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Differences Between Dynamic and Static Pass Box

There are two main types of pass boxes used in pharmaceutical manufacturing: static and dynamic. Static pass boxes transfer materials between two equally clean environments with minimal personnel movement. Dynamic pass boxes transfer materials from uncontrolled to controlled environments, and have interlocked doors and filtration systems to prevent contamination. Key differences are that dynamic pass boxes have intake and exhaust filters, pressure gauges, blowers, and higher wattage UV lights compared to static pass boxes, which are designed simply as airlocks between clean environments.

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329 views

Differences Between Dynamic and Static Pass Box

There are two main types of pass boxes used in pharmaceutical manufacturing: static and dynamic. Static pass boxes transfer materials between two equally clean environments with minimal personnel movement. Dynamic pass boxes transfer materials from uncontrolled to controlled environments, and have interlocked doors and filtration systems to prevent contamination. Key differences are that dynamic pass boxes have intake and exhaust filters, pressure gauges, blowers, and higher wattage UV lights compared to static pass boxes, which are designed simply as airlocks between clean environments.

Uploaded by

sachin
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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DIFFERENCES BETWEEN SYNAMIC AND STATIC PASS BOX

Pass boxes have an important role in sterile area to transfer the material between two different cleanliness
levels aseptically.

In pharmaceutical manufacturing industries, pass boxes are normally used to transfer a particular material
between two areas generally of different cleanliness levels. The boxes can be said to transfer the materials
from a high level of cleanliness to a lower of cleanliness or vice-versa. The pass boxes while transferring
the material help to prevent air from flowing from one area to another. Pass boxes are made of stainless
steel which is powder coated.

There are two types of pass boxes used in pharmaceutical industries and these are:

1. Dynamic pass boxes


2. Static pass boxes

The pass boxes have similar features such as having a mechanical interlocking for the doors, UV lights,
fluorescent lamps and are both made of the same material which is stainless steel. However, with all the
similar features, there are several differences between the two types of pass boxes as they are described
below:

1. The static pass boxes which are known to transfer materials between two clean environments which
are equally clean and are designed to work with minimal personnel movement while dynamic pass
boxes are used to pass through materials from an uncontrolled environment to a controlled
environment. A static pass boxes should never be used to transfer material between a clean room
and non-clean room.
2. A dynamic pass box is a cubicle box which has got interlocked doors located on both sides. This
protects the controlled environment from being polluted while the transfer of a material is taking
place inside. A static pass box, on the other hand, has got an electromagnetic interlocking
arrangement which is located between two doors. The arrangement is fitted with an LED indicator
which helps to show whether any door is open.
3. A dynamic pass box has got a system known as an interlock guard which helps to control both the
outlet and the inlet so that there is no time that the two are opened. Due to this, dirt and other
loose particles are removed from the materials being transferred to the manufacturing area and vice
versa but a static pass box doesn’t have such a feature since it only transfers material between two
equally clean environments.
4. A dynamic pass box is fitted with a suction filter of around 0.3 microns that is a stainless steel
product and a supply filter of about 10 microns that is made of aluminum. A static pass box doesn’t
have the filters. The dynamic pass box also has a pressure gauge ranging from 0 to 25 mmwc. It is
also fitted with a motor blower of 1/5 hp for blowing out dust particles. The static pass box is
designed as an air lock device to prevent air from entering or clean air form disappearing from the
clean room.
5. For a dynamic pass box, the ultraviolet light’s specifications are 18 watts while that of a static pass
box is 8 watts. The ultraviolet light with hour meter is controlled by the interlocking arrangement
and it goes off whenever any of the doors open.

The fluorescent lamp in a static pass box is about 40 watts while that of a dynamic pass box is about 20
watts. The lamp is controlled by the interlocking arrangement and when the doors are in a closed
position, the lamp is on.

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