Scribd
Upload
97 views

Accreditation Board For Engineering and Technology (ABET) Criteria For Biomedical Engineering

Intro to biomaterials

Uploaded by

HcYeb Kahn
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
97 views

Accreditation Board For Engineering and Technology (ABET) Criteria For Biomedical Engineering

Intro to biomaterials

Uploaded by

HcYeb Kahn
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 2

Biomaterials

Biomaterial is a science/engineering discipline for studying and developing matters, surfaces, and structures
(excluding pharmaceuticals) that interact and are compatible with biological systems. Biomaterials science,
which has a history of about 50 years, encompasses elements of medicine, biology, chemistry, physics, and tissue
engineering.

Accreditation Board for Engineering and Technology (ABET) Criteria for Biomedical Engineering

The structure of the curriculum must provide both breadth and depth across the range of engineering
topics implied by the title of the program. The program must prepare graduates to have: an
understanding of biology and physiology, and the capability to apply advanced mathematics
(including differential equations and statistics), science, and engineering to solve the problems at the
interface of engineering and biology; the curriculum must prepare graduates with the ability to make
measurements on and interpret data from living systems, addressing the problems associated with the
interaction between living and non-living materials and systems.

Classification based on biocompatibility

Biocompatibility is concerned with the


acceptance of an artificial implant by the
surrounding tissues and by the body as a whole.

1. Bioinert
The term bioinert refers to any material that
once placed in the human body has minimal
interaction with its surrounding tissue, examples
of these are stainless steel, titanium, alumina,
partially stabilized zirconia, and ultra high
molecular weight polyethylene. Generally a
fibrous capsule might form around bioinert Figure 1. Classification of biomaterials according to their
bioactivity (a) bioinert alumina dental implant, (b) bioactive
implants hence its biofunctionality relies on
hydroxyapatite [Ca10(PO4)6(OH)2] coating on a metallic dental
tissue integration through the implant (Figure implant, (c) surface active bioglass and (d) bioresorbable tricalcium
1b). phosphate ([Ca3(PO4)2] implant. Source: <www.azom.com.com/
article.aspx?ArticleID=2630>.
2. Bioactive
Bioactive refers to a material, which upon being placed within the human body interacts with the surrounding
bone and in some cases, even soft tissue. This occurs through a time – dependent kinetic modification of the
surface, triggered by their implantation within the living bone. An ion – exchange reaction between the bioactive
implant and surrounding body fluids – results in the formation of a biologically active carbonate apatite (CHAp)
layer on the implant that is chemically and crystallographically equivalent to the mineral phase in bone. Prime
examples of these materials are synthetic hydroxyapatite [Ca10(PO4)6(OH)2], glass ceramic A-W and Bioglass®
(Figure 1b and c).

3. Bioresorbable
Bioresorbable refers to a material that upon placement within the human body starts to dissolve (resorbed) and
slowly replaced by advancing tissue (such as bone). Common examples of bioresorbable materials are tricalcium
phosphate [Ca3(PO4)2] and polylactic–polyglycolic acid copolymers. Calcium oxide, calcium carbonate and
gypsum are other common materials that have been utilized during the last three decades (Figure 1d).
Classification based on material source
1. Natural
Autograft – tissue transplanted from another part of the body pf the same individual
Allograft – from a donor of the same species
Xenograft – from a donor of a different species
Isograft – from am identical twin
2. Synthetic – Metals, ceramics, polymers

Uses of Biomaterials
Uses of Biomaterials Example
Replacement of diseased/damaged part Artificial hip joint, kidney dialysis machine
Assist in healing Sutures, bone plates, screws
Improve function Cardiac pacemaker, intra-ocular lens
Correct functional abnormalities Cardiac pacemaker
Correct cosmetic problem Mastectomy augmentation, chin augmentation
Aid to diagnosis Probes and catheters
Aid to treatment Catheters, drains

Materials for Use in the Body


Materials Advantages Disadvantages Examples
Polymers Resilient, easy to Not strong, deforms Blood vessels, sutures, ear, nose,
nylon, silicon rubber, polyester, fabricate, with time, may degrade soft tissues
PTFE, etc
Metals Strong tough ductile May corrode, dense, Joint replacement, bone plates
Ti and its alloys, Co-Cr alloys, difficult to make and screws, dental root implant,
stainless steels pacer, suture
Ceramics Very biocompatible, Difficult to make, Dental coating, orthopedic
aluminum oxide, calcium inert, strong in brittle, not resilient implants, femoral head of hip
phosphates including compression
hydroxyapatite carbon
Composites Compression strong Difficult to make Joint implants, heart valves
carbon-carbon, wire, fiber
reinforced bone cement

Tissue Engineering
Tissue engineering is concerned with the use of a combination of cells, engineering and materials methods, and
suitable biochemical and physio-chemical factors to improve or replace biological functions. (Tissue
Engineering has the tendency of growing out of the biomaterials field to become a separate field.)

You might also like