRUG TO FOOD
INTERACTION: Explained purpose of
medication.
None .
Advised patient to
take medication as
ordered.

Avoid alcohol use

Teach patient to
recognize signs of
chronic over dose.

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