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Laboratory Biosecurity Concepts

The document discusses laboratory biosecurity concepts. It defines laboratory biosafety as measures to prevent accidental exposure to pathogens through good practices and containment. Laboratory biosecurity refers to security measures to prevent intentional loss, theft or release of pathogens. An effective biosecurity program is tailored to each facility based on its work, risks, and input from staff.

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Christopher Philip
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93 views

Laboratory Biosecurity Concepts

The document discusses laboratory biosecurity concepts. It defines laboratory biosafety as measures to prevent accidental exposure to pathogens through good practices and containment. Laboratory biosecurity refers to security measures to prevent intentional loss, theft or release of pathogens. An effective biosecurity program is tailored to each facility based on its work, risks, and input from staff.

Uploaded by

Christopher Philip
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Laboratory biosecurity concepts

In the past, the traditional biosafety guidance for


laboratories was the focus of the laboratory
biosafety manual. The manual stresses the use of
good microbiological
work practices, appropriate containment
equipment, proper facility design, operation and
maintenance, and administrative considerations to
minimize the risk of worker
injury or illness. The risk to the environment and
surrounding community-at-large is minimized when
such advice is being followed. Global incidents in
the recent past have highlighted the need to
protect laboratories and the materials they contain
from being intentionally compromised in ways that
may harm people, livestock, agriculture or the
environment. It is
important to understand the distinction between
“laboratory biosafety” and “laboratory
biosecurity”.
“Laboratory biosafety” is the term used to
describe the containment principles, technologies
and practices that are implemented to prevent
unintentional exposure to pathogens and toxins, or
their accidental release.
“Laboratory biosecurity” refers to pathogens and
toxins, or their accidental release.
“Laboratory biosecurity” refers to institutional and
personal security measures designed to prevent
the loss, theft, misuse,
diversion or intentional release of pathogens and
toxins.
A specific laboratory biosecurity programme
must be prepared and implemented
for each facility according to the requirements of
the facility, the type of laboratory
work conducted, and the local conditions.
Consequently, laboratory biosecurity
activities should be representative of the
institution’s various needs and should include
input from scientific directors, principal
investigators, biosafety officers, laboratory
scientific staff, maintenance staff, administrators,
information technology staff, and
law enforcement agencies and security staff if
appropriate.

Biological safety cabinets


Class I biological safety cabinet
Table 8. Selection of a biological safety cabinet (BSC), by type of
protection needed

TYPE OF PROTECTION BSC SELECTION


Personnel protection, Class I, Class II, Class III
microorganisms in Risk Groups 1–3

Personnel protection, Class III


microorganisms
in Risk Group 4, glove-box
laboratory
Personnel protection, Class I, Class II
microorganisms in Risk Group 4, suit
laboratory
Product protection Class II, Class III only if laminar flow
included
Volatile radionuclide/chemical Class IIB1, Class IIA2 vented to the
protection, minute amounts outside
Volatile radionuclide/chemical Class I, Class IIB2, Class III
protection

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