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Vitamins Assignment 6

The document discusses the role of vitamins and minerals in atherosclerosis. It covers how vitamin D, vitamin K2, and vitamin E impact atherosclerosis progression and mechanisms. It also mentions how supplemental vitamins and minerals can impact atherosclerosis.

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Maryam Shahzadi
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23 views3 pages

Vitamins Assignment 6

The document discusses the role of vitamins and minerals in atherosclerosis. It covers how vitamin D, vitamin K2, and vitamin E impact atherosclerosis progression and mechanisms. It also mentions how supplemental vitamins and minerals can impact atherosclerosis.

Uploaded by

Maryam Shahzadi
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Role of vitamins and minerals

SUBMITTED TO Maam Sundas Arshad


SUBMITTED BY Maryam Shahzadi
SAP ID 70076221
COURSE ADHNVNM
DEPARTMENT BDNS
SEMESTER 02
ASSIGNMENT NO. 06

01
Role of vitamins and minerals

Assignment No. 06
Role of vitamins and minerals supplementations in
atherosclerosis.
Atherosclerosis, the principal cause of cardiovascular diseases (CVDs), is a process that involves
a complex interplay among different factors and cell types, including cells of the immune
system (T cells, B cells, natural killer cells, monocytes/macrophages, dendritic cells) and cells of
the vessel wall (endothelial cells [ECs], vascular smooth muscle cells [VSMCs]). The atherogenic
process evolves in different stages, starting from inflammatory endothelial
activation/dysfunction and resulting in plaque vulnerability and rupture.

Vitamin D Metabolism and Mechanism of Action

Vitamin K2 Reduces the Progression of Arterial Thickening


The impact of vitamin K2 on atherosclerosis is due to its role in activating a group of proteins
whose job it is to keep calcium in the bones and out of the arteries.

In bones, vitamin K2 activates a specific protein called osteocalcin. When osteocalcin is


activated by vitamin K2, it binds calcium tightly to bone minerals to create strong bones. In
arteries, vitamin K2 activates a protein called matrix Gla protein. When matrix Gl a protein is
activated by vitamin K2, it prevents calcium from being deposited in arteries.

02
Role of vitamins and minerals

When vitamin K2 is not present in sufficient enough quantities to activate these two proteins,
the result is an increased risk for developing osteoporosis and atherosclerosis because of
calcium loss from the bones.

Supplemental Vitamins and Minerals

The role of vitamin E in atherosclerosis

Atherosclerotic Progression

03

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