General Microbiology - Introduction - 1
General Microbiology - Introduction - 1
Microbiology is the study of organisms and agents that are generally too small to be seen clearly by
the unaided eye. These organisms include viruses, bacteria, algae, fungi, and protozoa.
Microorganisms included :
Bacteria - simple, single cell
Fungi - single & multi cell forms - yeast, filamentous molds, complex fungi
Viruses - acellular, intracellular parasites
Microbiology is linked to many other scientific disciplines including biochemistry, cell biology,
evolution, ecology.
DIVISIONS OF MICROBIOLOGY
A. Organisms studied
* Bacteriology – study of bacteria
* Mycology – study of fungi
* Phycology - study of algae
* Protozoology – study of protozoa
* Virology - study of viruses
* Parasitology – study of parasites
B. Health related
* Etiology – identification of causative agent of disease
* Epidemiology – study of spread of disease
* Immunology – study of immune system
* Chemotherapy – treatment of disease with chemical compounds
* Infection control – control of spread of infectious disease
C. Processes and Functions
* Microbial metabolism – Physiology include growth characteristic and nutrition
* Microbial genetics – DNA / RNA role in product formation
* Microbial ecology – interaction among other or same genera / species and environment
Microbiology is the study of microorganisms, that is the organisms which are of microscopic
dimensions. These organisms are too small to be clearly perceived by the unaided human eye.
If an object has a diameter of less than 0.1 mm, the eye can not perceive (or more correctly
resolve) it at all, and very little detail can be perceived in an object with a diameter of I mm. Roughly
speaking organisms with a diameter of 1 mm or less are microorganisms and fall into the broad
domain of microbiology. Since most microorganisms are only a few thousandths of a millimeter in size
they can only be seen with the aid of microscope.
Viruses are ultramicroscopic and have an obligate parasitic relationship, but for practical
purposes these still come under the domain of microbiology.
As a direct consequence of the invisibility of microbes to the naked eye and the need for special
techniques to study them, microbiology was the last of the three major divisions in biology (the other
two are botany and zoology to develop.
At present, there is general agreement to include five major groups as microorganisms: the
subdivisions of virology, bacteriology, mycology, phycology and protozoology (the studies of
viruses, bacteria, fungi, algae and protozoa respectively).
Although microorganisms have existed for a long time, their existence was unknown until the
invention of the microscope in the 17th century. The year 1674, marks the birth of microbiology
when Antony van Leeu-wenhoek , a Dutch cloth merchant, looked at a drop of lake water through
a glass lens which he had ground.
What he observed through this simple magnifying lens was an amazing sight since that was perhaps
the first time that man ever had a glimpse of the world of the microbes (called as animalcules).
B. Normal flora
1. Beneficial metabolic functions
2. Antagonistic effect - prevents invasion pathogens, over growth of potential pathogens
3. Normal flora vs. pathogen identification
C. Environmental importance
1. Decomposers
2. Produce oxygen
3. Food chain
4. Sewage treatment
D. Industrial importance
1. Food industry
2. Brewing industry
3. Pharmaceutical industry
4. Genetic engineering