Vince John B.

Sevilla Drugstudy

Drug Classificati Dosage Mechanism of Action Indications Contraindication Side Effects Nursing Responsibilities
on
cardiovascul  Tablet 2.5mg, These medications block Chest pain (angina) occurs  Pre-existing headache and edema  Monitor BP for
Amlodipine( ar agent; 5mg, 10mg the transport of calcium because of insufficient acute or (swelling) of the therapeutic
calcium  into the smooth muscle oxygen delivered to the heart chronic liver lower extremities. effectiveness. BP
Norvasc) channel  Patient Dosage cells lining the coronary muscles. Insufficient oxygen dysfunction Less common side reduction is greatest
blocker;  5 mg OD arteries and other arteries may be a result of coronary or family effects include after peak levels of
antihyperten of the body. Since calcium artery blockage or spasm, or history of dizziness, flushing, amlodipine are
sive agent is important in muscle because of physical exertion severe liver fatigue, nausea, and achieved 6–9 h
contraction, blocking which increases heart inflammatio palpitations following oral
calcium transport relaxes oxygen demand in a patient n (hepatitis), doses.
artery muscles and dilates with coronary artery particularly  Monitor for S&S of
coronary arteries and narrowing. Amlodipine is medicine dose-related
other arteries of the body. used for the treatment and related. peripheral or facial
prevention of angina  Known edema that may not
resulting from coronary hypersensitiv be accompanied by
spasm. Amlodipine is also ity to weight gain; rarely,
used in the treatment of high valproate or severe edema may
blood pressure any of the cause
ingredients discontinuation of
used in the drug.
preparation.  Monitor BP with
 Urea cycle postural changes.
disorders. Report postural
 Hepatic hypotension.
porphyria. Monitor more
 Hepatotoxici frequently when
ty. additional
antihypertensives or
diuretics are added.
 Monitor heart rate;
dose-related
palpitations (more
common in women)
may occur.