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Praktikum Faal - PhysioEx Fisiologi Otot PDF

This document contains the results of a student's lab report on skeletal muscle physiology and fatigue in isolated skeletal muscle. The student scored 100% on pre-lab and post-lab quizzes. According to the experiment results, when brief rest periods were imposed by turning the stimulator off, the length of time the muscle could sustain maximal tension increased proportionately to the length of the rest period.

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Feri Almana
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75 views5 pages

Praktikum Faal - PhysioEx Fisiologi Otot PDF

This document contains the results of a student's lab report on skeletal muscle physiology and fatigue in isolated skeletal muscle. The student scored 100% on pre-lab and post-lab quizzes. According to the experiment results, when brief rest periods were imposed by turning the stimulator off, the length of time the muscle could sustain maximal tension increased proportionately to the length of the rest period.

Uploaded by

Feri Almana
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Name: Dewi Rarasati K.

021911133089

Exercise 2: Skeletal Muscle Physiology: Activity 5: Fatigue in Isolated Skeletal Muscle Lab Report

Pre-lab Quiz Results


You scored 100% by answering 4 out of 4 questions correctly.

1. When skeletal muscle twitches fuse so that the peaks and valleys of each twitch become indistinguishable from each
other, the muscle is in a state known as
You correctly answered: d. complete (fused) tetanus.

2. When the stimulus frequency reaches a value beyond which no further increase of skeletal muscle force can occur, the
muscle has reached its
You correctly answered: c. maximal tetanic tension.

3. A decline in a muscle's ability to maintain a constant level of force, or tension, after prolonged, repetitive stimulation is
called
You correctly answered: c. fatigue.

4. Which of the following is not thought to be a contributing factor to the development of fatigue?
You correctly answered: a. buildup of Ca2+ in the muscle fibers

05/11/20 page 1
Experiment Results
Predict Question:
Predict Question: If the stimulator is briefly turned off for defined periods of time, what will happen to the length of time that
the muscle is able to sustain maximal developed tension when the stimulator is turned on again?
Your answer : b. The length of the rest period will proportionately increase the length of time for sustained muscle tension.

Stop & Think Questions:


Why does the stimulated muscle force begin to decrease over time despite the maintained stimuli? (Note that a decrease in
maximal force indicates muscle fatigue is developing.)
You correctly answered: d. More than one of these answers could be correct.

Why did the length of the intervening rest period affect the length of time the skeletal muscle can maintain maximum tension
once the stimulator is turned on again?
You correctly answered: c. Intracellular concentrations of ADP and Pi declined during the rest period.

Experiment Data:

Voltage Stimuli/sec Rest Period (sec) Active Force (g) Sustained Maximal Force
(sec)
8.5 120 0 5.86 10
8.5 120 0 5.86 10
8.5 120 12 5.86 1.80
8.5 120 22 5.86 5.80

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Post-lab Quiz Results
You scored 100% by answering 5 out of 5 questions correctly.

1. During cross bridge cycling in skeletal muscle, force is created by the


You correctly answered: c. power stroke of the myosin heads.

2. The term tetanus refers to


You correctly answered: b. sustained muscle tension due to repetitive stimuli.

3. A decline in a muscle's ability to maintain a constant level of force, or tension, after prolonged, repetitive stimulation is
called
You correctly answered: c. fatigue.

4. During fatigue
You correctly answered: c. the number of active cross bridges begins to decline although the rate of stimulus delivery
(frequency) remains constant.

5. If an intervening rest period is imposed on active skeletal muscle


You correctly answered: c. the development of fatigue will be delayed.

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Review Sheet Results
1. When a skeletal muscle fatigues, what happens to the contractile force over time?
Your answer:
When a skeletal muscle fatigues, contractile force decrease because force isn't generated any more after reaching maximal
tetanic tension by previous contractile activity.

2. What are some proposed causes of skeletal muscle fatigue?


Your answer:
the high concentration of lactic acid, ADP, and inorganic phosphate (Pi)

3. Turning the stimulator off allows a small measure of muscle recovery. Thus, the muscle will produce more force for a
longer time period if the stimulator is briefly turned off than if the stimuli were allowed to continue without interruption.
Explain why this might occur. How well did the results compare with your prediction?
Your answer:
our prediction is suitable with the result, by turning the stimulator off, the period of rest is created, this allowing the
concentrations of lactic acid, ADP, and Pi to decrease, therefore the muscle is able to maintain maximum tension increases.

4. List a few ways that humans could delay the onset of fatigue when they are vigorously using their skeletal muscles.
Your answer:
a. Periodically, take a few breaks during exercise
b. Exercise frequently

Dewi Rarasati Kresnaputri 021911133089


Al Khansa Shafa Arsy 021911133095
Winni Langgeng Kuntari 021911133100

05/11/20 page 5

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