Molecular Basis Off Inheritance
Molecular Basis Off Inheritance
BIOLOGY
INSTRUCTION
1. The test paper contains 25 multiple choice questions Answer all the questions.
2. Each question carries four marks for correct answers and one negative mark for wrong
answer.
3. Multiple markings for the same question will be treated as a wrong answer and will
carry one negative mark.
4. For each question there are four options of which one option is correct.
5. Rough work can he done on the question paper itself.
6. Calculator / Log table is not allowed.
1. Amino acid Leucine is coded by 6 triplet codons- UUa, UUG, CUU, CUA and CUG.
Which of the following is most relevant for the statement given
(A ) Codes are non overlapping
(B) Degeneracy of code
(C) Codes are commaless
(D) Three adjacent nitrogen bases specify one amino
3. How many triplet codons are possible after full probability base substitutions in one triplet
codon.
(A) 3
(B) 6
(C) 9
(D) 27
4. How many amino acids will be coded by the sense strand of a DNA piece, whose transcript
is given below.
AUG UUU UUC UUC AUG UGG UUU UAG
(A) One
(B) Zero
(C) Six
(D) Seven
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5. Triplet nature of genetic code was proposed by
(A) Nirenberg
(B) Hoagland
(C) F.H.C. Crick
(D) Khorana
6. Considering that we have four nucleotides A, G, C and T, the number of base substitutions
that can occur in the amino acid codons are
(A) 549
(B) 564
(C) 261
(D) 256
10. During translation (protein synthesis), the enzyme that catalyses peptide bonding is
located in the
(A) Central part of the tRNA
(B) Larger subunit of the ribosome
(C) Smaller subunit of the ribosome
(D) 5’ end of the mRNA
11.Which of the following complex is formed at first during the initiation of translation in
Rhizobium?
(A) 50S subunit - mRNA complex
(B) 60S subunit - mRNA complex
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(C) 30S subunit - mRNA complex
(D) 40S subunit - mRNA complex
12. What location one can expect for “ methyl guanosine triphosphate”
(A) Structural gene of template strand
(B) 5’ end of hnRNA
(C) Overlapping genes of x 174 viruses
(D) Jumping genes of maize
14. During protein synthesis, amino acid gets attached to tRNA with the help of
(A) mRNA
(B) Aminoacyl synthetase
(C) ribosome
(D) rRNA
17. The translation step in the process of protein synthesis, in which the conversion of the
language of nucleic acid into that of proteins, is made by a charged form of
(A) mRNA
(B) tRNA
(C) rRNA
(D) Template DNA
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18. Which site of tRNA molecule forms hydrogen bonds with mRNA molecule?
(A) Codon
(B) Anticodon
(C) 5’ end of the t-RNA molecule
(4) 3’ end of the t-RNA molecule
19. To code the 50 amino acids in a polypeptide chain, what will be the minimum number of
bp in its cistron?
(A) 50
(B) 153
(C) 306
(D) 300
20. A single anticodon can recognize more than one codon of mRNA. This phenomenon is
terminated as
(A) Richmond and Lang effect
(B) Gene flow hypothesis
(C) Wobble hypothesis
(D) Transposability
23. Which of the following is pre - dominant site for control of gene expression in
prokaryotes
(A) Processing level
(B) transport of mRNA from nucleus to the cytoplasm
(C) Transcriptional initiation
(D) All of these
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24. The substrate for the enzyme 𝛽-Galactosidase is
(A) Glucose
(B) Galactose
(C) Lactose
(D) All of these