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PN Compounding: Checklist

This document provides a checklist for pharmacy staff to safely prepare parenteral nutrition (PN) formulations. It outlines guidelines for setup and use of an automated compounding device, criteria for manual compounding of PN, and standards for commercial PN products and order review. The purpose is to promote optimal and safe PN practices by verifying ingredients, concentrations, equipment, and procedures to maximize benefits and minimize risks of this complex therapy.

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Ann Dahng
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54 views

PN Compounding: Checklist

This document provides a checklist for pharmacy staff to safely prepare parenteral nutrition (PN) formulations. It outlines guidelines for setup and use of an automated compounding device, criteria for manual compounding of PN, and standards for commercial PN products and order review. The purpose is to promote optimal and safe PN practices by verifying ingredients, concentrations, equipment, and procedures to maximize benefits and minimize risks of this complex therapy.

Uploaded by

Ann Dahng
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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PN Compounding Checklist

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The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) champions the best evidence-based practices that
support parenteral nutrition (PN) therapy in varying age populations and disease states. The appropriate use of this complex
therapy aims to maximize clinical benefit while minimizing the potential risks for adverse events.

The purpose of this checklist is to promote safe practices by pharmacy staff to prepare optimal PN formulations.

Automated Compounding Device (ACD) Setup T here is a chemical reaction between


Use vendor-validated setup for ACD PN components that cannot be
mitigated by sequencing the addition
Initial - ACD setup performed using 2 staff
of ingredients
members:
There is a shortage of a specific PN
Use independent double-check process
components and manual compounding
Use printed check is part of a conservation measure
Verbally affirm all additives and base Verify and inspect manual additive vials
solutions including and syringes with the additive prior to
• name adding to PN (Do not use proxy methods
• concentration of verification such as syringe pull-back
• container size method)
Use barcode technology to verify products Use check list or sign-off sheet for manual
during setup and replacement of additives
ingredients
Trace tubing from the source container to Standardized, Commercial - Parenteral Nutrition
port where attached to ACD during initial Products
setup and with each change in the source Open seal/remove bar between the
container chambers, mix components, and add
Pharmacist verifies all empty containers other components prior to dispensing from
when multiple containers of a single pharmacy.
additive are used
Use ACD to deliver all ingredients Review and verify PN order
After initial order entry
Manual compounding Prior to injecting manual additives
Use manual compounding when After compounding
The volume of PN component to
be mixed is less than the ACD can Prior to dispensing PN
accurately deliver Review and compare PN order, label on
There is an interaction between a PN PN product and compounding label prior to
component and a component of the dispensing
ACD (e.g., insulin and tubing) Visually inspect PN

For full recommendations, rationale, and references,


go to Ayers P, Adams S, Boullata J, Gervasio J,
Holcombe B, Kraft M, et al. A.S.P.E.N. Parenteral
Nutrition Safety Consensus Recommendations.
JPEN J Parenter Enteral Nutr. 2014;38:296-333.
www.nutritioncare.org/pnsafety

www.nutritioncare.org

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