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Medication: Expected Pharmacological Action Therapeutic Use

Methylene blue is used to treat acquired methmoglobinemia by promoting the non-enzymatic conversion of metHb to hemoglobin. It works by being converted to leukomethylene blue, which then reduces the ferric iron of metHb to ferrous iron in normal hemoglobin. Complications include serotonin syndrome, hemolytic anemia, anaphylaxis, and others. It is administered intravenously while monitoring for side effects and methomoglobin levels. Interactions with SSRIs and SNRIs can increase the risk of serotonin syndrome.

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Aiyanna Rankins
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348 views1 page

Medication: Expected Pharmacological Action Therapeutic Use

Methylene blue is used to treat acquired methmoglobinemia by promoting the non-enzymatic conversion of metHb to hemoglobin. It works by being converted to leukomethylene blue, which then reduces the ferric iron of metHb to ferrous iron in normal hemoglobin. Complications include serotonin syndrome, hemolytic anemia, anaphylaxis, and others. It is administered intravenously while monitoring for side effects and methomoglobin levels. Interactions with SSRIs and SNRIs can increase the risk of serotonin syndrome.

Uploaded by

Aiyanna Rankins
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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ACTIVE LEARNING TEMPLATE: Medication

STUDENT NAME______________________________________
Methylene Blue (ProvayBlue)
MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________

CATEGORY CLASS__oxidation reduction agent


_____________________________________________________________________

PURPOSE OF MEDICATION

Expected Pharmacological Action Therapeutic Use


promotes a non-enyzmatic redox conversion Treatment of acquired methmoglobinemia;
of metHb to hemoglobin, methylene blue is UTI analgesic, improves hypotension,
converted to (LMB) which then reduces the hypoxia, and cardiac function in septic shock
ferric iron of metHb to ferrous in normal Hgb

Complications Medication Administration


Serotonin syndorme, hemolytic anemia, anaphylaxis, IV
burning/pain at IV site, limb discomfort, dyspnea, N/V/D,
palpitations, blurred vision

Contraindications/Precautions
Hypersensitivity; patients with G6PD
Nursing Interventions
Monitor VS, ECG, CBC, and
methomoglobin levels during
therapy
Assess for s/s of serotonin
syndrome and anaphylaxis
Interactions
SSRI, SNRIs, and monamine oxidase inhibtors- increased
risk of seratonin syndrome

Client Education
May cause blue discoloration of
skin and body fluids
Evaluation of Medication Effectiveness Wear protective clothing to
improvement of methoglobinemia avoid photosensitivity reactions
Avoid driving d/t dizziness
Report s/s serotonin syndrome
promptly

ACTIVE LEARNING TEMPLATES

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